At a Glance You cannot absorb NAD+ directly from oral supplements; the molecule is too large to cross the intestinal lining intact and must be synthesized inside cells from precursors. Oral NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide) do raise blood NAD+ levels by 40-90%, as shown in human trials, but the clinical significance of…
TMS uses magnetic pulses to stimulate underactive brain circuits in people with treatment-resistant depression. Learn about response rates, what sessions feel like, the accelerated SAINT protocol, and how TMS compares to medication and ECT.
There’s no cure for Ehlers-Danlos syndrome, but the right combination of physical therapy, pain management, and lifestyle adjustments can dramatically improve function and quality of life. Here’s what works, what doesn’t, and what’s emerging.
Exercise is one of the most effective treatments for osteoarthritis, yet most people with OA don’t do enough of it. This guide covers the best types of exercise by joint, what to avoid, and how to get started even when your joints hurt.
At a Glance Fibromyalgia flares are characterized by intensified widespread pain, fatigue, cognitive symptoms, and sleep disruption beyond the patient’s usual baseline level. The most common identifiable triggers are psychological stress, sleep disruption, overexertion (physical or cognitive), weather changes, and infections. Central sensitization worsens during flares: the pain amplification system becomes more reactive, meaning even…
At a Glance Extracorporeal shockwave therapy (ESWT) is best supported for calcific tendinitis of the shoulder, with strong evidence from multiple RCTs and systematic reviews. Rotator cuff tendinopathy and frozen shoulder (adhesive capsulitis) also have meaningful evidence, though less definitive than for calcific tendinitis. Focused shockwave penetrates deeper and is preferable for calcifications; radial shockwave…
At a Glance True IgE-mediated food allergies trigger eczema in a minority of patients, most commonly in children under 5, while non-allergic food sensitivities are far more common in adults. Dairy, eggs, soy, wheat, and tree nuts are the most frequently identified dietary triggers, but no single food causes flares in all patients. A 4-6…
Selank is a synthetic peptide derived from the immune-modulating molecule tuftsin. Developed in Russia, it has demonstrated anxiolytic and nootropic effects through GABA modulation and BDNF upregulation. Here is what the research shows about dosing, delivery, and clinical outcomes.
At a Glance What it is: Pressurized-chamber oxygen therapy (1.5-2.0 ATA) applied over 40-60 sessions to address persistent Long COVID symptoms. Key evidence: A 2022 Israeli randomized controlled trial demonstrated significant cognitive and fatigue improvements in Long COVID patients after HBOT. Best for: Brain fog, chronic fatigue, exercise intolerance, and neurological symptoms that have persisted…
Osteoarthritis at a Glance What Osteoarthritis Actually Is (It Is Not Just Wear and Tear) For decades, doctors described osteoarthritis as a “wear and tear” disease. That framing is outdated, incomplete, and frankly misleading. Yes, mechanical stress plays a role. But OA is a whole-joint disease with active biological processes driving its progression. Here is…
At a Glance Neurofeedback for ADHD has been rated as a Level 1 “Best Support” (Established) intervention by the American Academy of Pediatrics, the highest evidence rating. The most studied protocols for ADHD are SMR (sensorimotor rhythm) training and theta/beta ratio training. A typical treatment course involves 30 to 40 sessions, usually 2 to 3…
Pustular psoriasis is a rare and potentially serious form of psoriasis that produces pus-filled blisters on the skin. Learn about the different types, what triggers flares, and the newest treatment options.
