Skip to content
Homepage
Clinic directory

12 Best Lyme Disease Treatment Clinics in New York, New York

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

  • No results found.
  • No results found.

New York, NY

Lyme Disease Treatment clinics in New York

New York is the densest healthcare market in the country, with academic powerhouses alongside boutique integrative clinics in Manhattan and Brooklyn. Lyme disease care remains one of the most contested areas in medicine. Local options range from infectious disease specialists following IDSA guidelines to Lyme-literate practitioners following ILADS protocols, with integrative clinics offering IV nutrient therapy, off-label hyperbaric oxygen, and ozone as adjuncts.

Acute Lyme disease is effectively treated with short-course doxycycline, amoxicillin, or cefuroxime with Strong evidence. The controversy centers on persistent or chronic symptoms after treatment. Mainstream guidelines from the Infectious Diseases Society of America do not recommend prolonged antibiotics for post-treatment Lyme disease syndrome. ILADS guidelines take a different position, and a parallel Lyme-literate provider community supports longer courses. IV nutrient, HBOT, and ozone therapies have Insufficient evidence for Lyme specifically.

The clinics listed below represent different philosophies of care.

12 Clinics

Verified MD on staff

hol+

New York, NY

hol+, a functional medicine clinic in New York, specializes in root-cause assessment and treatment of chronic conditions, hormone imbalance, and digestive dysfunction. The practice offers comprehensi…

  • IV Therapy
  • Lyme Disease Treatment
  • Peptide Therapy
  • Hormone Replacement Therapy (HRT)
MD on staff

RegenPain

New York, NY

RegenPain, a musculoskeletal and pain-management clinic in New York, specializes in platelet-rich plasma therapy for joint and musculoskeletal conditions. The practice focuses on nonsurgical approach…

  • PRP Therapy
  • Arthritis Treatment
  • Lyme Disease Treatment
  • Stem Cell Therapy
MD on staff

Firshein Center

New York, NY

Firshein Center, an integrative-medicine practice in New York, offers IV therapy and platelet-rich plasma injections as core regenerative modalities for patients pursuing longevity and age-related op…

  • PRP Therapy
  • IV Therapy
  • Arthritis Treatment
  • Lyme Disease Treatment
  • Migraine Treatment
MD on staff

Doctorpaulvin

New York, NY

Doctorpaulvin, an IV therapy clinic in New York, specializes in intravenous nutrient protocols including NAD+ infusions and vitamin IV therapy alongside peptide therapy. The clinic takes a functional…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • Lyme Disease Treatment
  • Peptide Therapy
MD on staff

Patients Medical PC, Functional and Holistic Medicine

New York, NY

Patients Medical PC, a functional and holistic medicine clinic in Manhattan, offers a broad spectrum of regenerative and supportive modalities including stem-cell therapy, peptide and hormone optimiz…

  • Ozone Therapy
  • Multiple Sclerosis (MS) Treatment
  • Ketamine Therapy
  • Arthritis Treatment
  • Chelation Therapy

Comprehensive Pain Management

New York, NY

Comprehensive Pain Management, in New York, specializes in pain treatment through ketamine infusion, nerve blocks, trigger-point injections, and spinal-cord stimulation alongside epidural steroid inj…

  • Ketamine Therapy
  • Lyme Disease Treatment

VitalGate

New York, NY

VitalGate, a functional and integrative medicine clinic in New York, combines acupuncture with regenerative and supportive-medicine modalities including Ozone Therapy, Peptide Therapy, Red Light Ther…

  • Ozone Therapy
  • Oxygen Therapy
  • Multiple Sclerosis (MS) Treatment
  • Arthritis Treatment
  • Lyme Disease Treatment
MD on staff

Hyperbaric Medical Solutions

New York, NY

Hyperbaric Medical Solutions, a regenerative medicine clinic in New York, offers hyperbaric oxygen therapy (HBOT), platelet-rich plasma therapy (PRP), and IV therapy alongside ketamine therapy and lo…

  • PRP Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy
  • Ketamine Therapy
MD on staff

LEDA Medical

New York, NY

LEDA Medical, a clinic in New York specializing in autoimmune and inflammatory neurological conditions, offers IV Therapy and NAD IV Therapy alongside comprehensive diagnostic evaluation. The practic…

  • IV Therapy
  • Arthritis Treatment
  • Lyme Disease Treatment
  • Migraine Treatment
  • NAD IV Therapy
MD on staff

Healing Arts NYC

New York, NY

Healing Arts NYC, an integrative-medicine clinic in New York, combines regenerative modalities with detoxification protocols and supportive therapies. The clinic offers stem-cell therapy alongside oz…

