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30 Best Ketamine Therapy Clinics in Denver, Colorado

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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What does this directory page list?

This page lists directory records associated with Ketamine Therapy in the Denver, Colorado browsing area. A browsing area can include nearby municipalities. Confirm each clinic's street address and current services directly.

Matching records:
30. Source: the current directory result set, including pages beyond this screen.
Treatment filter:
Ketamine Therapy.
Source limits:
Listing information is not an independent clinic evaluation. Record updates do not establish field-level check dates.

Read the Ketamine Therapy guide for the educational context behind this treatment category.

Denver, CO

Ketamine Therapy clinics in Denver

A ketamine treatment center in Denver can be a psychiatric office, an infusion suite, or a wellness clinic, and the first thing to confirm is the delivery method: an intramuscular injection goes into a muscle, while an intravenous infusion delivers medication through a vein. Denver ketamine therapy options include offices around Cherry Creek near Colorado Boulevard and offerings west in Lakewood, where muscle injections are available. Some centers describe themselves as serving the wider Denver metro, including Aurora and Boulder along US-36, so a search result can point to a suburban address. Confirm where each appointment happens, compare travel along Colorado Boulevard and I-25 with trips toward Lakewood, and arrange an adult escort home.

Expect injection treatment in a medical or psychiatric office, with licensed medical staff administering medication and monitoring recovery. People typically seek out a ketamine treatment center after standard care for depression, anxiety, PTSD, or certain chronic pain conditions has not helped enough, and a Denver clinic should ask why you are seeking this treatment rather than assume it fits every diagnosis. An initial consultation should review your diagnosis, previous treatments, medications, blood pressure, and substance use history. Ask who prescribes, who stays available during treatment, and what training the team has in managing breathing problems or severe distress. Confirm whether psychotherapy is included or arranged separately.

Before booking, request the medication's formulation and source, plus written information about side effects, risks, and discharge instructions. Ketamine is a legal prescription medication when administered by licensed clinicians, though using it for depression, anxiety, or other mental health conditions is off-label, meaning the FDA has not specifically approved that use. Ask how follow-up tracks symptoms, who handles concerns between visits, and when treatment would change if it does not help. A written quote should distinguish assessment, medication, monitoring, psychotherapy, and follow-up, with additional charges identified. Evidence about sustained benefit remains limited, and this is usually cash pay.

Regenerated.com does not sell organic listing order or paid ranking within it. Featured placements are labeled and limited in number, while Verified indicates credential checks rather than spending. The directory is free for patients, and inclusion does not endorse a provider or treatment.

The national ketamine therapy hub explains how the medication works and reviews the broader evidence. Use How to read a Regenerated city hub and Featured vs Verified vs organic to understand the directory's comparison tools and labels.

30 Clinics, showing page 1 of 2

Emotion Alchemy Collective Therapy
(5)
Physician status unknown

Emotion Alchemy Collective Therapy

Denver, CO

Emotion Alchemy Collective Therapy, a ketamine and psychedelic-assisted therapy clinic in Denver, specializes in treatment-resistant depression, anxiety, and trauma using evidence-based protocols. Th…

  • Ketamine Therapy
  • Psychedelic Therapy
The Ardent Grove Foundation
(8)
Physician status unknown

The Ardent Grove Foundation

Denver, CO

The Ardent Grove Foundation, a non-profit mental health clinic in Denver, specializes in ketamine-assisted therapy for treatment-resistant depression, anxiety, and trauma-related conditions. Operatin…

  • Ketamine Therapy
Summit Ketamine Innovations
(23)
Physician status unknown

Summit Ketamine Innovations

Denver, CO

Summit Ketamine Innovations, a ketamine-therapy clinic in Denver, offers intravenous and intramuscular ketamine treatment for treatment-resistant depression, anxiety, PTSD, trauma, obsessive-compulsi…

  • Ketamine Therapy
  • Migraine Treatment
Klarisana
(213)
Physician reported in record

Klarisana

Denver, CO

Klarisana, a ketamine-therapy clinic in Denver, specializes in ketamine and esketamine (Spravato) infusions for treatment-resistant depression, anxiety, PTSD, and chronic pain. The clinic combines ke…

