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9 Best Ozone Therapy Clinics in Denver, Colorado

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Denver, CO

Ozone Therapy clinics in Denver

Ozone Therapy in Denver, CO

intro

Denver, Colorado has a visible integrative and functional medicine scene, and clinics in the area advertise ozone therapy as part of their services. Ozone is a three-oxygen molecule that practitioners deliver through several delivery methods, including major autohemotherapy (MAH), minor autohemotherapy (MinorAH), prolozone joint injections, rectal or vaginal insufflation, ozonated saline, and higher-dose protocols such as 10-pass ozone. The proposed mechanism is oxidative hormesis, a brief and controlled oxidative challenge that is theorised to upregulate endogenous antioxidant defences, modulate immune signalling pathways, and improve tissue oxygen utilisation at the mitochondrial level. It is critical to be clear with patients up front: ozone therapy is NOT FDA-approved for any medical use. The FDA issued a formal declaration in 1976 stating that ozone is a toxic gas with no known useful medical application, and that position has not been revised in the decades since. In Colorado, licensed NDs have a broader scope and some ozone providers are NDs working with MDs or DOs. Clinics listed here offer ozone under physician clinical judgement, not under an approved indication, so patients should evaluate evidence quality, informed consent language, and provider credentials carefully before booking a session or committing to a package.

9 Clinics

Grossman Wellness Center

Grossman Wellness Center

Denver, CO

Grossman Wellness Center, a longevity and anti-aging practice in Denver, specializes in hormone optimization, peptide therapy, and regenerative-medicine protocols designed to support healthy aging an…

  • PRP Therapy
  • Ozone Therapy
  • IV Therapy
  • Arthritis Treatment
  • Peptide Therapy
Denver Osteopathic and Sports Medicine Center

Denver Osteopathic and Sports Medicine Center

Denver, CO

Denver Osteopathic and Sports Medicine Center, in Aurora, offers ozone therapy and peptide therapy alongside osteopathic care for musculoskeletal and sports-related conditions. The practice focuses o…

  • Ozone Therapy
  • Peptide Therapy
Medicine with Heart Functional Medicine Clinic
MD on staff

Medicine with Heart Functional Medicine Clinic

Denver, CO

Medicine with Heart Functional Medicine Clinic, located in Lakewood, Colorado, offers an integrative-medicine approach centered on identifying and treating root causes of chronic health conditions. T…

  • Ozone Therapy
  • IV Therapy
  • Lyme Disease Treatment
Recovery 1
MD on staff

Recovery 1

Denver, CO

Recovery 1, a longevity clinic in Glendale, offers regenerative and recovery modalities including platelet-rich plasma therapy, peptide therapy, and ozone therapy. The clinic features cryotherapy and…

  • PRP Therapy
  • Ozone Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
  • Cryotherapy
Back 2 Movement Sports Medicine
MD on staff

Back 2 Movement Sports Medicine

Denver, CO

Back 2 Movement Sports Medicine, a regenerative sports-medicine clinic in Wheat Ridge, Colorado, specializes in platelet-rich plasma therapy and shockwave therapy for musculoskeletal injuries and spo…

  • PRP Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • Arthritis Treatment
  • Erectile Dysfunction (ED) Treatment
Monarch Integrative Health

Monarch Integrative Health

Denver, CO

Monarch Integrative Health, a regenerative medicine clinic in Denver, specializes in functional medicine with an emphasis on individualized treatment planning. The clinic offers ozone therapy and pep…

  • Ozone Therapy
  • Lyme Disease Treatment
  • Peptide Therapy
  • Erectile Dysfunction (ED) Treatment
  • Hormone Replacement Therapy (HRT)
Grossman Wellness Center

Grossman Wellness Center

Denver, CO

Grossman Wellness Center, a longevity clinic in Glendale, specializes in functional-medicine workups and hormone-replacement therapy alongside regenerative modalities including NAD IV Therapy and Ozo…

  • Ozone Therapy
  • IV Therapy
  • Lyme Disease Treatment
  • Peptide Therapy
  • Hormone Replacement Therapy (HRT)
BioVital IV Infusion Clinic
MD on staff

BioVital IV Infusion Clinic

Denver, CO

BioVital IV Infusion Clinic, located in Denver, specializes in intravenous nutrient therapy and vitamin infusions alongside complementary supportive modalities. The clinic offers ozone therapy, red-l…

