Four placebo-controlled trials found that extended antibiotics give no lasting benefit for chronic Lyme disease (PTLDS). The evidence favors symptom-focused care, a search for other causes and carefully chosen off-label options such as low-dose naltrexone.
Multiple sclerosis is a chronic autoimmune disease that attacks myelin in the brain and spinal cord, affecting nearly 2.8 million people worldwide, with care ranging from disease-modifying therapies to emerging regenerative options.
A comprehensive, system-by-system guide to MCAS symptoms — skin, GI, cardiovascular, neurological, and more — with a symptom checklist, common triggers, and how to differentiate MCAS from allergies and anxiety.
MS symptoms vary wildly between patients. Here’s how the disease presents, what early signs look like, and how symptom patterns predict disease course.
The most common early signs of MS are numbness or tingling, blurred or painful vision in one eye, unusual fatigue, limb weakness and balance problems. Here is what each looks like, what mimics MS, and when to push for an MRI.
Guttate psoriasis is a sudden rash of small, drop-shaped scaly spots that usually appears 2 to 3 weeks after strep throat. Many flares clear within 3 to 4 months with phototherapy or topical steroids, while about a third become chronic plaque psoriasis.
Low dose naltrexone (LDN) at 1.5-4.5mg is used off-label for autoimmune conditions, chronic pain, and neuroinflammation. This evidence-based guide covers how LDN works, conditions it treats, dosing protocols, side effects, and how to get a prescription.
Mast cell activation syndrome (MCAS) is an immune disorder in which mast cells release histamine and other mediators too easily, causing episodic symptoms in two or more organ systems. This guide covers symptoms, diagnostic criteria, triggers, layered treatment and the MCAS, POTS and EDS triad.
At a Glance Up to 50% of “idiopathic” small fiber neuropathy cases may be autoimmune in origin – meaning the immune system is attacking the nerves. Sjögren’s syndrome is the leading autoimmune cause, followed by celiac disease, lupus, sarcoidosis, and Hashimoto’s thyroiditis. Specialized antibody testing – TS-HDS and FGFR3 antibodies – can identify autoimmune SFN,…
Dermatologists advise keeping a fragrance-free ceramide moisturizer, such as CeraVe, in daily use during dupilumab therapy, as the pivotal trials did. Here is the full eczema treatment ladder from emollients to biologics, with a routine for children.
The most common MCAS triggers are high-histamine foods, alcohol, heat, fragrances, mold, stress, poor sleep, hormonal shifts, infections and medications such as NSAIDs and opioids. Triggers differ by person and add up, so a tracked journal reveals yours.
