What does this directory page list?
Read the Ketamine Therapy guide for the educational context behind this treatment category.
Plano, TX
Ketamine Therapy clinics in Plano
Anyone searching for ketamine psychotherapy in Plano, Texas is usually looking for a provider who pairs ketamine with structured talk therapy rather than a stand-alone infusion. This approach is sometimes called ketamine-assisted psychotherapy, with a licensed therapist involved before, during, or after dosing. A ketamine therapy listing does not automatically mean psychotherapy is included: ask whether the prescriber and therapist work together or counseling requires a separate referral.
Compare each listed address with your route through Plano, particularly Preston Road, the Dallas North Tollway and the US-75 Central Expressway corridor. Legacy West and the surrounding Legacy Business Park are useful west-side landmarks, but confirm where both medication and counseling appointments happen. For trips from Frisco or Allen, check whether the Sam Rayburn Tollway or US-75 fits the actual address. Arrange an escort home after dosing and allow time for monitoring before departure.
Office-based care generally takes place in a physician's office or dedicated treatment room, with medical staff monitoring dosing and a licensed therapist providing psychotherapy. A first visit typically includes a psychiatric and medical history, a discussion of prior treatment, and a plan for how therapy will be timed around dosing. Follow up involves ongoing check-ins rather than a fixed number of visits. Ask how an initial course is reviewed before considering maintenance, and who handles concerns between appointments.
Before booking, ask who prescribes and administers, what formulation is used, which pharmacy or manufacturer supplies it, and how risks are disclosed in writing. IV ketamine for depression is off-label; nasal esketamine has specific approved depression indications and separate monitoring requirements, and neither automatically includes psychotherapy. Ask what happens if symptoms do not improve, and request a written quote separating medical visits, medication, monitoring and therapy, since these may be billed independently and IV treatment is commonly cash pay.
Organic order is not paid ranking, Featured slots are labeled and capped, and Verified means a provider's credentials have been checked rather than that they paid for the label. Regenerated.com is free for patients, and inclusion is not an endorsement. The national ketamine therapy hub covers how treatment works and the evidence, including uncertainty about lasting benefit and the added value of psychotherapy. See How to read a Regenerated city hub and Featured vs Verified vs organic.
5 Clinics
Southwest Pain Management
- Ketamine Therapy
- Arthritis Treatment
- Migraine Treatment
- Hormone Replacement Therapy (HRT)
Dean Center for Integrative Medicine and Wellness (DCIMW)
- PRP Therapy
- IV Therapy
- Ketamine Therapy
- Arthritis Treatment
- Migraine Treatment
Heading Health Ketamine Center
- Transcranial Magnetic Stimulation (TMS)
- Ketamine Therapy
Precision Wellness Center
- IV Hydration
- Ketamine Therapy
- Peptide Therapy
- Hormone Replacement Therapy (HRT)
- NAD IV Therapy
Regulatory context
A note on Texas's ketamine therapy rules.
Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.
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HB 1802 / Psilocybin and MDMA Research (2021)
Required Texas Health and Human Services Commission to study psilocybin and MDMA for PTSD treatment in veterans; report completed. -
Texas Ibogaine Initiative (HB 3717, 2025 pending)
Would allocate $50 million for FDA-regulated ibogaine clinical trials, potentially the largest state psychedelic research investment in US history. -
Texas Controlled Substances Act
Mirrors federal scheduling.
Texas enforces federal scheduling. The Texas Medical Board oversees prescriber conduct. DEA enforcement on ketamine clinics focuses on diversion and Ryan Haight Act telehealth rules. Texas PMP requires controlled substance reporting. Texas has seen rapid ketamine clinic growth in Austin, Dallas, and Houston markets with corresponding enforcement attention on compounding and telehealth practices.
Ketamine Therapy in Plano, answered.
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- Arthritis Treatment in Plano
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- Hormone Replacement Therapy (HRT) in Plano
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- IV Therapy in Plano
- Migraine Treatment in Plano
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- Peptide Therapy in Plano
- PRP Therapy in Plano
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Ketamine Therapy in TexasNationwide
Ketamine Therapy clinics across the US