{"id":5660,"date":"2026-01-23T14:38:27","date_gmt":"2026-01-23T14:38:27","guid":{"rendered":"https:\/\/regenerated.health\/osteoarthritis-treatment\/"},"modified":"2026-06-25T14:35:57","modified_gmt":"2026-06-25T14:35:57","slug":"osteoarthritis-treatment","status":"publish","type":"post","link":"https:\/\/regenerated.com\/blog\/osteoarthritis-treatment\/","title":{"rendered":"Osteoarthritis Treatment: From Joint Preservation to Regenerative Therapies"},"content":{"rendered":"\n<div class=\"at-a-glance\">\n<h2>At a Glance<\/h2>\n<ul>\n<li>Osteoarthritis is not simple &#8220;wear and tear&#8221; but an active inflammatory process involving cartilage breakdown, bone remodeling, and synovial inflammation<\/li>\n<li>First-line treatments include weight management, targeted exercise, physical therapy, and anti-inflammatory dietary changes<\/li>\n<li>Conventional medical options range from NSAIDs and cortisone injections to partial or total joint replacement surgery<\/li>\n<li>Regenerative therapies, including PRP, stem cell injections, prolotherapy, and hyaluronic acid, aim to slow or reverse joint damage rather than simply manage symptoms<\/li>\n<li>The best outcomes typically combine multiple approaches, and early intervention preserves more joint function than waiting until cartilage is gone<\/li>\n<\/ul>\n<\/div>\n\n<h2>Osteoarthritis Is Not Just &#8220;Wear and Tear&#8221;<\/h2>\n\n<p>For decades, doctors described osteoarthritis (OA) as a degenerative condition caused by mechanical wear on joint cartilage. That framing made it sound inevitable and irreversible, like brake pads grinding down. But research over the past two decades has fundamentally changed how we understand this disease.<\/p>\n\n<p>OA is an active biological process. Yes, mechanical stress plays a role, but the real driver is chronic low-grade inflammation within the joint. Inflammatory cytokines like interleukin-1 beta (IL-1\u03b2) and tumor necrosis factor alpha (TNF-\u03b1) accelerate cartilage destruction by activating enzymes called matrix metalloproteinases (MMPs) that break down the collagen and proteoglycan matrix of cartilage [1]. The synovial membrane becomes inflamed, subchondral bone remodels, and osteophytes (bone spurs) form as the body tries to stabilize a joint that is losing structural integrity.<\/p>\n\n<p>This distinction matters because it opens the door to treatments that target the underlying biology, not just the symptoms. If OA were purely mechanical, the only real options would be pain management and eventual surgery. Because it involves inflammation, immune signaling, and tissue remodeling, there are interventions that can genuinely slow or modify the disease process.<\/p>\n\n<h2>Conventional Treatments: What Works and What Falls Short<\/h2>\n\n<h3>Physical Therapy and Targeted Exercise<\/h3>\n\n<p>Physical therapy remains one of the most effective and underutilized osteoarthritis treatments. A 2015 meta-analysis of 54 randomized controlled trials found that exercise therapy reduced knee OA pain by roughly 40% and improved physical function by about 30%, effects comparable to many medications without the side effects [2].<\/p>\n\n<p>The key is specificity. A good physical therapist will identify which muscles around the joint are weak or imbalanced, design a strengthening program to offload the damaged compartment, and teach movement patterns that reduce joint stress. For knee OA, quadriceps strengthening alone can dramatically reduce pain and improve function [3].<\/p>\n\n<h3>NSAIDs and Acetaminophen<\/h3>\n\n<p>Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, naproxen, and celecoxib are the most commonly prescribed medications for OA. They reduce pain and inflammation, and they work, at least in the short term. The problem is long-term use. Chronic NSAID use increases risks of gastrointestinal bleeding, kidney damage, and cardiovascular events [4]. Topical NSAIDs (like diclofenac gel) offer a safer alternative for accessible joints like the knee and hand, delivering anti-inflammatory effects locally with less systemic exposure.