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4 Best ED treatment Clinics in Centennial, Colorado

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

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Centennial, CO

Erectile Dysfunction (ED) Treatment clinics in Centennial

Centennial is part of the Denver Tech Center regenerative cluster, with 13 providers advertising ED treatment. Local clinics typically offer a mix of low intensity shockwave therapy (LI-ESWT, often branded as GAINSWave), platelet rich plasma P-Shot injections, testosterone replacement therapy, and PDE5 inhibitors via in person or telehealth prescription. The regenerative angle appeals to patients looking past the pill for longer term vascular and tissue improvement, though LI-ESWT for ED remains off label in the United States with Emerging evidence. Colorado has broad telehealth permissibility for non controlled prescriptions, so Hims, Ro, and similar services set a low cost PDE5 floor around 20 to 100 dollars per month that any premium Centennial protocol should be benchmarked against. Underlying drivers like low testosterone, cardiometabolic disease, and pelvic floor dysfunction are worth ruling out before committing to a multi thousand dollar package, and a good Centennial clinic will start with labs and a cardiovascular risk assessment before upselling regenerative add ons.

4 Clinics

MD on staff

Colorado TRT

Centennial, CO

Colorado TRT, a hormone and peptide-therapy clinic in Littleton, specializes in testosterone-replacement therapy and hormone-replacement therapy alongside regenerative modalities including stem-cell …

  • PRP Therapy
  • Peptide Therapy
  • Erectile Dysfunction (ED) Treatment
  • Testosterone Replacement Therapy (TRT)
  • Hormone Replacement Therapy (HRT)

Denverurology

Centennial, CO

Denver Urology provides urological care for men and women, with a focus on erectile dysfunction treatment and testosterone replacement therapy. The practice specializes in hormone optimization for pa…

  • Erectile Dysfunction (ED) Treatment
  • Testosterone Replacement Therapy (TRT)
MD on staff

Littleton Wellness Center

Centennial, CO

Littleton Wellness Center in Littleton, Colorado, specializes in bioidentical hormone replacement therapy and peptide optimization for midlife and menopausal transitions. The practice offers individu…

  • PRP Therapy
  • Shockwave Therapy
  • Erectile Dysfunction (ED) Treatment
  • Hormone Replacement Therapy (HRT)

Harmony Hormone Therapy

Centennial, CO

Harmony Hormone Therapy, a hormone-optimization clinic in Centennial, specializes in bioidentical hormone replacement therapy and testosterone replacement therapy for men and women experiencing hormo…

  • Peptide Therapy
  • Erectile Dysfunction (ED) Treatment
  • Hormone Replacement Therapy (HRT)
  • Testosterone Replacement Therapy (TRT)
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Regulatory context

A note on Colorado's erectile dysfunction (ed) treatment rules.

The "other" category is a catchall for regenerative wellness modalities with inconsistent federal oversight. Red light therapy devices (photobiomodulation) have narrow FDA 510(k) clearances for acne, muscle pain, and wound healing, not systemic regeneration. Whole-body cryotherapy is NOT FDA-approved for any medical indication and received an FDA safety communication in July 2016 warning of asphyxiation, frostbite, and burn risks. Ozone therapy is NOT FDA-approved for any medical use and the FDA has stated ozone is a toxic gas with no known useful medical application. Condition-specific regenerative offerings (hair restoration with minoxidil or finasteride, ED care beyond PDE5 inhibitors and shockwave) have varying approval depending on route and drug source.

  • Colorado Medical Practice Act (C.R.S. Title 12, Art. 240)
    Defines scope of medical practice and delegation rules to nurses and medical assistants in outpatient and wellness settings.
  • Colorado Natural Health Consumer Protection Act (C.R.S. § 6-1-724)
    Permits non-licensed complementary and alternative health practitioners to offer services with required disclosures, excluding procedures that penetrate the skin.

The Colorado Medical Board investigates unlicensed medical practice, corporate practice violations, and false advertising by wellness clinics. Ozone and chelation clinics making disease-treatment claims have faced disciplinary action. The Department of Regulatory Agencies (DORA) consolidates oversight across medical, nursing, and pharmacy boards. Enforcement is moderate and complaint-driven. The Colorado Attorney General pursues deceptive health claims under the Colorado Consumer Protection Act.

Erectile Dysfunction (ED) Treatment in Centennial, answered.

Centennial clinics offer the full regenerative stack: low intensity shockwave therapy (LI-ESWT or GAINSWave) in typical 6 session protocols, P-Shot platelet rich plasma injections, testosterone replacement therapy when labs indicate hypogonadism, vacuum erection devices, and PDE5 inhibitors (sildenafil, tadalafil) via telehealth or in person prescription. PDE5 drugs are FDA approved. Shockwave for ED is FDA approved for other orthopedic uses but used off label for ED with emerging evidence.

In Centennial, premium clinics typically charge 4,000 to 7,500 dollars for a 6 session LI-ESWT protocol, mid market clinics run 2,500 to 6,000, and more affordable providers sit around 2,000 to 4,000. P-Shot injections range 1,500 to 3,000 per session. Telehealth PDE5 options like Hims, Ro, and Rex start at 20 to 100 dollars per month and set the practical price floor. TRT programs with labs and injections typically bundle at 150 to 350 per month.

No. Low intensity extracorporeal shockwave therapy (LI-ESWT) is not FDA approved for erectile dysfunction in the United States as of 2026. FDA cleared shockwave devices exist for orthopedic conditions like plantar fasciitis and kidney stones. Clinics that offer LI-ESWT for ED are using it off label. The evidence base is categorized as Emerging, with several randomized trials showing benefit in vasculogenic ED but inconsistent protocols and device variability across studies.

Yes. Colorado has broad telehealth permissibility for non controlled prescriptions. Hims, Ro, Rex, Henry Meds, and similar platforms prescribe sildenafil and tadalafil to Colorado residents after a brief online consult. Compounded formulations, including troche and combination doses, are available through state licensed compounding pharmacies. Controlled substances fall under the Ryan Haight Act, but PDE5 inhibitors are not controlled, so no in person visit is legally required for these medications.

Verify the prescriber on the Colorado medical board license lookup and the NPI registry. Ask about fellowship training in urology, men's health, or sexual medicine. Request the evidence base for any proposed treatment, especially LI-ESWT and P-Shot. Check the FDA warning letter database for clinic or provider names. Be cautious of clinics that push large prepaid packages, require bundling, or promise guaranteed outcomes. A reputable Centennial clinic will run bloodwork and cardiovascular risk assessment first.

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