  • Ketamine Therapy
Axis Integrated Mental Health
(206)
Physician status unknown

Axis Integrated Mental Health

Denver, CO

Axis Integrated Mental Health in Aurora offers ketamine therapy for treatment-resistant depression, anxiety, and related mood conditions. The clinic integrates ketamine protocols with psychiatric car…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Heartmind Medicine
(1)
Physician reported in record

Heartmind Medicine

Denver, CO

Heartmind Medicine, a ketamine-therapy clinic in Denver, specializes in ketamine-assisted psychotherapy and psychedelic-therapy protocols for treatment-resistant depression, anxiety, and related ment…

  • Neurofeedback Therapy
  • Ketamine Therapy
  • Psychedelic Therapy
Mile High Behavioral Healthcare
(31)
Physician status unknown

Mile High Behavioral Healthcare

Denver, CO

Mile High Behavioral Healthcare, a Ketamine Therapy Clinic in Denver, offers ketamine-assisted psychotherapy for treatment-resistant depression, anxiety, PTSD, and related mental-health conditions. T…

  • Ketamine Therapy
Beyond the Mind Psychotherapy
(2)
Physician status unknown

Beyond the Mind Psychotherapy

Denver, CO

Beyond the Mind Psychotherapy, a ketamine and psychedelic-assisted therapy clinic in Denver, offers evidence-based treatment for trauma, complex PTSD, and treatment-resistant depression. The practice…

  • Ketamine Therapy
  • Psychedelic Therapy
Rooted Rhythm Therapy
(30)
Physician status unknown

Rooted Rhythm Therapy

Denver, CO

Rooted Rhythm Therapy, a mental-health clinic in Denver, offers ketamine therapy alongside play-based and evidence-based approaches for children, teens, and families. The practice specializes in neur…

  • Ketamine Therapy
Infusion IV Lounge
(239)
Physician status unknown

Infusion IV Lounge

Denver, CO

Infusion IV Lounge, an IV therapy clinic in Denver, offers customized intravenous protocols including Myers Cocktail, NAD+ therapy, IV Hydration, and high-dose vitamin C infusions. The clinic special…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • IV Hydration
  • Ketamine Therapy
Shadid Integrative Psychiatry - Nicole Shadid M.D.
(5)
Physician reported in record

Shadid Integrative Psychiatry - Nicole Shadid M.D.

Denver, CO

Shadid Integrative Psychiatry, led by Nicole Shadid, M.D., a psychiatrist board-certified in adult psychiatry, integrative and holistic medicine, and functional medicine, offers ketamine therapy and …

  • Biofeedback Therapy
  • Neurofeedback Therapy
  • Ketamine Therapy
  • Psychedelic Therapy
  • Hormone Replacement Therapy (HRT)
The Catalyst Center
(14)
Physician reported in record

The Catalyst Center

Denver, CO

The Catalyst Center, a mental-health clinic in Denver, specializes in ketamine-assisted psychotherapy and psychedelic-assisted therapy for treatment-resistant depression, anxiety, PTSD, and related c…

  • Neurofeedback Therapy
  • Ketamine Therapy
Peak Interactive Wellness
(202)
Physician status unknown

Peak Interactive Wellness

Denver, CO

Peak Interactive Wellness, a ketamine-therapy clinic in Denver, offers ketamine-assisted psychotherapy for treatment-resistant depression, anxiety, and PTSD alongside comprehensive psychiatric diagno…

  • Ketamine Therapy
Denver Zen Den
(60)
Physician status unknown

Denver Zen Den

Denver, CO

Denver Zen Den, a Ketamine Therapy Clinic in Denver, offers ketamine-assisted therapy in a clinical setting. The practice positions itself as a sober psychedelic clinic, meaning treatments are conduc…

  • Ketamine Therapy
results per page

Regulatory context

A note on Colorado's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • Colorado Proposition 122 / Natural Medicine Health Act (2022)
    Decriminalized personal use of psilocybin, psilocyn, DMT, ibogaine, and mescaline (non-peyote) for adults 21+; authorized state-licensed Healing Centers for psilocybin-assisted therapy, with MDMA access permitted by state rule after June 2026.
  • SB 23-290 Natural Medicine Regulation and Legalization
    Implementing legislation establishing the Natural Medicine Division within DORA and the licensure framework for facilitators, healing centers, cultivators, and product manufacturers.

