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Read the Ketamine Therapy guide for the educational context behind this treatment category.
Brooklyn, NY
Ketamine Therapy clinics in Brooklyn
Choosing ketamine therapy in Brooklyn for treatment-resistant depression starts with comparing psychiatric assessment, medical supervision and follow-up. A prominent search result does not establish which provider fits your history. Use the listings to find a practice that reviews previous depression treatments, explains its approach and coordinates with your existing mental health clinician.
Brooklyn options include medical offices around Court Street in Brooklyn Heights, near Downtown Brooklyn, and along Broadway in South Williamsburg, with psychiatric practices also offering ketamine services in Park Slope. These are different journeys from southern or eastern Brooklyn, so confirm the treatment address rather than relying on a general NYC service area. Court Street and Borough Hall serve the Brooklyn Heights area, while Marcy Avenue serves South Williamsburg. Plan the return trip with the practice before booking, including an escort if required; proximity to a subway station does not mean traveling alone after treatment is appropriate.
Local services can include monitored IV infusions in medical offices or ketamine paired with psychotherapy. Ask whether the service is IV ketamine, nasal esketamine or another formulation, and who administers it. An initial assessment should cover diagnosis, previous treatment, medications, substance use and medical risks, followed by a plan to track symptoms and review whether continuing makes sense. IV ketamine for depression is off-label, meaning it is not FDA approved for that use; nasal esketamine has specific approved depression indications and supervised administration requirements.
Before committing, ask about the prescriber's credentials, who stays on site, the medication's source and emergency procedures. Request written risks and side effects, an explanation of what happens if symptoms do not improve, and an itemized quote showing assessments, medication, monitoring, psychotherapy and follow-up charges. IV treatment is commonly cash pay, and evidence about sustained benefit and long-term repeated use remains limited.
Regenerated.com is free for patients, and organic listing order cannot be bought. Featured spaces are labeled and capped, while Verified means credential checks, not spending; inclusion is not an endorsement.
The national ketamine therapy hub explains the mechanism and broader evidence. For help interpreting local listings, read How to read a Regenerated city hub and Featured vs Verified vs organic.
3 Clinics
Regulatory context
A note on New York's ketamine therapy rules.
Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.
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S 3520 / Psilocybin Assisted Therapy (2023)
Proposed a state psilocybin therapy framework; pending. -
A 114 / Psychedelic Decriminalization (2023)
Proposed decriminalization of possession and use of psilocybin, MDMA, DMT, mescaline, and ibogaine; pending. -
New York Public Health Law Article 33
Mirrors federal scheduling and governs controlled substance prescribing; requires NY-specific practitioner registration.
New York enforces federal and state scheduling. The New York State Bureau of Narcotic Enforcement (BNE) requires practitioners to obtain a New York State Controlled Substance License in addition to federal DEA. The Office of Professional Medical Conduct oversees prescriber discipline. DEA enforcement on ketamine clinics focuses on diversion and Ryan Haight Act telehealth compliance. New York PMP (I-STOP) requires electronic prescribing for controlled substances.
Ketamine Therapy in Brooklyn, answered.
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