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8 Best Ketamine Therapy Clinics in Santa Monica, California

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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What does this directory page list?

This page lists directory records associated with Ketamine Therapy in the Santa Monica, California browsing area. A browsing area can include nearby municipalities. Confirm each clinic's street address and current services directly.

Matching records:
8. Source: the current directory result set, including pages beyond this screen.
Treatment filter:
Ketamine Therapy.
Source limits:
Listing information is not an independent clinic evaluation. Record updates do not establish field-level check dates.

Read the Ketamine Therapy guide for the educational context behind this treatment category.

Santa Monica, CA

Ketamine Therapy clinics in Santa Monica

Ketamine-assisted therapy in Santa Monica generally means prescribed ketamine paired with structured psychotherapy, delivered by a prescriber and a licensed therapist working together, rather than ketamine alone given at a stand-alone infusion visit. Confirm whether a provider combines medication with psychotherapy sessions or offers medication appointments alone, since both are advertised under similar names locally. Local options include offices along Wilshire Boulevard, downtown near Sixth Street, the medical offices around 20th Street, and practices along Santa Monica Boulevard toward the Westwood border. Confirm the exact address before planning travel, especially when comparing Santa Monica with nearby West Los Angeles. Ask about parking, recovery time and arranging an escort home.

Ketamine therapy may take place in a psychiatric office, an infusion suite or a therapy practice working with a medical prescriber. For assisted psychotherapy, clarify who prescribes the medication, who administers it, who monitors you and whether a licensed therapist is present during treatment. An initial assessment should review your diagnosis, previous treatment, medications, medical history and blood pressure. Preparation and later integration visits, where you discuss the experience and its relevance to daily life, may be separate appointments or involve another clinician.

Before booking, request the medication's name, formulation, route and source, including the dispensing pharmacy when relevant. Ask for written information about risks and side effects, the supervising clinician's credentials and the response plan for a medical problem. Agree on how symptoms will be tracked, who handles concerns between visits and what happens if treatment does not help. A written quote should identify assessment, medication, monitoring, psychotherapy and follow-up charges, including anything billed separately. Ketamine for depression is not FDA approved for that use and is commonly cash pay; evidence about lasting benefit and the added value of combining it with psychotherapy remains limited.

Regenerated.com is free for patients, and payment cannot buy organic listing order. Featured placements are labeled and capped, while Verified means credential checks, not provider spending. Inclusion in this directory does not endorse a provider or a treatment.

The national ketamine therapy hub explains the proposed mechanism and broader evidence. For help interpreting local results, read How to read a Regenerated city hub and Featured vs Verified vs organic.

8 Clinics

(39)
Physician status unknown

Golden Afternoon Ketamine Clinic - Los Angeles

Santa Monica, CA

Golden Afternoon Ketamine Clinic, located in Santa Monica, specializes in ketamine therapy and intranasal esketamine (Spravato) for treatment-resistant depression, anxiety, and PTSD. The clinic offer…

  • IV Therapy
  • Ketamine Therapy
BioReset Medical
(1)
Physician reported in record

BioReset Medical

Santa Monica, CA

BioReset Medical, a regenerative-medicine clinic in Santa Monica, offers stem-cell therapy, platelet-rich plasma injections, and peptide protocols alongside IV nutrient therapy, NAD infusions, and oz…

  • PRP Therapy
  • Ozone Therapy
  • IV Therapy
  • Ketamine Therapy
  • Arthritis Treatment
Golden Afternoon Ketamine Clinic - Los Angeles
Physician reported in record

Golden Afternoon Ketamine Clinic - Los Angeles

Santa Monica, CA

Golden Afternoon Ketamine Clinic, in Santa Monica, specializes in ketamine and esketamine therapy for treatment-resistant depression, anxiety, and related conditions. The clinic offers intravenous ke…

  • IV Therapy
  • Ketamine Therapy
  • Stem Cell Therapy
Source Healthcare
(151)
Physician status unknown

Source Healthcare

Santa Monica, CA

Source Healthcare, a regenerative-medicine clinic in Santa Monica, specializes in pain management using ketamine infusion therapy and platelet-rich plasma injections alongside conventional interventi…

  • PRP Therapy
  • Ketamine Therapy
  • Arthritis Treatment
LifeSpan medicine
(12)
Physician reported in record

LifeSpan medicine

Santa Monica, CA

LifeSpan Medicine, an integrative longevity clinic in Santa Monica, offers regenerative medicine alongside supportive therapies including IV nutrient infusions, peptide protocols, and hormone optimiz…

  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy
  • Ketamine Therapy
California Pain Medicine Center
Physician reported in record

California Pain Medicine Center

Santa Monica, CA

California Pain Medicine Center, located in Santa Monica, offers ketamine infusion therapy and platelet-rich plasma injections alongside conventional pain-management procedures for patients with acut…