Colorado Healing Centers began licensing and operating in late 2024 and early 2025. The Colorado Department of Regulatory Agencies (DORA) Natural Medicine Division oversees facilitator licensure, healing center operations, testing, and track-and-trace. Federal law still classifies psilocybin as Schedule I, so DEA enforcement risk remains theoretical. The Colorado Medical Board regulates ketamine prescribing. Ryan Haight Act applies to telehealth ketamine.

Ketamine Therapy in Denver, answered.

An intramuscular injection delivers ketamine into a muscle; an IV infusion delivers it gradually through a vein. Denver-area providers may offer one route without the other, so confirm the method before scheduling. An infusion can be adjusted or stopped during delivery, while an injected dose cannot be withdrawn. Both require screening, monitoring, and recovery arrangements. Nasal esketamine is a separate treatment with different eligibility and administration requirements.

Ketamine injections and infusions for depression are commonly cash pay, although coverage depends on the service and insurance plan. Assessment, psychotherapy, or nasal esketamine may have different benefits. Request an itemized quote covering medication, administration, monitoring, therapy, testing, and follow-up, then confirm coverage with your insurer. This Denver page does not publish averages because delivery methods, staffing, and included services differ enough to make a single figure misleading.

Adults whose depression has not improved adequately with standard care may be considered after a medical and psychiatric assessment. Uncontrolled blood pressure, unstable heart disease, active psychotic symptoms, or pregnancy may mean postponing treatment or choosing another approach. Some programs also explore ketamine for bipolar depression or alongside addiction treatment, but eligibility and protocols for those uses differ from standard depression care, so ask how your diagnosis is addressed. A Denver clinician should explain the reason for recommending ketamine and coordinate with whoever manages your ongoing mental health care.

Research supports short-term symptom improvement for some adults with treatment-resistant depression, particularly with IV ketamine. Response varies, and improvement may fade. Evidence for muscle injections is less developed than for IV treatment, and questions remain about maintenance treatment and long-term harms. Ketamine itself is not FDA approved for psychiatric conditions; nasal esketamine has specific depression indications. Ask how the evidence applies to your diagnosis and proposed delivery method.

Care should begin with assessment, informed consent, and agreed goals, followed by monitored treatment and recovery before discharge. Dosing and session counts, including whether a lower microdose approach is used, are set after assessment and vary by clinic, which is why this page does not publish fixed schedules. Many offices use a quiet room with dimmed lighting or music for comfort. Ask whether psychotherapy and follow-up happen at the same Denver-area office, arrange an adult escort, and obtain a contact for concerns between appointments.

Possible effects include nausea, dizziness, sleepiness, increased blood pressure, and dissociation, a feeling of being detached from yourself or your surroundings. Breathing problems and intense psychological distress can occur, and repeated exposure raises concerns about bladder symptoms and misuse. Ask how staff monitor you, respond to complications, and decide when you can leave. Written instructions should explain which symptoms need urgent medical attention after discharge.

Get the names and professional roles of the prescriber, administering clinician, and any therapist. Use Colorado's Department of Regulatory Agencies license lookup to check current status and available disciplinary records. Ask about psychiatric assessment, monitoring, and emergency response training. Unlike a general web search, this page groups Denver-area options for comparison; the national hub covers mechanisms and evidence. Neither a listing nor a license check establishes suitability for your needs.

Featured identifies a labeled promotional placement, and those spaces are capped. Verified means credentials have been checked, not that a provider has paid more or will achieve a particular result. Organic order is not sold. Compare delivery method, clinical supervision, follow-up, and the actual treatment address alongside these labels. Regenerated.com is free for patients, and directory inclusion is not an endorsement of a clinician or treatment.

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