<\/p>\n\n<p>Acetaminophen (Tylenol) was once considered first-line for OA pain, but recent evidence shows it provides minimal benefit for osteoarthritis, only slightly better than placebo in most trials [5]. It also carries liver toxicity risk at higher doses.<\/p>\n\n<h3>Corticosteroid Injections<\/h3>\n\n<p>Cortisone shots provide rapid, potent anti-inflammatory relief inside the joint. A single injection can reduce pain for weeks to months. However, repeated corticosteroid injections may actually accelerate cartilage loss over time. A landmark 2017 randomized trial published in JAMA found that patients receiving cortisone injections every 3 months for 2 years had significantly greater cartilage volume loss compared to saline placebo injections [6].<\/p>\n\n<p>This does not mean cortisone is always harmful. For acute flares or bridging to other treatments, a well-timed injection can be valuable. But the evidence argues against using them as a long-term management strategy, which unfortunately is exactly how many patients receive them.<\/p>\n\n<h3>Joint Replacement Surgery<\/h3>\n\n<p>Total joint replacement (arthroplasty) remains the definitive treatment for end-stage OA. Modern knee and hip replacements have excellent outcomes: roughly 90-95% of patients report significant pain relief, and prosthetics now last 15-25 years in most cases [7]. For someone with bone-on-bone arthritis who has exhausted conservative measures, surgery can be transformative.<\/p>\n\n<p>But surgery is a major procedure with real risks (infection, blood clots, implant loosening, persistent pain in a subset of patients). It also has a ceiling: prosthetic joints don&#8217;t function exactly like natural ones, and revision surgery, if needed later, is more complex. The goal of most regenerative approaches is to delay or avoid that threshold.<\/p>\n\n<h2>Regenerative Therapies: Targeting the Biology of OA<\/h2>\n\n<h3>Platelet-Rich Plasma (PRP)<\/h3>\n\n<p>PRP involves drawing the patient&#8217;s blood, concentrating the platelets (which contain hundreds of growth factors), and injecting that concentrate directly into the arthritic joint. The growth factors in PRP, including platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-\u03b2), and vascular endothelial growth factor (VEGF), promote tissue repair and modulate inflammation [8].<\/p>\n\n<p>The clinical evidence for PRP in knee OA is now reasonably strong. A 2019 meta-analysis of 30 randomized controlled trials found that PRP injections significantly outperformed hyaluronic acid and corticosteroid injections for both pain relief and functional improvement at 6 and 12 months [9]. The benefits appear most robust in early to moderate OA (Kellgren-Lawrence grades 1-3); patients with severe, bone-on-bone disease tend to respond less well.<\/p>\n\n<p>Not all PRP is created equal. Leukocyte-poor PRP (LP-PRP) appears to produce better results in joints than leukocyte-rich formulations, likely because the white blood cells in leukocyte-rich PRP can trigger additional inflammation [10]. The concentration of platelets, activation method, and number of injections also influence outcomes. This variability in preparation is one reason study results have been inconsistent.<\/p>\n\n<h3>Mesenchymal Stem Cell (MSC) Therapy<\/h3>\n\n<p>Stem cell therapy for osteoarthritis typically involves harvesting mesenchymal stem cells (or more accurately, mesenchymal stromal cells) from the patient&#8217;s bone marrow or adipose tissue, processing them, and injecting them into the joint. These cells don&#8217;t simply &#8220;rebuild&#8221; cartilage on their own. Instead, they release a complex mixture of anti-inflammatory cytokines, growth factors, and extracellular vesicles that modulate the joint environment [11].