Skip to content
Homepage
Clinic directory

5 Best Stem Cell Therapy Clinics in Oklahoma City, Oklahoma

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

  • No results found.
  • No results found.

Oklahoma City, OK

Stem Cell Therapy clinics in Oklahoma City

Oklahoma City supports a regenerative medicine market shaped by both private clinics and regional academic medicine. Local referral networks run through OU Medical Center, Integris Baptist, and Mercy Health, and stem cell practice in the area spans Nichols Hills, Edmond border, and the Medical District. Patient demand splits across three buckets: orthopedic injections for active adults and aging athletes, neurological and autoimmune protocols marketed to longevity-focused patients, and IV-based allogeneic products offered by private wellness clinics. The FDA classifies most stem cell injections for orthopedic, neurological, or longevity use as investigational biologics under 21 CFR Part 1271, meaning they require either a Biologics License or an active Investigational New Drug authorization. Autologous bone marrow and adipose products may qualify as Section 361 when minimally manipulated and used for homologous function. Oklahoma regulates physician practice through the State Board of Medical Licensure and Supervision. There is no Oklahoma-specific stem cell statute, so federal 21 CFR Part 1271 rules apply. The 3 Oklahoma City clinics listed below have been reviewed against our vetting criteria, including federal NPI lookup, OIG exclusion screening, and Oklahoma Board of Medical Licensure licensure checks.

5 Clinics

MD on staff

Oklahoma Pain Treatment Centers - Blake Christensen D.O.

Oklahoma City, OK

Oklahoma Pain Treatment Centers, led by Blake Christensen D.O., offers regenerative and conventional pain-management services in Oklahoma City. The practice specializes in bone-marrow stem-cell conce…

  • Arthritis Treatment
  • Stem Cell Therapy
MD on staff

Oklahoma Pain Center

Oklahoma City, OK

Oklahoma Pain Center, a regenerative-medicine practice in Oklahoma City, specializes in stem-cell therapy, platelet-rich plasma injections, and ketamine infusion therapy for chronic musculoskeletal a…

  • PRP Therapy
  • Ketamine Therapy
  • Arthritis Treatment
  • Stem Cell Therapy

Rejuvenate Health & Wellness Lounge

Oklahoma City, OK

Rejuvenate Health & Wellness Lounge, an IV therapy clinic in Oklahoma City, offers a comprehensive array of regenerative and supportive-medicine treatments. The practice features IV nutrient therapy,…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • Shockwave Therapy
MD on staff

Ethos Wellness Center

Oklahoma City, OK

Ethos Wellness Center, a regenerative-medicine clinic in Oklahoma City, is led by Joseph Palmeri, MD. The practice focuses on regenerative therapies and preventative care, offering individualized tre…

  • IV Therapy
  • Acne Treatment
  • Arthritis Treatment
  • Red Light Therapy
  • Peptide Therapy
MD on staff

Orthobiogen

Oklahoma City, OK

Orthobiogen, a Regenerative Medicine Clinic in Oklahoma City, specializes in platelet-rich plasma therapy and stem-cell treatment for musculoskeletal and joint conditions. The practice offers platele…

  • PRP Therapy
  • Arthritis Treatment
  • Stem Cell Therapy
15 30 50 results per page

Regulatory context

A note on Oklahoma's stem cell therapy rules.

Oklahoma cellular therapy is governed by 21 CFR Part 1271. Section 361 covers minimally manipulated HCT/Ps used for homologous use without premarket approval. Section 351 covers products that are more than minimally manipulated, used non-homologously, or combined with another article, and these require an IND for clinical use or a BLA for marketing. Most stem cell, stromal vascular fraction, and exosome therapies marketed in Oklahoma for orthopedic, neurologic, and longevity indications are Section 351 biologics that lack FDA approval. Oklahoma's regulatory environment relies on federal law and the Oklahoma Allopathic Medical and Surgical Licensure and Supervision Act.

  • Oklahoma Allopathic Medical and Surgical Licensure and Supervision Act, 59 OS Section 480 et seq
    Establishes MD licensure and discipline through the Oklahoma State Board of Medical Licensure and Supervision.
  • Oklahoma Osteopathic Medicine Act, 59 OS Section 620 et seq
    Establishes DO licensure and discipline through the Oklahoma State Board of Osteopathic Examiners.
  • Oklahoma Pharmacy Act, 59 OS Section 353 et seq
    Regulates compounding pharmacies aligned with federal 503A and 503B standards.

The FDA has corresponded with Oklahoma providers offering cellular therapies. The Oklahoma State Board of Medical Licensure and Supervision and the Board of Osteopathic Examiners have disciplined physicians for unprofessional conduct including misleading regenerative medicine advertising. The Oklahoma Attorney General can pursue deceptive marketing under the Oklahoma Consumer Protection Act. Oklahoma's smaller market means enforcement is less frequent than in larger states, but federal warning letters apply nationally.

Stem Cell Therapy in Oklahoma City, answered.

Most stem cell therapies at private Oklahoma City clinics are not FDA-approved. The FDA has approved certain hematopoietic stem cell products for blood and immune disorders, but stem cell injections for orthopedic, neurological, or longevity use are generally investigational. They require a Biologics License or an active Investigational New Drug authorization, or they must qualify as Section 361 minimally manipulated and homologous-use products under 21 CFR Part 1271. Oklahoma regulates physician practice through the State Board of Medical Licensure and Supervision.

In the Oklahoma City metro, single-joint autologous bone marrow or adipose injections typically run $4,000 to $12,000 per session. Systemic IV protocols using allogeneic umbilical cord or Wharton's jelly products range $8,000 to $20,000, and full multi-session protocols can reach $15,000 to $40,000. Exosome add-ons range $3,500 to $7,500. Insurance rarely covers these treatments because the FDA classifies most protocols as investigational.

Autologous stem cells come from your own body, usually harvested from bone marrow aspirate or adipose tissue and reinjected the same day. When minimally manipulated and used for homologous function, they often fall under FDA Section 361, which does not require pre-market approval. Allogeneic stem cells come from a donor source, most commonly umbilical cord blood or Wharton's jelly, and are generally classified as Section 351 biologics that require an active Investigational New Drug authorization. Oklahoma City clinic offerings span both categories, so ask which classification applies before treatment.

Yes. Research programs at OU Medical Center, Integris Baptist, and Mercy Health periodically run FDA-authorized stem cell trials across orthopedics, neurology, cardiology, and oncology. Search clinicaltrials.gov and filter by Oklahoma City or the broader metro to see active recruiting studies. Trial participation is typically low-cost or free compared to commercial protocols and includes structured follow-up with imaging and lab monitoring.

Verify physician licensure through the Oklahoma Board of Medical Licensure and confirm the clinic's NPI number through the NPPES registry. Check the FDA warning letter database for the clinic name and the HHS Office of Inspector General exclusion list. Ask whether the treatment is Section 361 or Section 351, whether the clinic operates under an Investigational New Drug authorization for allogeneic or expanded products, and whether adverse events are tracked. Ask specifically about compliance with federal 21 CFR 1271.

Filters

Rating

Treatments

Advanced Therapies 1
Chronic, Immune & Hormonal
Digestive & Respiratory
IV & Infusion
Pain & Musculoskeletal
Skin & Aesthetics
Mental Health & Neurology