  • PRP Therapy
  • Biofeedback Therapy
  • Ketamine Therapy
  • Arthritis Treatment
Home-LA Psychiatry & Ketamine Therapy
(11)
Physician status unknown

Home-LA Psychiatry & Ketamine Therapy

Santa Monica, CA

Home-LA Psychiatry & Ketamine Therapy, based in Santa Monica, specializes in ketamine-assisted therapy for treatment-resistant depression, anxiety, and PTSD. The clinic combines ketamine protocols wi…

  • PRP Therapy
  • Ketamine Therapy
  • Arthritis Treatment
Source Healthcare
(19)
Physician reported in record

Source Healthcare

Santa Monica, CA

Source Healthcare in Santa Monica offers stem-cell therapy, platelet-rich plasma injections, and regenerative-medicine protocols for chronic musculoskeletal pain and sports injuries. The practice com…

  • PRP Therapy
  • Ketamine Therapy
  • Arthritis Treatment
  • Stem Cell Therapy
results per page

Regulatory context

A note on California's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • SB 803 (2023, vetoed) and SB 1012 (2024, stalled)
    Proposed regulated therapeutic access to psilocybin, MDMA, mescaline, and DMT; Governor Newsom vetoed SB 58 (2023) citing lack of treatment guidelines.
  • Local decriminalization resolutions
    Oakland (2019), Santa Cruz (2020), Arcata, San Francisco, and Berkeley have passed non-binding resolutions deprioritizing enforcement of natural psychedelics; no legal therapeutic framework.

California enforces federal DEA scheduling. The Medical Board of California investigates prescriber misconduct, including ketamine diversion and inadequate patient monitoring. Several high-profile California ketamine-related deaths (including Matthew Perry's 2023 overdose) have intensified board scrutiny of clinic practices. DEA enforcement targets compounding, diversion, and Ryan Haight Act telehealth compliance.

Ketamine Therapy in Santa Monica, answered.

Ketamine-assisted psychotherapy combines prescribed ketamine with psychological support, which can include preparation, support during dosing and later integration conversations. A Santa Monica infusion appointment does not automatically include psychotherapy. Ask whether the therapist and prescriber work together, where medication is administered and which visits involve each professional. An intake should explain the treatment goals and how the plan fits your existing mental health care.

Ketamine treatment for depression is commonly cash pay, while coverage for psychotherapy, evaluations or nasal esketamine depends on the service and your plan. Medication route, staffing, monitoring and therapist involvement affect the total. Request an itemized quote covering assessment, medication, administration, recovery monitoring, therapy and follow-up, then check benefits with your insurer. This Santa Monica page does not publish an average because different treatment formats and billing arrangements are not directly comparable.

Adults whose depression has not improved enough with established treatments may be considered after medical and psychiatric screening. Pregnancy, uncontrolled blood pressure or a history of psychosis may lead a clinician to recommend waiting or another treatment. Substance use history also needs careful review. A Santa Monica assessment should explain the reasoning for the recommendation, discuss alternatives and establish coordination with your usual clinician before treatment begins.

IV treatment delivers ketamine through a vein while clinical staff monitor your condition and vital signs. The plan should include screening, informed consent, preparation instructions, observation during recovery and discharge criteria. Further appointments should depend on symptom changes, tolerability and clinical review rather than an automatic commitment to ongoing treatment. Confirm whether psychotherapy is included, who answers concerns afterward and how your escort should arrange pickup at the Santa Monica office.

Ask about nausea, dizziness, sedation, increased blood pressure and dissociation, which can feel like being detached from your body or surroundings. Breathing problems and misuse are also concerns, and repeated exposure can carry urinary risks. Request written information about monitoring and symptoms that require urgent attention. Discuss other medications and alcohol use with the prescriber, and follow discharge instructions about driving and having someone accompany you home.

Get the prescriber's and therapist's names, license types and license numbers. Check physicians through the Medical Board of California or the Osteopathic Medical Board of California, as appropriate. Check psychologists through the California Board of Psychology and marriage and family therapists or clinical social workers through the Board of Behavioral Sciences. Confirm active status and any public disciplinary history. Ask who provides medical supervision, monitors treatment and responds to emergencies on site.

Research supports short-term symptom improvement for some adults with treatment-resistant depression, but individual response and durability vary. Evidence for long-term ketamine use and the additional benefit of pairing it with psychotherapy is less settled. Ketamine is not FDA approved for psychiatric conditions; nasal esketamine is a different medication with specific approved depression uses. Ask your Santa Monica clinician which evidence supports the exact formulation, route and treatment goal being proposed.

Use this local directory to compare treatment locations and services, then confirm details directly with each provider. The national hub covers mechanisms and evidence; a general web search may mix advertisements, remote services and offices outside Santa Monica. Organic order here is not sold, Featured slots are labeled and capped, and Verified means credential checks rather than spending. Patient access is free, and inclusion is not an endorsement or a prediction of treatment results.

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