At a Glance Low dose naltrexone (LDN) uses 1.5 to 4.5 mg nightly, far below the 50 mg dose used for addiction treatment, to modulate the immune system rather than block opioid receptors. Jill Smith’s 2011 pilot RCT at Penn State showed 88% clinical response and 33% remission in pediatric Crohn’s using 0.1 mg/kg LDN….
The SIBO breath test is the most common non-invasive method for diagnosing small intestinal bacterial overgrowth. Learn how lactulose and glucose tests work, what positive thresholds mean, how to prepare, and when at-home testing makes sense.
Celiac disease is an autoimmune disorder in which gluten makes the immune system damage the small intestine. It affects about 1 in 100 people, and the only established treatment is a strict, lifelong gluten-free diet.
Rifaximin is the gold standard antibiotic for SIBO, but treatment protocols differ based on whether you have hydrogen, methane, or hydrogen sulfide overgrowth. Here’s how each antibiotic works, what the success rates look like, and when retreatment is needed.
Fibromyalgia is linked to measurable changes in the gut microbiome, and a 2025 study showed gut bacteria from patients can cause pain in mice. SIBO testing, diet change and probiotics are reasonable add-ons to standard care, though the trials are still small.
Migraine and gut health are linked through the gut-brain axis: over 90% of serotonin is made in the gut, and migraine patients are 2 to 3 times more likely to have GI conditions like IBS.
In Reno, Nevada, fecal microbiota transplant (FMT) is a specialist treatment for recurrent C. diff, with two FDA approved products, Rebyota (2022) and Vowst (2023). For IBS, Crohn's disease and ulcerative colitis it remains investigational and is best accessed through a clinical trial.
Oral BPC-157 healed ulcers, colitis and fistulas in rat studies because it survives stomach acid, but no human trial has tested it for any gut condition. Here is the animal evidence, the doses practitioners use, and where FDA stands.
Colon hydrotherapy, or colonic irrigation, runs warm filtered water into the colon through a rectal tube over 45 to 60 minutes. Its best supported use is bowel prep before colonoscopy; constipation relief is promising, and detox claims are not supported.
At a Glance IBS is a diagnosis of exclusion based on symptom patterns. SIBO is a specific condition with measurable bacterial overgrowth in the small intestine. Up to 78% of IBS patients may actually have SIBO as the underlying cause of their symptoms. Testing is the key differentiator. Lactulose or glucose breath testing can identify…
Diet plays a significant role in managing Crohn’s disease, influencing inflammation, flares, and nutritional status. Here are the dietary approaches with the strongest evidence, plus practical guidance on what to eat during flares and remission.