9 Best Lyme Disease Treatment Clinics in Tennessee

Tennessee residents searching for Lyme disease treatment, including those in Knoxville, generally find more options in the state's larger metro areas than in smaller towns and rural counties. Nashville and Memphis carry the bulk of the state's specialty and integrative medical practices, and Knoxville and Chattanooga in East Tennessee add a meaningful second tier. Someone outside those four metro areas should expect to travel, and should weigh whether a local primary care practice can start the workup first.

Tennessee has no statute written specifically for Lyme disease treatment; the general scope of practice that governs any infusion, prescription or supervised therapy in the state applies instead. Diagnosis and prescribing are handled by physicians, physician assistants or nurse practitioners within their licensed scope, and any infusion is typically given by a nurse under a physician's order. Lyme disease treatment is most often delivered through a primary care, infectious disease, or integrative medicine office rather than a dedicated specialty center, and if a clinic proposes an infusion suite, ask who orders and administers it.

Before booking anywhere in Tennessee, check the prescribing clinician's license with the Tennessee Board of Medical Examiners for physicians and physician assistants, or the Tennessee Board of Nursing for nurses. A license lookup confirms the credential is active and shows public disciplinary history, but it will not tell you whether a treatment plan is right for your case.

Ask any Tennessee clinic what is being administered, where it comes from, and for a written explanation of risks before you agree to anything. Ask who supervises the visit, what a quote itemizes line by line, and what happens if symptoms do not improve, since a workable plan should include a clear next step rather than an open-ended series of visits.

The clinics listed on this page appear in an order that is not for sale, and any Featured listing is labeled and capped rather than hidden among organic results. Verified on this page means the clinic completed credential checks, not that it paid for the label, and inclusion in this directory is not an endorsement of any clinic, physician or treatment claim. Regenerated.com is free for patients. For how Lyme disease treatment works and what the evidence supports, see the national hub, and for help reading this list, read How to read a Regenerated city hub and Featured vs Verified vs organic.