<\/p>\n\n<p>Clinical trial data is growing. A 2020 systematic review of 36 clinical studies found that MSC injections generally improved pain and function in knee OA, with some studies showing evidence of cartilage regeneration on MRI [12]. However, the quality of evidence remains moderate, with significant variability in cell source, dose, processing methods, and outcome measures across studies.<\/p>\n\n<p>Cost is a significant barrier. MSC procedures typically range from $3,000-$10,000 per joint and are rarely covered by insurance. Patients should be cautious of clinics making exaggerated claims, and should look for practitioners who use evidence-based protocols and can discuss realistic expectations.<\/p>\n\n<h3>Prolotherapy<\/h3>\n\n<p>Prolotherapy involves injecting an irritant solution (most commonly hypertonic dextrose, a concentrated sugar solution) into and around the joint to stimulate a controlled inflammatory healing response. The theory is that this controlled inflammation triggers the body&#8217;s repair mechanisms, strengthening ligaments and potentially stimulating cartilage repair [13].<\/p>\n\n<p>Evidence for prolotherapy in OA is more limited than for PRP but still encouraging. A randomized controlled trial published in the Annals of Family Medicine found that dextrose prolotherapy produced clinically meaningful improvements in pain, function, and stiffness in knee OA patients that persisted at 1-year follow-up [14]. It is also considerably less expensive than PRP or stem cell treatments, making it an accessible option.<\/p>\n\n<h3>Hyaluronic Acid Injections (Viscosupplementation)<\/h3>\n\n<p>Hyaluronic acid (HA) is a naturally occurring component of synovial fluid. In OA joints, the concentration and molecular weight of HA decreases, reducing the fluid&#8217;s ability to lubricate and cushion the joint. Viscosupplementation aims to restore these properties [15].<\/p>\n\n<p>The evidence for HA injections is mixed. Some meta-analyses show modest pain reduction compared to placebo, while others find minimal benefit. A Cochrane review found that HA injections provided a small but statistically significant improvement in pain for knee OA, roughly equivalent to NSAIDs [16]. Results seem to be better with higher molecular weight products and in patients with mild to moderate OA.<\/p>\n\n<p>HA injections are FDA-approved, generally safe, and covered by some insurance plans. They may work best as part of a combined approach rather than a standalone treatment.<\/p>\n\n<h2>Lifestyle Factors: The Foundation of OA Management<\/h2>\n\n<h3>Weight Management<\/h3>\n\n<p>Excess body weight is one of the strongest modifiable risk factors for OA progression, particularly in weight-bearing joints. Every pound of body weight translates to roughly 3-6 pounds of force across the knee during walking [17]. A weight loss of just 10% of body weight has been shown to reduce knee pain by approximately 50% and significantly slow structural disease progression [18].<\/p>\n\n<p>But weight affects OA through more than just mechanical load. Adipose tissue is metabolically active, producing inflammatory adipokines (like leptin and adiponectin) that directly contribute to cartilage degradation. This partly explains why obesity also increases OA risk in non-weight-bearing joints like the hands.<\/p>\n\n<h3>Anti-Inflammatory Diet<\/h3>\n\n<p>Dietary patterns that reduce systemic inflammation can influence OA symptoms and progression. The Mediterranean diet, rich in omega-3 fatty acids, polyphenols, and fiber while low in processed foods and refined sugars, has been associated with lower OA prevalence and reduced symptom severity in observational studies [19].