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Evolve Longevity Center
MD on staff OIG Cleared

Evolve Longevity Center

4000 Barranca Pkwy #250, Irvine, CA 92604, United States, 92604 Irvine, CA
5.00

About this clinic

Evolve Longevity Center, a hormone optimization clinic in Irvine, specializes in hormone replacement therapy and individualized hormone therapy for women navigating midlife and age-related decline. The practice takes a functional-medicine approach to hormone assessment, using comprehensive lab work to guide treatment selection and ongoing adjustments. Protocols are tailored to each patient's symptoms, lab results, and health goals rather than applied uniformly. The clinic focuses on restoring hormonal balance to support energy, mood, bone health, and overall physiologic function. Follow-up monitoring ensures treatments remain aligned with each patient's evolving needs and responses.

Treatments offered

Contact information

4000 Barranca Pkwy #250, Irvine, CA 92604, United States
92604 Irvine, CA

Office hours

Monday – Friday
9am – 5pm
Saturday – Sunday
Closed

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Patient reviews

5.00

Based on 19 Google reviews

5 ★
4 ★
3 ★
2 ★
1 ★

Dr. Van at Evolve Longevity Center has seriously changed my life. When I first met her, I had no energy, was on Adderall and anti-depressants, was unable to lose weight, my body was inflamed, I had brain fog, and felt sick all the time. Dr. Van, being the transformational healer she truly is, changed everything for me. I am 41 years old and thought I would never feel like my true self again. After only four months, I feel like a new woman. Through HRT, IV treatment, and individualized supplements, I have been able to stop taking Adderall, lower my anti-depressant medications, lose weight, and, most importantly, have brain clarity and energy again! Through extremely thorough testing, Dr. Van was able to bring my body back to its optimal potential. Dr. Van truly changed my life. I can't thank her enough for taking the time to help me heal my body from the inside out. I would highly recommend any woman to see her. She will truly transform your life!

Krystal Thorburn · March 6th, 2026

I’ve lived with fibromyalgia since I was 25, and now at 45 I can honestly say I’ve never experienced the level of care, attention, and the best results with Dr. Van at Evolve Longevity Center of Irvine.For years I felt like I was just “existing” — losing muscle mass, exhausted, no sex drive, my skin aging rapidly, and no real luster for life. Since working with her, everything has changed. She spent a full hour going through my labs with me, explaining things no other doctor ever took the time to break down. She even adjusted her schedule so we could stay consistent with my IV therapy plan. The results have been incredible. I went from losing muscle at an alarming rate to being in the gym six days a week, completing full workouts, and actually seeing muscle gain again. My energy, mood, skin, and overall sense of well‑being have all improved dramatically. I finally feel like myself again — and honestly, better than I have in decades. I’m grateful for her expertise, her compassion, and her commitment to helping me heal. Truly a great experience, and I’m excited for what’s ahead.

Kortney Franco · March 2nd, 2026

Dr Van has changed my health/life in ways I didn't think were possible. I have a history of autoimmune/other serious medical issues and felt like I had tried everything to the point of wanting to just give up. So while I was interested in more natural ways of healing and optimizing my health, I was very skeptical about trying something new. However, what differentiated Dr Van for me in the beginning was her experience in both western medicine combined with functional medicine. I've been working with Dr Van for ~6 months and she continues to surpass my expectations - for the first time in a long time, I'm sleeping better, feeling more energized, having more mental clarity and losing weight the safe way. I've never met a doctor who is so attentive to my unique needs, excellent at explaining complex things in simple terms to understand my options, and always available via phone/text to answer questions. I liked how her program has been deliberately build on phases or building blocks that help maximize results along the way as each phase stabilizes. She started with extensive blood work to establish a baseline of my overall health instead of rushing/trying to sell me on the typical hormone/other therapies prematurely that likely would not have been successful w/o addressing the root of my baseline health needs first. Traditional bloodwork with my primary care doctor missed so many important imbalances in my hormones and my health. Dr Van identified some surprising food allergies and other health imbalances, which helped shape what we started working on improving through diet refinement, supplements and IVs. From there, we progressed into hormone/other therapies. My journey is still going, but I am truly grateful for the noticeable improvements and new habits in my day to day life so far.

Shannon Knauss · October 18th, 2025

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