Stem cell therapy for knees injects concentrated cells, usually BMAC or SVF, into an arthritic knee to ease pain. Many patients improve, but the largest trial (Nature Medicine, 2023) found it no better than a steroid shot at 12 months.
MCAS, POTS, and EDS often occur together because all three trace back to shared connective tissue problems that destabilize mast cells and blood vessels, with over half of hEDS patients also meeting MCAS criteria.
A clinical guide to intra-articular ozone injections for knee OA and other joint conditions: how it works, RCT evidence versus hyaluronic acid and corticosteroids, prolozone, treatment protocols, and cost.
Adrenal fatigue is not a recognized diagnosis, so insomnia blamed on it is treated like any chronic insomnia: CBT-I first, plus testing for sleep apnea, thyroid disease, iron deficiency and depression.
Mast cell activation syndrome causes symptoms in two or more organ systems at once, from flushing and hives to brain fog and anaphylaxis. Here is how to recognize the pattern, get diagnosed, and find treatment options.
Rifaximin is the gold standard antibiotic for SIBO, but treatment protocols differ based on whether you have hydrogen, methane, or hydrogen sulfide overgrowth. Here’s how each antibiotic works, what the success rates look like, and when retreatment is needed.
NAD+ therapy eases brain fog by restoring mitochondrial energy production, calming neuroinflammation, and supporting DNA repair, with IV infusions acting fastest and oral NMN or NR supporting maintenance.
Rheumatoid arthritis is an autoimmune disease of the joint lining, while osteoarthritis is a degenerative disease of the whole joint. Compare symptoms, diagnosis, DMARDs, and the evidence for PRP, stem cells, prolotherapy and peptides.
A practical guide to eating with mast cell activation syndrome, covering high-histamine foods, histamine liberators, DAO inhibitors, safe food lists, and strategies for meal planning and reintroduction.
At a Glance Prolotherapy involves injecting a sugar (dextrose) solution into damaged ligaments and tendons to trigger a controlled healing response. Evidence is strongest for sacroiliac joint pain and chronic low back pain from ligament laxity, with several RCTs showing meaningful improvement. A typical course runs 4 to 6 sessions spaced 3 to 6 weeks…
Fibromyalgia is linked to measurable changes in the gut microbiome, and a 2025 study showed gut bacteria from patients can cause pain in mice. SIBO testing, diet change and probiotics are reasonable add-ons to standard care, though the trials are still small.
