Evidence-based regenerative and functional medicine
We read the research.
You make better decisions.
Stem cells, peptides, NAD+, HBOT, and the functional medicine everyone is arguing about. 480+ guides built from peer-reviewed studies, written for patients and practitioners who want the mechanism, the evidence, the real cost, and the risk. Not the marketing.
No clinic, supplement brand, or telehealth company pays us for a kinder verdict.

The standard we hold every guide to
Named sources, not vague claims
We cite the journal, the authors, the year, and the sample size. If a claim rests on a single mouse study, we say so on the page, in the same sentence.
Evidence grading on every treatment
Each therapy opens with a plain rating for how strong the human evidence actually is, from well-established to experimental, before any of the hope.
Honest about what does not work
We publish the disappointing trials too. No clinic, supplement brand, or telehealth company can buy a warmer verdict, because none of them pay us.
The guides people read first
Start where the questions are loudest. Each guide walks through how the treatment works, who it actually helps, what it realistically costs, and where the evidence is still thin.

Peptide Therapy
BPC-157, TB-500, and the rest: what has real human data, what is still animal work, and what the compounding rules changed in 2024.
- NAD+ IV Therapy Energy, aging, addiction recovery: where the infusion story holds and where it thins out. EXPERIMENTAL
- Stem Cell Therapy Knees, autoimmunity, anti-aging clinics: which uses have trials behind them. PROMISING
- Hyperbaric Oxygen Therapy Approved uses, long-COVID studies, and the off-label claims to be careful with. PROMISING
- Ketamine Therapy Treatment-resistant depression, dosing, and the gap between clinic and evidence. WELL-ESTABLISHED
- TRT Who genuinely benefits, the cardiovascular data, and how to read your own labs. WELL-ESTABLISHED
- MCAS Mast cell activation: diagnosis controversy, what the criteria actually require, and treatment options. EXPERIMENTAL

Start with your body, not the buzzword
If you came here because of a diagnosis that took years to get a name, or because you were told there was nothing there, begin here. We map the treatments being tried for each condition and grade the evidence behind each one, so you can tell a real option from a hopeful one.
- Autoimmune & InflammatoryHashimoto’s, RA, MS, Crohn’s
- Gut Health & DigestiveSIBO, Leaky Gut, Histamine, Celiac
- Musculoskeletal & PainFibromyalgia, Chronic Pain, OA, Migraine
- Fatigue & Recovery SyndromesBrain Fog, CFS, Long COVID, SFN
- Toxin & Environmental ExposureLyme, Mold/CIRS, Heavy Metals
- Women’s Health & MenopauseMenopause, HRT, POTS, EDS
- Skin ConditionsEczema, Psoriasis, Vitiligo, Lichen Sclerosus
- Respiratory & Post-ViralLong COVID, Post-Viral Fatigue, Asthma
Or start with a treatment you are weighing
Considering a specific therapy? Read the mechanism, the human trials, the realistic cost, and the safety profile before you sit in a consult or spend a dollar.
- Regenerative MedicineStem Cells, PRP, Exosomes, Prolotherapy
- Peptides & Hormone OptimizationBPC-157, HRT, TRT
- IV & Infusion TherapyNAD+, Chelation, Glutathione
- Oxygen & Energy TherapiesHBOT, Ozone, Red Light, Cryotherapy
- Neuromodulation & Brain HealthNeurofeedback, TMS, Biofeedback
- Ketamine & Psychedelic TherapyKetamine, Psychedelics, LDN

How we grade the evidence
Every treatment page opens with a grade, before the hope. The grade is never a traffic light. There is no red, amber, or green doing quiet marketing work. It is one evergreen mark that fills further as the human evidence gets stronger, so it reads the same whether or not you see color.
- WELL-ESTABLISHED Large, repeated human trials agree.
- PROMISING Early human data looks good but is not settled.
- EXPERIMENTAL Mostly lab or animal work so far.
- NOT SUPPORTED The studies were done and it did not hold up.
Built for two hard jobs
For patients
You should not be reading trial abstracts at 2am
You already do the work no one asked you to do: cross-checking a forum claim against a study you half understand, alone, when you should be asleep. We do that reading in daylight and hand you the part that changes your decision, in plain language, with the source attached.
For practitioners
Built to survive a second opinion
Print any guide and it holds up when your patient Googles it in the parking lot, and when a colleague pushes back. We link the primary literature, note the sample sizes, and flag where a claim outruns its evidence, so you can hand it over without a caveat.
What we will tell you that a clinic won’t
We take no money from clinics, supplement brands, or telehealth companies, which is why we can write the sentence they cannot. That a popular peptide has almost no human data. That an expensive infusion is unlikely to touch your condition. That the trial everyone quotes had nineteen people in it. Being useful sometimes means being the ones who disappoint you, and we would rather you learn it here than after the invoice.
Updates
One email when the evidence actually changes
No weekly filler and no drip campaign. Once or twice a month at most, and only when a real trial lands, a guide gets a new grade, or we have to walk back something we published.
No data selling. Unsubscribe in one click.
480+ guides. One standard. No agenda.
Read the research without reading every study yourself. Start with the guide for your condition or the treatment you are weighing, and see exactly where the evidence stands today.
Peer-reviewed sources. Graded evidence. Updated as the science moves.