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Optimize U – Jeffersonville
MD on staff OIG Cleared

Optimize U – Jeffersonville

1401 Veterans Pkwy Suite 700, Clarksville, IN 47129, USA, 47129 Clarksville, IN
5.00

About this clinic

Optimize U – Jeffersonville, a hormone optimization clinic in Clarksville, specializes in peptide therapy and hormone replacement therapy alongside IV therapy protocols. The practice begins with comprehensive lab work to establish a baseline and inform individualized treatment plans. Offerings include peptide and hormone treatments targeting weight management, energy, and age-related decline, supported by IV nutrient therapy and infrared-sauna protocols for detoxification and recovery. The clinic positions hormone optimization and peptide therapy as the foundation of its approach, with aesthetic services available as a secondary offering. Treatment decisions are guided by lab results rather than a one-size-fits-all protocol.

Treatments offered

Peptide Therapy

Experimental evidence

Hormone Replacement Therapy (HRT)

Strong evidence

IV Therapy

Insufficient evidence

Red Light Therapy

Emerging evidence

Contact information

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1401 Veterans Pkwy Suite 700, Clarksville, IN 47129, USA
47129 Clarksville, IN
Website

Office hours

Monday – Friday
9am – 5pm
Saturday – Sunday
Closed

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Patient reviews

5.00

Based on 61 Google reviews

5 ★
4 ★
3 ★
2 ★
1 ★

I absolutely love this facility and what they have to offer! They customize each treatment for you, not just a “cookie cutter” dosage. I have worked with both Jessica and Rachel and both are amazing! They take their time explaining their recommendations and the details. Highly recommend, especially if you are wondering where you are at as you start to transition into the perimenopause phase.

Lorna Johnson · January 20th, 2026

Great place, knowledgeable staff, Jessica Mattis was great too time to ask real questions, make sure that we were on the same page, and that I was getting the right treatments for me. That have been professionals, taking care of a very particular patient. I’ve been getting treated for 10 years and this is one of the best places I’ve had handle me.

Patrick casto · December 30th, 2025

I've been a customer of Optimize U in Jefferson Indiana for almost a year. The staff is very knowledgeable about the peptides and services they offer. I'm on a TRT program and I feel great. The monthly payment (investment in myself) is reasonable and well worth it. My practitioner Dylan Martin is awesome. If you've been thinking about trying the services they offer, make an appointment and start feeling better soon.

E. B. · January 6th, 2026

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