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11 Best Ozone Therapy Clinics in San Francisco, California

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

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San Francisco, CA

Ozone Therapy clinics in San Francisco

Ozone Therapy in San Francisco, CA

intro

San Francisco, California has a visible integrative and functional medicine scene, and clinics in the area advertise ozone therapy as part of their services. Ozone is a three-oxygen molecule that practitioners deliver through several delivery methods, including major autohemotherapy (MAH), minor autohemotherapy (MinorAH), prolozone joint injections, rectal or vaginal insufflation, ozonated saline, and higher-dose protocols such as 10-pass ozone. The proposed mechanism is oxidative hormesis, a brief and controlled oxidative challenge that is theorised to upregulate endogenous antioxidant defences, modulate immune signalling pathways, and improve tissue oxygen utilisation at the mitochondrial level. It is critical to be clear with patients up front: ozone therapy is NOT FDA-approved for any medical use. The FDA issued a formal declaration in 1976 stating that ozone is a toxic gas with no known useful medical application, and that position has not been revised in the decades since. Clinics listed here offer ozone under physician clinical judgement, not under an approved indication, so patients should evaluate evidence quality, informed consent language, and provider credentials carefully before booking a session or committing to a package.

11 Clinics

MD on staff

Anatara Medicine

San Francisco, CA

Anatara Medicine, a functional and integrative medicine clinic in San Francisco, offers a range of supportive therapies including IV therapy, ozone therapy, and photobiomodulation alongside acupunctu…

  • Ozone Therapy
  • IV Therapy
  • Laser Therapy (LLLT)
  • Chelation Therapy
  • Lyme Disease Treatment
MD on staff

My Doctor Medical Group

San Francisco, CA

My Doctor Medical Group, a physician-owned concierge practice in San Francisco since 2008, specializes in ozone therapy, hyperbaric oxygen therapy, and intravenous nutrient infusions including NAD IV…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • Ozone Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Hormone Replacement Therapy (HRT)
MD on staff

Azzolino Chiropractic Neurology & Integrative Wellness

San Francisco, CA

Azzolino Chiropractic Neurology & Integrative Wellness, a functional and integrative medicine clinic in San Francisco, combines chiropractic care with functional neurology, rehabilitation, and naturo…

  • Ozone Therapy
  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy

John VanCamp, DDS

San Francisco, CA

John VanCamp, DDS, a regenerative dentistry practice in San Francisco, specializes in ozone therapy and laser treatment as part of a biological-dentistry approach. The practice emphasizes biocompatib…

  • Ozone Therapy
  • Laser Therapy (LLLT)

Integrative Dentistry

San Francisco, CA

Integrative Dentistry, a biological dentistry practice in San Francisco, offers ozone-supported procedures alongside conventional restorative and cosmetic dental care. The clinic focuses on minimally…

  • Ozone Therapy

Terapia Celular del Perú

San Francisco, CA

Terapia Celular del Perú, a regenerative medicine clinic in San Francisco, offers stem-cell therapy, platelet-rich plasma injections, and ozone therapy for tissue repair and age-related decline. The …

  • PRP Therapy
  • Ozone Therapy
  • IV Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment

TLC Medicine

San Francisco, CA

TLC Medicine, a functional and integrative medicine clinic in San Francisco, offers acupuncture, ozone therapy, and integrative-medicine workups for patients with chronic pain and autoimmune conditio…

  • Ozone Therapy
  • Multiple Sclerosis (MS) Treatment
  • Arthritis Treatment
  • Psoriasis Treatment

Healthwell Physical Therapy Group

San Francisco, CA

Healthwell Physical Therapy Group, a regenerative-medicine clinic in San Francisco, offers a comprehensive range of cell-based therapies, orthobiologics, and energy-based treatments. The clinic featu…

  • PRP Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
MD on staff

Biotherapy Clinic

San Francisco, CA

Biotherapy Clinic, in San Francisco, offers colon hydrotherapy and ozone-based therapies alongside acupuncture and IV protocols for metabolic and immune support. The clinic specializes in digestive o…

  • Colon Hydrotherapy
  • Ozone Therapy
  • IV Therapy
  • Arthritis Treatment
  • Chelation Therapy
MD on staff

Clarus Health

San Francisco, CA

Clarus Health, a ketamine and NAD clinic in San Francisco, specializes in ketamine infusion and esketamine therapy alongside NAD IV therapy for treatment-resistant depression, anxiety, chronic pain, …

