REVÄŞV Regenerative Medicine
- Stem Cell Therapy
- Exosome Therapy
- PRP Therapy
Read the Exosome Therapy guide for the educational context behind this treatment category.
United States
This is the national page for exosome therapy on Regenerated.com, listing clinics across the United States that record the treatment. Exosome therapy, also called exosome treatment, exosome injections, exosome IV or extracellular vesicle (EV) therapy, uses tiny membrane-bound particles that cells release to carry proteins, lipids and RNA to other cells. Most products sold to clinics are processed from mesenchymal stem cells grown from donated umbilical cord, placental or amniotic tissue, then filtered and frozen or freeze dried. Clinics give them by IV infusion, by injection into a joint or tendon, on the scalp, on the skin after microneedling or laser, or by nebulizer. Physicians in regenerative, sports and orthopedic medicine, dermatologists, aesthetic physicians, nurse practitioners and naturopathic physicians offer them, and people often compare them with platelet-rich plasma (PRP), stem cell therapy, PRF and hyaluronic acid injections.
The evidence for exosome therapy is early. Laboratory and animal research is active, and a widely cited 2020 review in Science by Raghu Kalluri and Valerie LeBleu describes how exosomes move signals between cells, but human trials are small and mostly early phase. No exosome product is FDA approved for any use in the United States. The FDA regulates these products as biologics that need an approved application or an investigational new drug (IND) study, and in December 2019 it issued a public safety notification after reports of serious adverse events in patients who received unapproved exosome products. Uses for joint pain, hair loss, skin aging, long COVID, autoimmune and neurologic conditions remain investigational, and the International Society for Extracellular Vesicles has published standards because products vary widely in content and purity.
People who consider exosome therapy are usually adults with a diagnosed condition that standard care has not resolved, or adults seeking cosmetic skin or scalp treatment, who accept that evidence is limited and that they will pay cash. People with active cancer, an active infection, pregnancy, a weakened immune system, or a condition that has an established treatment they have not yet tried are usually told to wait or speak with their specialist first. A clinical trial listing is often a better route for serious or progressive disease.
Supply is spread unevenly across the country. Exosome therapy is offered in regenerative and orthopedic physician practices, dermatology and medical aesthetics clinics, IV infusion suites and wellness studios, while university hospital programs mainly offer it inside research studies. Listings tend to concentrate in large Sun Belt metros, especially South Florida, Southern California, Texas and Arizona, along with the New York area, and many patients travel for a visit. Ask how follow up will work after you return home.
Before booking anywhere, ask who examines you, who administers the product, and which physician supervises the clinic, and check each license yourself with the state board. Ask exactly what product you will receive, what tissue it came from, which laboratory processed it, how it was tested for sterility and identity, and whether it is given under an FDA IND. Ask for written disclosure of risks such as infection, allergic or immune reactions, injection site problems and the unknowns of an unapproved biologic. A clear quote itemizes the consultation, imaging or labs, the product, any procedure fee and follow up.
This national list is not for sale. Organic order is never paid ranking, Featured slots are labeled and capped, and Verified means the clinic completed credential checks, not that it spent money. Regenerated.com is free for patients, and inclusion in the directory is not an endorsement. Use the state hubs below the list to build a shortlist closer to you.
For product sources, regulation and terms in more depth, read the exosome therapy guide. Two short explainers cover how listings work here: How to read a Regenerated city hub and Featured vs Verified vs organic.