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Read the Ketamine Therapy guide for the educational context behind this treatment category.
Denver, CO
Ketamine Therapy clinics in Denver
A ketamine treatment center in Denver can be a psychiatric office, an infusion suite, or a wellness clinic, and the first thing to confirm is the delivery method: an intramuscular injection goes into a muscle, while an intravenous infusion delivers medication through a vein. Denver ketamine therapy options include offices around Cherry Creek near Colorado Boulevard and offerings west in Lakewood, where muscle injections are available. Some centers describe themselves as serving the wider Denver metro, including Aurora and Boulder along US-36, so a search result can point to a suburban address. Confirm where each appointment happens, compare travel along Colorado Boulevard and I-25 with trips toward Lakewood, and arrange an adult escort home.
Expect injection treatment in a medical or psychiatric office, with licensed medical staff administering medication and monitoring recovery. People typically seek out a ketamine treatment center after standard care for depression, anxiety, PTSD, or certain chronic pain conditions has not helped enough, and a Denver clinic should ask why you are seeking this treatment rather than assume it fits every diagnosis. An initial consultation should review your diagnosis, previous treatments, medications, blood pressure, and substance use history. Ask who prescribes, who stays available during treatment, and what training the team has in managing breathing problems or severe distress. Confirm whether psychotherapy is included or arranged separately.
Before booking, request the medication's formulation and source, plus written information about side effects, risks, and discharge instructions. Ketamine is a legal prescription medication when administered by licensed clinicians, though using it for depression, anxiety, or other mental health conditions is off-label, meaning the FDA has not specifically approved that use. Ask how follow-up tracks symptoms, who handles concerns between visits, and when treatment would change if it does not help. A written quote should distinguish assessment, medication, monitoring, psychotherapy, and follow-up, with additional charges identified. Evidence about sustained benefit remains limited, and this is usually cash pay.
Regenerated.com does not sell organic listing order or paid ranking within it. Featured placements are labeled and limited in number, while Verified indicates credential checks rather than spending. The directory is free for patients, and inclusion does not endorse a provider or treatment.
The national ketamine therapy hub explains how the medication works and reviews the broader evidence. Use How to read a Regenerated city hub and Featured vs Verified vs organic to understand the directory's comparison tools and labels.
30 Clinics,
Axis Integrated Mental Health
- Transcranial Magnetic Stimulation (TMS)
- Ketamine Therapy
Heartmind Medicine
- Neurofeedback Therapy
- Ketamine Therapy
- Psychedelic Therapy
Infusion IV Lounge
- NAD IV Therapy
- Vitamin IV Therapy
- IV Therapy
- IV Hydration
- Ketamine Therapy
Shadid Integrative Psychiatry - Nicole Shadid M.D.
- Biofeedback Therapy
- Neurofeedback Therapy
- Ketamine Therapy
- Psychedelic Therapy
- Hormone Replacement Therapy (HRT)
Dana McDowell New Beginnings Psychotherapy Ketamine-Assisted Psychotherapy
- Ketamine Therapy
Regulatory context
A note on Colorado's ketamine therapy rules.
Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.
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Colorado Proposition 122 / Natural Medicine Health Act (2022)
Decriminalized personal use of psilocybin, psilocyn, DMT, ibogaine, and mescaline (non-peyote) for adults 21+; authorized state-licensed Healing Centers for psilocybin-assisted therapy, with MDMA access permitted by state rule after June 2026. -
SB 23-290 Natural Medicine Regulation and Legalization
Implementing legislation establishing the Natural Medicine Division within DORA and the licensure framework for facilitators, healing centers, cultivators, and product manufacturers.
Colorado Healing Centers began licensing and operating in late 2024 and early 2025. The Colorado Department of Regulatory Agencies (DORA) Natural Medicine Division oversees facilitator licensure, healing center operations, testing, and track-and-trace. Federal law still classifies psilocybin as Schedule I, so DEA enforcement risk remains theoretical. The Colorado Medical Board regulates ketamine prescribing. Ryan Haight Act applies to telehealth ketamine.
Ketamine Therapy in Denver, answered.
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Explore statewide
Ketamine Therapy in ColoradoNationwide
Ketamine Therapy clinics across the US