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Clinics in Portland, Oregon

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

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Portland, OR

Stem Cell Therapy clinics in Portland

Portland supports a regenerative medicine market shaped by both private clinics and regional academic medicine. Local referral networks run through Oregon Health & Science University (OHSU) and Legacy Health, and stem cell practice in the area spans the Pearl District, Northwest, and Lake Oswego. Patient demand splits across three buckets: orthopedic injections for active adults and aging athletes, neurological and autoimmune protocols marketed to longevity-focused patients, and IV-based allogeneic products offered by private wellness clinics. The FDA classifies most stem cell injections for orthopedic, neurological, or longevity use as investigational biologics under 21 CFR Part 1271, meaning they require either a Biologics License or an active Investigational New Drug authorization. Autologous bone marrow and adipose products may qualify as Section 361 when minimally manipulated and used for homologous function. Oregon regulates physician practice through the Oregon Medical Board. There is no Oregon-specific stem cell statute, so federal 21 CFR Part 1271 rules apply. The state's bioethics climate has drawn academic trial activity at OHSU. The 10 Portland clinics listed below have been reviewed against our vetting criteria, including federal NPI lookup, OIG exclusion screening, and Oregon Medical Board licensure checks.

8 Clinics

MD on staff

The Natural Path

Portland, OR

The Natural Path, a regenerative medicine clinic in Portland, specializes in hormone optimization and cell-based therapies for sexual wellness, musculoskeletal conditions, and age-related decline. Th…

  • PRP Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • Arthritis Treatment
  • Peptide Therapy

Orsleeptmj

Portland, OR

Orsleeptmj, a regenerative musculoskeletal and pain clinic in Portland, Oregon, specializes in stem-cell therapy for temporomandibular joint (TMJ) dysfunction and jaw pain. The practice offers custom…

  • Sleep Apnea Treatment
  • TMJ Treatment
  • Stem Cell Therapy

Upgrade Medical

Portland, OR

Upgrade Medical, a regenerative medicine clinic in Portland, offers cell-based therapies including stem-cell and exosome approaches alongside platelet-rich plasma and prolotherapy for musculoskeletal…

  • PRP Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Arthritis Treatment
  • Cryotherapy
MD on staff

NW Regen

Portland, OR

NW Regen, a regenerative medicine clinic in Portland, specializes in orthobiologic and cell-based therapies for musculoskeletal conditions and men's health. The practice offers platelet-rich plasma i…

  • PRP Therapy
  • Arthritis Treatment
  • Migraine Treatment
  • Psychedelic Therapy
  • Erectile Dysfunction (ED) Treatment

Rise2Health

Portland, OR

Rise2Health, an Integrative Medicine Clinic in Portland, Oregon, offers hormone replacement therapy alongside regenerative injection therapy for patients pursuing functional restoration and longevity…

  • PRP Therapy
  • Ozone Therapy
  • Arthritis Treatment
  • Peptide Therapy
  • Hormone Replacement Therapy (HRT)
MD on staff

Open Wellness PDX

Portland, OR

Open Wellness PDX, a regenerative medicine clinic in Portland, specializes in orthobiologics and tissue-support therapies for musculoskeletal conditions and sports injuries. The practice offers plate…

  • PRP Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • Laser Therapy (LLLT)
  • Psoriasis Treatment
MD on staff

Sports Health Northwest

Portland, OR

Sports Health Northwest, a regenerative medicine clinic in Portland, specializes in orthobiologic and cell-based therapies for musculoskeletal and sports-related conditions. The practice offers plate…

  • PRP Therapy
  • IV Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
  • Erectile Dysfunction (ED) Treatment
MD on staff

Open Wellness PDX

Portland, OR

David Chang, ND, LAc, a naturopathic and regenerative-medicine clinic in Portland, provides individualized treatment planning for patients seeking supportive care outside conventional-medicine pathwa…

  • PRP Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • Acne Treatment
  • Psoriasis Treatment
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Regulatory context

A note on Oregon's stem cell therapy rules.

Oregon cellular therapy is governed by 21 CFR Part 1271. Section 361 covers minimally manipulated HCT/Ps used for homologous use without premarket approval. Section 351 covers products that are more than minimally manipulated, used non-homologously, or combined with another article, and these require an IND for clinical use or a BLA for marketing. Most stem cell, stromal vascular fraction, and exosome therapies marketed in Oregon for orthopedic, neurologic, and longevity indications are Section 351 biologics that lack FDA approval. Oregon licenses naturopathic doctors with one of the broadest scopes in the country, which can affect who legally administers some therapies.

  • Oregon Medical Practice Act, ORS Chapter 677
    Establishes physician licensure and discipline through the Oregon Medical Board.
  • Oregon Naturopathic Physicians Act, ORS Chapter 685
    Provides licensed naturopathic physicians with prescriptive and injection authority broader than most states; specific cellular biologic injections may still fall outside scope and remain subject to FDA constraints.
  • Oregon Pharmacy Practice Act, ORS Chapter 689
    Regulates compounding pharmacies aligned with federal 503A and 503B standards.

The FDA has corresponded with Oregon providers offering cellular therapies. The Oregon Medical Board has disciplined physicians for unprofessional conduct including misleading regenerative medicine advertising. The Oregon Board of Naturopathic Medicine has disciplinary authority over NDs operating outside scope. The Oregon Attorney General has used the Oregon Unlawful Trade Practices Act to pursue providers making unsupported clinical claims. Federal warning letters apply nationally.

Stem Cell Therapy in Portland, answered.

Most stem cell therapies at private Portland clinics are not FDA-approved. The FDA has approved certain hematopoietic stem cell products for blood and immune disorders, but stem cell injections for orthopedic, neurological, or longevity use are generally investigational. They require a Biologics License or an active Investigational New Drug authorization, or they must qualify as Section 361 minimally manipulated and homologous-use products under 21 CFR Part 1271. Oregon regulates physician practice through the Oregon Medical Board.

In the Portland metro, single-joint autologous bone marrow or adipose injections typically run $4,000 to $12,000 per session. Systemic IV protocols using allogeneic umbilical cord or Wharton's jelly products range $8,000 to $20,000, and full multi-session protocols can reach $15,000 to $40,000. Exosome add-ons range $3,500 to $7,500. Insurance rarely covers these treatments because the FDA classifies most protocols as investigational.

Autologous stem cells come from your own body, usually harvested from bone marrow aspirate or adipose tissue and reinjected the same day. When minimally manipulated and used for homologous function, they often fall under FDA Section 361, which does not require pre-market approval. Allogeneic stem cells come from a donor source, most commonly umbilical cord blood or Wharton's jelly, and are generally classified as Section 351 biologics that require an active Investigational New Drug authorization. Portland clinic offerings span both categories, so ask which classification applies before treatment.

Yes. Research programs at Oregon Health & Science University (OHSU) and Legacy Health periodically run FDA-authorized stem cell trials across orthopedics, neurology, cardiology, and oncology. Search clinicaltrials.gov and filter by Portland or the broader metro to see active recruiting studies. Trial participation is typically low-cost or free compared to commercial protocols and includes structured follow-up with imaging and lab monitoring.

Verify physician licensure through the Oregon Medical Board and confirm the clinic's NPI number through the NPPES registry. Check the FDA warning letter database for the clinic name and the HHS Office of Inspector General exclusion list. Ask whether the treatment is Section 361 or Section 351, whether the clinic operates under an Investigational New Drug authorization for allogeneic or expanded products, and whether adverse events are tracked. Ask specifically about compliance with federal 21 CFR 1271.

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