  • Ozone Therapy
  • Arthritis Treatment
  • Lyme Disease Treatment
  • Red Light Therapy
  • Peptide Therapy
MD on staff

Raphael Kellman

New York, NY

Raphael Kellman, a functional medicine clinic in New York, specializes in integrative assessment and treatment of chronic illness, with particular attention to microbiome-related dysfunction. The pra…

  • Ozone Therapy
  • IV Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
  • Lyme Disease Treatment
MD on staff

Halcyon Life

New York, NY

Halcyon Life, a hyperbaric oxygen therapy center in New York, offers Hyperbaric Oxygen Therapy (HBOT) as its primary treatment modality. HBOT involves breathing pure oxygen in a pressurized chamber, …

  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy
  • Multiple Sclerosis (MS) Treatment
  • Lyme Disease Treatment
  • Migraine Treatment
15 30 50 results per page

Regulatory context

A note on New York's lyme disease treatment rules.

The "other" category is a catchall for regenerative wellness modalities with inconsistent federal oversight. Red light therapy devices (photobiomodulation) have narrow FDA 510(k) clearances for acne, muscle pain, and wound healing, not systemic regeneration. Whole-body cryotherapy is NOT FDA-approved for any medical indication and received an FDA safety communication in July 2016 warning of asphyxiation, frostbite, and burn risks. Ozone therapy is NOT FDA-approved for any medical use and the FDA has stated ozone is a toxic gas with no known useful medical application. Condition-specific regenerative offerings (hair restoration with minoxidil or finasteride, ED care beyond PDE5 inhibitors and shockwave) have varying approval depending on route and drug source.

  • New York Education Law Article 131 (Practice of Medicine)
    Defines practice of medicine and strictly enforces corporate practice restrictions for medical spas.
  • New York Business Corporation Law § 1503
    Requires professional service corporations providing medical services to be owned exclusively by licensed physicians.
  • NYS Department of Health Office of Professional Medical Conduct
    Investigates physician misconduct including inappropriate delegation at medical spas.

New York is one of the strictest enforcement states. The Office of Professional Medical Conduct (OPMC) has issued public guidance and pursued disciplinary action against medical spas for corporate practice violations, inappropriate RN or PA delegation, and false advertising of unapproved therapies. Ozone therapy faces heavy scrutiny, and clinics making cancer, Lyme, or autoimmune treatment claims have faced OPMC action and Attorney General consumer protection lawsuits. The NY AG pursues deceptive health claims aggressively under General Business Law Article 22-A.

Lyme Disease Treatment in New York, answered.

A classic erythema migrans rash after a known tick exposure in an endemic area supports empiric treatment, even before serology. For non-rash presentations, two-tier testing with ELISA and Western blot, or newer modified two-tier algorithms, is standard. Doxycycline is first-line for most adults, with amoxicillin or cefuroxime as alternatives. A typical course is 10 to 21 days. Early treatment generally produces excellent outcomes.

Chronic Lyme is a contested concept. Post-treatment Lyme disease syndrome refers to persistent fatigue, pain, or cognitive symptoms after documented Lyme disease and standard treatment, and is recognized in IDSA guidelines. Broader chronic Lyme labels used in the Lyme-literate community often include patients without prior documented infection. Evidence for long-course antibiotics in this broader group is limited and controversial. Patients should understand both frameworks before choosing a care path.

The Infectious Diseases Society of America guidelines emphasize standard short-course antibiotics and do not recommend prolonged therapy for post-treatment symptoms. The International Lyme and Associated Diseases Society supports individualized and sometimes extended treatment courses. Both groups publish detailed guidelines. Patients with complex cases often benefit from understanding both positions and, where possible, obtaining opinions from clinicians on each side.

Evidence for hyperbaric oxygen, ozone, and IV nutrient therapy specifically for Lyme disease is Insufficient. These are commonly offered in integrative and Lyme-literate settings. Some patients report symptom improvement, but high-quality trials are lacking. Patients considering these options should discuss realistic expectations, cost, and how outcomes will be measured, and should not abandon basic diagnostic workup or evidence-based care in favor of them.

If you have an acute tick exposure or rash, an infectious disease or primary care evaluation is appropriate and usually straightforward. For persistent symptoms, many patients seek care from Lyme-literate practitioners, ideally alongside an infectious disease opinion. Integrative clinics can support symptom management but are not a substitute for diagnostic clarity. The listings flag philosophy of care so patients can make informed choices.

Filters

Rating

Treatments

Advanced Therapies
Chronic, Immune & Hormonal 1
Digestive & Respiratory
IV & Infusion
Pain & Musculoskeletal
Skin & Aesthetics
Mental Health & Neurology