<\/p>\n\n<p>Specific nutrients with evidence for joint health include:<\/p>\n\n<ul>\n<li><strong>Omega-3 fatty acids:<\/strong> Reduce synovial inflammation and may slow cartilage degradation. Found in fatty fish, walnuts, and flaxseed.<\/li>\n<li><strong>Vitamin D:<\/strong> Deficiency is associated with faster OA progression. Testing and supplementation when deficient is reasonable.<\/li>\n<li><strong>Curcumin (from turmeric):<\/strong> Multiple RCTs show anti-inflammatory effects comparable to ibuprofen for OA pain, particularly in bioavailable formulations [20].<\/li>\n<li><strong>Collagen peptides:<\/strong> A 2019 meta-analysis found modest benefits for joint pain and function with daily collagen supplementation [21].<\/li>\n<\/ul>\n\n<h3>Exercise as Medicine<\/h3>\n\n<p>This deserves emphasis because so many OA patients avoid exercise out of fear that movement will worsen their joints. The opposite is true. Articular cartilage has no blood supply; it depends on the pumping action of joint loading and unloading to receive nutrients from synovial fluid. A sedentary joint is a starving joint.<\/p>\n\n<p>Research consistently shows that appropriate exercise does not accelerate cartilage loss and actually slows OA progression. A combination of strengthening, flexibility, and low-impact aerobic exercise produces the best results [22]. Swimming, cycling, walking, tai chi, and yoga all have evidence supporting their use in OA management.<\/p>\n\n<h2>Building a Treatment Strategy: The Stepwise Approach<\/h2>\n\n<p>OA treatment should be tailored to disease severity, the specific joint involved, individual risk factors, and patient goals. A reasonable stepwise approach looks like this:<\/p>\n\n<h3>Stage 1: Mild OA (Kellgren-Lawrence 1-2)<\/h3>\n\n<ul>\n<li>Weight optimization if overweight<\/li>\n<li>Structured exercise program (ideally with physical therapy guidance initially)<\/li>\n<li>Anti-inflammatory dietary changes<\/li>\n<li>Topical NSAIDs as needed<\/li>\n<li>Consider prolotherapy or PRP to slow progression<\/li>\n<\/ul>\n\n<h3>Stage 2: Moderate OA (Kellgren-Lawrence 2-3)<\/h3>\n\n<ul>\n<li>All of the above, intensified<\/li>\n<li>PRP injection series (typically 1-3 injections)<\/li>\n<li>Hyaluronic acid injections<\/li>\n<li>Oral NSAIDs for flares (short courses)<\/li>\n<li>Bracing or orthotics to offload the affected compartment<\/li>\n<li>Consider MSC therapy<\/li>\n<\/ul>\n\n<h3>Stage 3: Severe OA (Kellgren-Lawrence 3-4)<\/h3>\n\n<ul>\n<li>Regenerative options may still provide symptom relief but cartilage regeneration is less likely<\/li>\n<li>Cortisone for acute flares (judicious use)<\/li>\n<li>Serious discussion about surgical options<\/li>\n<li>Partial joint replacement may be appropriate for single-compartment disease<\/li>\n<li>Total joint replacement when function and quality of life are significantly impaired<\/li>\n<\/ul>\n\n<h2>When Surgery Makes Sense<\/h2>\n\n<p>Surgery is not a failure. For patients with end-stage OA who have genuinely exhausted conservative and regenerative options, joint replacement can restore function and eliminate pain in ways that no injection or supplement can match. The decision should be based on functional limitation and quality of life, not just imaging findings. Some patients with severe-looking X-rays function well, while others with moderate radiographic changes are significantly impaired.<\/p>\n\n<p>Red flags that suggest surgery should be considered sooner rather than later include: night pain that consistently disrupts sleep, inability to walk more than a few blocks, significant joint deformity with instability, and failure of multiple conservative treatments over 6-12 months.