A comprehensive, system-by-system guide to MCAS symptoms — skin, GI, cardiovascular, neurological, and more — with a symptom checklist, common triggers, and how to differentiate MCAS from allergies and anxiety.
Mast cell activation syndrome (MCAS) is an immune disorder in which mast cells release histamine and other mediators too easily, causing episodic symptoms in two or more organ systems. This guide covers symptoms, diagnostic criteria, triggers, layered treatment and the MCAS, POTS and EDS triad.
The most common MCAS triggers are high-histamine foods, alcohol, heat, fragrances, mold, stress, poor sleep, hormonal shifts, infections and medications such as NSAIDs and opioids. Triggers differ by person and add up, so a tracked journal reveals yours.
