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Read the Ketamine Therapy guide for the educational context behind this treatment category.
Denver, CO
Ketamine Therapy clinics in Denver
A ketamine treatment center in Denver can be a psychiatric office, an infusion suite, or a wellness clinic, and the first thing to confirm is the delivery method: an intramuscular injection goes into a muscle, while an intravenous infusion delivers medication through a vein. Denver ketamine therapy options include offices around Cherry Creek near Colorado Boulevard and offerings west in Lakewood, where muscle injections are available. Centers may advertise service across the metro, including Aurora to the east and Boulder northwest along US-36, so confirm the treatment address. Arrange an adult escort home and follow written instructions about when driving can resume.
Expect injection treatment in a medical or psychiatric office, with licensed medical staff administering medication and monitoring recovery. People may seek a ketamine treatment center after standard care for depression, anxiety, PTSD, or chronic pain has not helped enough, but these uses have different evidence, and a Denver clinic should assess your specific diagnosis. An initial consultation should review your diagnosis, previous treatments, medications, blood pressure, and substance use history. Ask who prescribes, who monitors you throughout treatment, and what training the team has in managing breathing problems or severe distress. Confirm whether psychotherapy is included or arranged separately.
Before booking, request the medication's formulation and source, plus written information about side effects, risks, and discharge instructions. Clinicians can prescribe ketamine off-label for depression or other mental health conditions, meaning the FDA has not approved those uses. Ketamine is a legal prescription medication when licensed clinicians prescribe and supervise it, and ketamine clinics are separate from Colorado's licensed psilocybin healing centers. Ask how follow-up tracks symptoms and daily functioning, who handles concerns between visits, and when treatment would change if it does not help. A written quote should distinguish assessment, medication, monitoring, psychotherapy, and follow-up, with additional charges identified. Evidence about sustained benefit remains limited, and this is usually cash pay.
Regenerated.com does not sell organic listing order or paid ranking within it. Featured placements are labeled and limited in number, while Verified indicates credential checks rather than spending. The directory is free for patients, and inclusion does not endorse a provider or treatment.
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30 Clinics,
Axis Integrated Mental Health
- Transcranial Magnetic Stimulation (TMS)
- Ketamine Therapy
Heartmind Medicine
- Neurofeedback Therapy
- Ketamine Therapy
- Psychedelic Therapy
Infusion IV Lounge
- NAD IV Therapy
- Vitamin IV Therapy
- IV Therapy
- IV Hydration
- Ketamine Therapy
Shadid Integrative Psychiatry - Nicole Shadid M.D.
- Biofeedback Therapy
- Neurofeedback Therapy
- Ketamine Therapy
- Psychedelic Therapy
- Hormone Replacement Therapy (HRT)
Dana McDowell New Beginnings Psychotherapy Ketamine-Assisted Psychotherapy
- Ketamine Therapy
Regulatory context
A note on Colorado's ketamine therapy rules.
Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.
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Colorado Proposition 122 / Natural Medicine Health Act (2022)
Decriminalized personal use of psilocybin, psilocyn, DMT, ibogaine, and mescaline (non-peyote) for adults 21+; authorized state-licensed Healing Centers for psilocybin-assisted therapy, with MDMA access permitted by state rule after June 2026. -
SB 23-290 Natural Medicine Regulation and Legalization
Implementing legislation establishing the Natural Medicine Division within DORA and the licensure framework for facilitators, healing centers, cultivators, and product manufacturers.
Colorado Healing Centers began licensing and operating in late 2024 and early 2025. The Colorado Department of Regulatory Agencies (DORA) Natural Medicine Division oversees facilitator licensure, healing center operations, testing, and track-and-trace. Federal law still classifies psilocybin as Schedule I, so DEA enforcement risk remains theoretical. The Colorado Medical Board regulates ketamine prescribing. Ryan Haight Act applies to telehealth ketamine.
Ketamine Therapy in Denver, answered.
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Ketamine Therapy in ColoradoNationwide
Ketamine Therapy clinics across the US