<\/p>\n\n<h2>The Bottom Line<\/h2>\n\n<p>Osteoarthritis treatment has evolved dramatically. The old model of &#8220;take Advil until you need a joint replacement&#8221; has been replaced by a spectrum of options that can modify disease progression, reduce inflammation at its source, and preserve joint function for years or even decades longer. The most important factors are starting early, combining multiple approaches, maintaining a healthy weight, staying active, and working with practitioners who understand the full range of available therapies.<\/p>\n\n<p>Regenerative medicine offers genuine promise for OA, particularly PRP and MSC therapy. But these are tools within a broader strategy, not magic bullets. The patients who do best are those who commit to the lifestyle foundations (exercise, diet, weight management) while using regenerative therapies to give their joints every biological advantage.<\/p>\n\n<h2>References<\/h2>\n\n<p>[1] Goldring MB, Otero M. Inflammation in osteoarthritis. <em>Curr Opin Rheumatol<\/em>. 2011;23(5):471-478. doi:10.1097\/BOR.0b013e328349c2b1. PMID: 21788902<\/p>\n\n<p>[2] Fransen M, McConnell S, Harmer AR, et al. Exercise for osteoarthritis of the knee: a Cochrane systematic review. <em>Br J Sports Med<\/em>. 2015;49(24):1554-1557. doi:10.1136\/bjsports-2015-095424. PMID: 26405113<\/p>\n\n<p>[3] \u00d8iestad BE, Juhl CB, Eitzen I, Thorlund JB. Knee extensor muscle weakness is a risk factor for development of knee osteoarthritis. A systematic review and meta-analysis. <em>Osteoarthritis Cartilage<\/em>. 2015;23(2):171-177. doi:10.1016\/j.joca.2014.10.008. PMID: 25450853<\/p>\n\n<p>[4] Crofford LJ. Use of NSAIDs in treating patients with arthritis. <em>Arthritis Res Ther<\/em>. 2013;15(Suppl 3):S2. doi:10.1186\/ar4174. PMID: 24267197<\/p>\n\n<p>[5] Machado GC, Maher CG, Ferreira PH, et al. Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials. <em>BMJ<\/em>. 2015;350:h1225. doi:10.1136\/bmj.h1225. PMID: 25828856<\/p>\n\n<p>[6] McAlindon TE, LaValley MP, Harvey WF, et al. Effect of intra-articular triamcinolone vs saline on knee cartilage volume and pain in patients with knee osteoarthritis: a randomized clinical trial. <em>JAMA<\/em>. 2017;317(19):1967-1975. doi:10.1001\/jama.2017.5283. PMID: 28510679<\/p>\n\n<p>[7] Evans JT, Walker RW, Evans JP, et al. How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up. <em>Lancet<\/em>. 2019;393(10172):655-663. doi:10.1016\/S0140-6736(18)32531-5. PMID: 30782341<\/p>\n\n<p>[8] Everts P, Onishi K, Jayaram P, et al. Platelet-rich plasma: new performance understandings and therapeutic considerations in 2020. <em>Int J Mol Sci<\/em>. 2020;21(20):7794. doi:10.3390\/ijms21207794. PMID: 33096812<\/p>\n\n<p>[9] Belk JW, Kraeutler MJ, Houck DA, et al. Platelet-rich plasma versus hyaluronic acid for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. <em>Am J Sports Med<\/em>. 2021;49(1):249-260. doi:10.1177\/0363546520909397. PMID: 32302218<\/p>\n\n<p>[10] Riboh JC, Saltzman BM, Yanke AB, et al. Effect of leukocyte concentration on the efficacy of platelet-rich plasma in the treatment of knee osteoarthritis. <em>Am J Sports Med<\/em>. 2016;44(3):792-800. doi:10.1177\/0363546515580787. PMID: 25925602<\/p>\n\n<p>[11] Mancuso P, Raman S, Glynn A, et al. Mesenchymal stem cell therapy for osteoarthritis: the critical role of the cell secretome. <em>Front Bioeng Biotechnol<\/em>. 2019;7:9. doi:10.3389\/fbioe.2019.00009. PMID: 30761299<\/p>\n\n<p>[12] Ha CW, Park YB, Kim SH, Lee HJ. Intra-articular mesenchymal stem cells in osteoarthritis of the knee: a systematic review of clinical outcomes and evidence of cartilage repair. <em>Arthroscopy<\/em>. 2019;35(1):277-288.e2. doi:10.1016\/j.arthro.2018.07.028. PMID: 30442514<\/p>\n\n<p>[13] Rabago D, Patterson JJ, Mundt M, et al. Dextrose prolotherapy for knee osteoarthritis: a randomized controlled trial. <em>Ann Fam Med<\/em>. 2013;11(3):229-237. doi:10.1370\/afm.1504. PMID: 23690322<\/p>\n\n<p>[14] Rabago D, Patterson JJ, Mundt M, et al. Dextrose prolotherapy for knee osteoarthritis: a randomized controlled trial. <em>Ann Fam Med<\/em>. 