14 Best Ketamine Therapy Clinics in Colorado Springs, Colorado

Adults in Colorado Springs researching ketamine therapy for treatment resistant depression are usually asking the same three things: where it is actually offered nearby, what a first visit involves, and how to tell a credentialed provider from a marketing claim. This page covers all three for this metro specifically, alongside the list of clinics below it.

Clinics offering ketamine therapy in Colorado Springs tend to cluster along the Powers Boulevard corridor on the east side and near Woodmen Road and Briargate to the north, with other practices located near Union Boulevard close to Memorial Hospital Central. A handful of providers sit along North Academy Boulevard or near I-25, which connects the metro to Monument, Fountain, and Pueblo. A Colorado Springs mailing address does not always mean an in-person treatment site, so confirm exactly where sessions take place.

For adults who have tried standard antidepressants and therapy without enough relief, which is what treatment resistant depression generally means, ketamine therapy here is typically delivered as an intravenous infusion in a monitored medical or psychiatric office, or as esketamine nasal spray given under direct observation. These are different protocols, so ask which one a clinic actually offers. A first visit should cover your psychiatric and medical history, current medications, blood pressure, substance use, and a review of what has already been tried. Later visits track mood, side effects, and function rather than following a number of sessions promised upfront.

Before booking, ask who prescribes and who administers treatment, what their licensure and supervision look like, where the medication comes from, and how side effects and risks are disclosed in writing. Ask what happens if symptoms do not improve and request a written quote that separates the evaluation, medication, administration, monitoring, any psychotherapy, and follow up visits.

How this page is ordered matters too. Organic listing order on Regenerated.com is never sold. Featured placements are clearly labeled and limited in number. A Verified badge reflects credential checks on a provider, not how much they paid. Regenerated.com is free for patients, and appearing in this directory is not an endorsement of any clinic or treatment.

The national ketamine therapy hub covers how the treatment works and what the broader evidence shows. For more on how this directory works, read How to read a Regenerated city hub and Featured vs Verified vs organic.