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22 Best Ketamine Therapy Clinics in Phoenix, Arizona

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Phoenix, AZ

Ketamine Therapy clinics in Phoenix

Searching for a ketamine clinic in AZ can mean comparing Phoenix offices with practices across the surrounding metro. This page currently lists 22 clinics offering ketamine therapy for the Phoenix area. Within Phoenix, options include the Camelback Corridor and Biltmore area, Arcadia, and Desert Ridge near Loop 101. Practices also serve patients from Scottsdale, Paradise Valley, Tempe, and Chandler, so confirm the treatment address rather than relying on a Phoenix service label. State Route 51 connects central Phoenix with Loop 101 near Desert Ridge, making the route relevant when arranging repeat visits and a ride home.

Ketamine therapy in Phoenix is available in psychiatric offices and dedicated infusion suites. For intravenous treatment, ask which nurse or anesthesia professional administers and monitors the medication and which licensed prescriber oversees the psychiatric plan. Nasal esketamine is a related medication with a distinct protocol and is given only in certified treatment settings, so ask whether the office is one. Ketamine paired with talk therapy adds a psychotherapy component. Visits generally include dosing in a quiet room and monitored recovery before discharge, with doses individualized and maintenance considered according to response. A first visit usually includes a psychiatric and medical history review, current medication check, and blood pressure screening, with follow up built around symptom tracking rather than a fixed number of sessions.

Before booking anywhere in the Phoenix area, ask who prescribes and who administers each dose, what credentials and supervision are in place, and where the medication is sourced. Ask for the risks in writing, what the plan is if symptoms do not improve, and for a written quote that separates assessment, medication, administration, monitoring, and follow up visits. Intravenous ketamine for depression is off label and commonly cash pay; evidence for approaches marketed as microdosing remains limited. Confirm transportation requirements and when driving can resume before choosing an appointment across the Valley.

How this Phoenix listing is ordered matters too: organic order on Regenerated.com is not sold, Featured placements are labeled and capped, and Verified means credential checks rather than how much a provider pays. Regenerated.com is free for patients to use, and appearing in it is not an endorsement of any clinic or treatment.

For the mechanism and broader evidence behind ketamine therapy, see the national ketamine therapy hub. For more on how this directory works, read How to read a Regenerated city hub and Featured vs Verified vs organic.

22 Clinics, showing page 2 of 2

Redemption Psychiatry TMS
(5) Physician reported in record

Redemption Psychiatry TMS

Phoenix, AZ

Redemption Psychiatry TMS, an outpatient psychiatric practice in Phoenix, specializes in treatment-resistant depression using Ketamine Therapy and Transcranial Magnetic Stimulation (TMS). The clinic …

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
The Ketamine Clinic & Wellness
(4) Physician status unknown

The Ketamine Clinic & Wellness

Phoenix, AZ

The Ketamine Clinic & Wellness, located in Phoenix, specializes in ketamine therapy for treatment-resistant depression, anxiety, and PTSD, alongside NAD+ infusions and IV therapy for supportive care.…

  • IV Therapy
  • Ketamine Therapy
  • NAD IV Therapy
Rooted Alma
(1) Physician reported in record

Rooted Alma

Phoenix, AZ

Rooted Alma Therapy, a ketamine-assisted psychotherapy clinic in Phoenix, offers integrative treatment for trauma, anxiety, and depression. The practice is led by Shereen Breuer, MSW, LCSW, CCTP, a l…

  • Ketamine Therapy
  • Psychedelic Therapy
Vogue Recovery Center
(136) Physician reported in record

Vogue Recovery Center

Phoenix, AZ

Vogue Recovery Center, a ketamine-assisted therapy clinic in Phoenix, specializes in addiction treatment and medical detoxification using ketamine as a clinical modality alongside comprehensive inpat…

  • Ketamine Therapy
(7) Physician reported in record

AwarePsych

Phoenix, AZ

AwarePsych, a ketamine and psychedelic-assisted therapy clinic in Phoenix, specializes in ketamine therapy for treatment-resistant depression, anxiety, and PTSD alongside peptide protocols. The clini…

  • Ketamine Therapy
  • Peptide Therapy
(719) Physician reported in record

Serenity Mental Health Centers

Phoenix, AZ

Serenity Mental Health Centers, a ketamine and psychedelic-assisted therapy clinic in Phoenix, specializes in Ketamine Therapy and Transcranial Magnetic Stimulation (TMS) for treatment-resistant depr…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Headlight Mental Healthcare
(8) Physician status unknown

Headlight Mental Healthcare

Phoenix, AZ

Headlight Mental Healthcare, a Ketamine Therapy Clinic in Phoenix, specializes in ketamine-assisted psychotherapy for treatment-resistant depression, anxiety, PTSD, and related mood and trauma condit…

  • Ketamine Therapy
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Regulatory context

A note on Arizona's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • Arizona Psilocybin Research Grant (SB 1726, 2023)
    Allocated $5 million for whole-mushroom psilocybin clinical research; does not create a therapeutic access framework.
  • Arizona Controlled Substances Act
    Mirrors federal scheduling outside the research grant program.