2013;11(3):229-237. doi:10.1370\/afm.1504. PMID: 23690322<\/p>\n\n<p>[15] Altman RD, Manjoo A, Fierlinger A, et al. The mechanism of action for hyaluronic acid treatment in the osteoarthritic knee: a systematic review. <em>BMC Musculoskelet Disord<\/em>. 2015;16:321. doi:10.1186\/s12891-015-0775-z. PMID: 26503103<\/p>\n\n<p>[16] Bellamy N, Campbell J, Robinson V, et al. Viscosupplementation for the treatment of osteoarthritis of the knee. <em>Cochrane Database Syst Rev<\/em>. 2006;(2):CD005321. doi:10.1002\/14651858.CD005321.pub2. PMID: 16625636<\/p>\n\n<p>[17] Messier SP. Obesity and osteoarthritis: disease genesis and nonpharmacologic weight management. <em>Med Clin North Am<\/em>. 2009;93(1):145-159. doi:10.1016\/j.mcna.2008.09.011. PMID: 19059026<\/p>\n\n<p>[18] Messier SP, Mihalko SL, Legault C, et al. Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial. <em>JAMA<\/em>. 2013;310(12):1263-1273. doi:10.1001\/jama.2013.277669. PMID: 24065013<\/p>\n\n<p>[19] Veronese N, Stubbs B, Noale M, et al. Adherence to a Mediterranean diet is associated with lower prevalence of osteoarthritis: data from the osteoarthritis initiative. <em>Clin Nutr<\/em>. 2019;38(4):1609-1614. doi:10.1016\/j.clnu.2018.08.028. PMID: 30224305<\/p>\n\n<p>[20] Daily JW, Yang M, Park S. Efficacy of turmeric extracts and curcumin for alleviating the symptoms of joint arthritis: a systematic review and meta-analysis of randomized clinical trials. <em>J Med Food<\/em>. 2016;19(8):717-729. doi:10.1089\/jmf.2016.3705. PMID: 27533649<\/p>\n\n<p>[21] Garc\u00eda-Coronado JM, Mart\u00ednez-Olvera L, Elizondo-Oma\u00f1a RE, et al. Effect of collagen supplementation on osteoarthritis symptoms: a meta-analysis of randomized placebo-controlled trials. <em>Int Orthop<\/em>. 2019;43(3):531-538. doi:10.1007\/s00264-018-4211-5. PMID: 30368550<\/p>\n\n<p>[22] Brosseau L, Taki J, Deber B, et al. Ottawa Panel evidence-based clinical practice guidelines for the management of osteoarthritis in adults who are obese or overweight. <em>Phys Ther<\/em>. 2011;91(9):1305-1338. doi:10.2522\/ptj.20100104. PMID: 21719637<\/p>\n\n<h2>Related Reading<\/h2>\n\n<ul>\n<li><a href=\"\/blog\/osteoarthritis-exercises\">Exercise for Osteoarthritis: The Best (and Worst) Movements for Joint Health<\/a><\/li>\n<li><a href=\"\/blog\/osteoarthritis-knee\">Knee Osteoarthritis: Symptoms, Staging, and Treatment Options<\/a><\/li>\n<li><a href=\"\/blog\/arthritis-in-hands\">Arthritis in Hands: Types, Symptoms, and Treatments That Preserve Function<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Osteoarthritis treatment has expanded well beyond painkillers and joint replacement. This guide covers the full spectrum, from lifestyle changes and physical therapy to regenerative injections like PRP and stem cells.<\/p>\n","protected":false},"author":1,"featured_media":6545,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","_regenerated_references":"","footnotes":""},"categories":[1006],"tags":[],"class_list":["post-5660","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-musculoskeletal-pain"],"_links":{"self":[{"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/posts\/5660","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/comments?post=5660"}],"version-history":[{"count":1,"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/posts\/5660\/revisions"}],"predecessor-version":[{"id":5804,"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/posts\/5660\/revisions\/5804"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/media\/6545"}],"wp:attachment":[{"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/media?parent=5660"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/categories?post=5660"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/regenerated.com\/blog\/wp-json\/wp\/v2\/tags?post=5660"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}