  • Vitamin IV Therapy
  • Colon Hydrotherapy
  • Ozone Therapy
  • IV Therapy
  • Arthritis Treatment
South Lakewood Dental
MD on staff

South Lakewood Dental

Denver, CO

South Lakewood Dental, a regenerative dentistry practice in Lakewood, Colorado, offers ozone therapy and laser dentistry alongside comprehensive oral care. Ozone-supported procedures are used to supp…

  • Ozone Therapy
  • Laser Therapy (LLLT)
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Regulatory context

A note on Colorado's ozone therapy rules.

The "other" category is a catchall for regenerative wellness modalities with inconsistent federal oversight. Red light therapy devices (photobiomodulation) have narrow FDA 510(k) clearances for acne, muscle pain, and wound healing, not systemic regeneration. Whole-body cryotherapy is NOT FDA-approved for any medical indication and received an FDA safety communication in July 2016 warning of asphyxiation, frostbite, and burn risks. Ozone therapy is NOT FDA-approved for any medical use and the FDA has stated ozone is a toxic gas with no known useful medical application. Condition-specific regenerative offerings (hair restoration with minoxidil or finasteride, ED care beyond PDE5 inhibitors and shockwave) have varying approval depending on route and drug source.

  • Colorado Medical Practice Act (C.R.S. Title 12, Art. 240)
    Defines scope of medical practice and delegation rules to nurses and medical assistants in outpatient and wellness settings.
  • Colorado Natural Health Consumer Protection Act (C.R.S. § 6-1-724)
    Permits non-licensed complementary and alternative health practitioners to offer services with required disclosures, excluding procedures that penetrate the skin.

The Colorado Medical Board investigates unlicensed medical practice, corporate practice violations, and false advertising by wellness clinics. Ozone and chelation clinics making disease-treatment claims have faced disciplinary action. The Department of Regulatory Agencies (DORA) consolidates oversight across medical, nursing, and pharmacy boards. Enforcement is moderate and complaint-driven. The Colorado Attorney General pursues deceptive health claims under the Colorado Consumer Protection Act.

Sources: fda.gov · dpo.colorado.gov · dpo.colorado.gov

Ozone Therapy in Denver, answered.

No. Ozone therapy is NOT FDA-approved for any medical use. The FDA issued a 1976 declaration stating ozone is a toxic gas with no known useful medical application, and that position has not changed. Clinics that offer ozone do so under physician clinical judgement, not under an approved indication. Many marketing claims for ozone are unsupported by high-quality clinical evidence, so any informed decision about booking a session should start with that clear disclosure.

Pricing in Denver typically runs $150 to $300 per session for standard major autohemotherapy (MAH), with prolozone joint injections, insufflation, and MinorAH often priced similarly or slightly lower. Higher-dose 10-pass ozone is considerably more expensive, usually $500 to $800 per session, with packages pushing totals into the thousands. Package pricing can lower the per-session rate but raises total spend. Remember that ozone is NOT FDA-approved, is not covered by insurance, and out-of-pocket cost is the norm.

Integrative practitioners commonly claim benefits for immune support, chronic infections such as Lyme disease and herpes, systemic inflammation, chronic fatigue, autoimmune conditions, and musculoskeletal pain using prolozone for joints and discs. The quality of clinical evidence supporting these claims is low, studies are often small or uncontrolled, and ozone therapy is NOT FDA-approved for any of these indications. Treat strong claims with caution.

In Colorado, naturopathic doctors (NDs) are licensed and operate under a broader scope than in most states, and many ozone providers are NDs working alongside MDs and DOs. Chiropractors generally cannot administer intravenous ozone, and scope varies by state medical and naturopathic board positions. Regardless of license type, verify active state licensure before any appointment, and remember that ozone therapy is NOT FDA-approved and is offered under physician clinical judgement rather than any approved indication.

Verify that the lead clinician holds an active state license, ask for written informed consent that clearly states ozone is NOT FDA-approved, and look for realistic evidence framing rather than cure claims. Avoid clinics that promise to cure cancer, autoimmune disease, or chronic infection. Membership in groups such as the AAOT is a peer-community signal, not an FDA credential, and should never substitute for verifying licensure and reading consent forms.

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