Arizona enforces federal DEA scheduling and has not decriminalized psilocybin or MDMA. The Arizona Medical Board and Arizona Board of Osteopathic Examiners oversee prescribing conduct. DEA enforcement on ketamine clinics focuses on compounding sources, diversion, and billing fraud. Ryan Haight Act rules apply to telehealth ketamine prescriptions, with DEA flexibilities extended through 2025.

Sources: dea.gov · azleg.gov · azmd.gov · pharmacy.az.gov

Ketamine Therapy in Phoenix, answered.

Ketamine therapy uses a dissociative anesthetic, sometimes alongside talk therapy, under clinical supervision. Esketamine nasal spray is a related but distinct medication with its own treatment requirements. The national hub explains mechanisms and evidence; this Phoenix page helps compare local providers and travel needs beyond a general web search. Organic order is not sold, Featured slots are labeled and capped, and Verified means credential checks, not spending. Regenerated.com is free for patients, and inclusion is not an endorsement.

Phoenix providers typically monitor vital signs before, during, and after dosing in an infusion suite or psychiatric office. Treatment should follow an assessment reviewing the diagnosis and response to standard antidepressants or therapy. Research supports short term symptom improvement for some adults with treatment resistant depression, but response and durability vary. Clinicians should track mood and functioning over subsequent visits, adjust the plan based on response, and coordinate with your ongoing mental health care.

Short term effects can include dissociation, elevated blood pressure, nausea, sedation, and temporary changes in perception, which is why monitoring continues through recovery. Breathing problems can occur. A Phoenix provider should disclose risks in writing and explain how staff respond if something goes wrong. Ask about misuse potential, bladder symptoms with repeated use, and how the clinic documents your response over time. Arrange a ride home and obtain written instructions about driving and whom to contact afterward.

Adults with depression that has not improved after adequate standard treatment may be considered following a psychiatric and medical evaluation. Evidence for anxiety and other conditions is less established, so a diagnosis alone does not establish suitability. Pregnancy, uncontrolled blood pressure, certain cardiovascular conditions, or active psychosis may lead clinicians to defer treatment or recommend alternatives. A Phoenix consultation should review medications and substance use, explain the recommendation, and consider how ongoing care will be coordinated.

Cost depends on the formulation, setting, staffing, and number of visits a plan requires, which is why this page does not publish an average. Intravenous ketamine for depression is largely cash pay, while esketamine, evaluations, or accompanying therapy may be covered depending on your insurance plan and network. Ask for a written quote itemizing assessment, medication, administration, monitoring, and follow up, including separately billed services. Confirm coverage and any prior authorization directly with your insurer before booking.

Ketamine protocols vary by formulation and individual response, so a Phoenix provider should outline an initial treatment phase followed by a structured check-in on mood and functioning rather than promising results by a fixed number of visits. Ask upfront how progress is measured, who reviews the response, and what happens if symptoms have not shifted by that review point. Maintenance should depend on documented benefit and tolerability, with discussion of stopping or changing treatment and arranging ongoing support.

Ketamine can be legally prescribed, but intravenous use for depression is off label, meaning it is not FDA approved for that purpose. Esketamine nasal spray has specific FDA approved depression indications and requires a certified treatment setting. Verify the prescriber's active license through the Arizona Medical Board for MDs, the Arizona osteopathic board for DOs, or the Arizona State Board of Nursing for nurse practitioners. Check disciplinary information and ask who monitors dosing, supervises care, and handles emergencies.

Research into ketamine for bipolar depression and substance use disorders is ongoing, but evidence remains more limited than for treatment resistant unipolar depression. Long term benefits and risks remain uncertain, and ketamine itself has misuse potential. Anyone with bipolar disorder or a substance use history should raise it during screening because it may change the recommendation. Ask how clinicians monitor mood changes, coordinate mood stabilizing treatment or addiction care, and respond if symptoms worsen rather than improve.

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