  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Ketamine Therapy
  • Migraine Treatment
MD on staff

Pacific Naturopathic

San Francisco, CA

Pacific Naturopathic, a functional and integrative medicine clinic in Los Altos, offers ozone therapy and infrared sauna alongside acupuncture, botanical medicine, and IV therapy. The practice provid…

  • Colon Hydrotherapy
  • Ozone Therapy
  • IV Therapy
  • IV Hydration
  • Hormone Replacement Therapy (HRT)
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Regulatory context

A note on California's ozone therapy rules.

The "other" category is a catchall for regenerative wellness modalities with inconsistent federal oversight. Red light therapy devices (photobiomodulation) have narrow FDA 510(k) clearances for acne, muscle pain, and wound healing, not systemic regeneration. Whole-body cryotherapy is NOT FDA-approved for any medical indication and received an FDA safety communication in July 2016 warning of asphyxiation, frostbite, and burn risks. Ozone therapy is NOT FDA-approved for any medical use and the FDA has stated ozone is a toxic gas with no known useful medical application. Condition-specific regenerative offerings (hair restoration with minoxidil or finasteride, ED care beyond PDE5 inhibitors and shockwave) have varying approval depending on route and drug source.

  • California Medical Practice Act (Bus. & Prof. Code §§ 2000-2529)
    Defines medical practice and corporate practice of medicine prohibitions strictly enforced against lay-owned medical spas.
  • California Business & Professions Code §§ 2051-2052
    Prohibits unlicensed practice of medicine and aiding and abetting by non-physician owners.
  • Board of Registered Nursing Standardized Procedures (CCR Title 16 § 1474)
    Requires physician-developed standardized procedures for RNs performing cosmetic and wellness injections or laser work.

California is among the strictest enforcement states. The Medical Board of California has issued public advisories and taken disciplinary action against medical spas for corporate practice of medicine violations, unsupervised RN injections, and false advertising of unapproved therapies. Ozone therapy is heavily scrutinized and clinics making cancer or infection treatment claims risk board discipline and Attorney General consumer protection action. The California Department of Public Health and local health departments also investigate facility and infection control issues at wellness clinics.

Ozone Therapy in San Francisco, answered.

No. Ozone therapy is NOT FDA-approved for any medical use. The FDA issued a 1976 declaration stating ozone is a toxic gas with no known useful medical application, and that position has not changed. Clinics that offer ozone do so under physician clinical judgement, not under an approved indication. Many marketing claims for ozone are unsupported by high-quality clinical evidence, so any informed decision about booking a session should start with that clear disclosure.

Pricing in San Francisco typically runs $200 to $400 per session for standard major autohemotherapy (MAH), with prolozone joint injections, insufflation, and MinorAH often priced similarly or slightly lower. Higher-dose 10-pass ozone is considerably more expensive, usually $600 to $900 per session, with packages of six to ten sessions priced substantially higher. Package pricing can lower the per-session rate but raises total spend. Remember that ozone is NOT FDA-approved, is not covered by insurance, and out-of-pocket cost is the norm.

Integrative practitioners commonly claim benefits for immune support, chronic infections such as Lyme disease and herpes, systemic inflammation, chronic fatigue, autoimmune conditions, and musculoskeletal pain using prolozone for joints and discs. The quality of clinical evidence supporting these claims is low, studies are often small or uncontrolled, and ozone therapy is NOT FDA-approved for any of these indications. Treat strong claims with caution.

In California, ozone therapy is most commonly delivered by MDs and DOs practising integrative or functional medicine, because naturopathic scope is either limited or unlicensed. Chiropractors generally cannot administer intravenous ozone, and scope varies by state medical and naturopathic board positions. Regardless of license type, verify active state licensure before any appointment, and remember that ozone therapy is NOT FDA-approved and is offered under physician clinical judgement rather than any approved indication.

Verify that the lead clinician holds an active state license, ask for written informed consent that clearly states ozone is NOT FDA-approved, and look for realistic evidence framing rather than cure claims. Avoid clinics that promise to cure cancer, autoimmune disease, or chronic infection. Membership in groups such as the AAOT is a peer-community signal, not an FDA credential, and should never substitute for verifying licensure and reading consent forms.

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