Chicago, IL
Ketamine Therapy clinics in Chicago
Chicago has multiple clinics offering ketamine therapy, a fast growing segment for treatment resistant depression, PTSD, chronic pain, and anxiety. Illinois requires DEA registration and IDFPR oversight for ketamine prescribing; Spravato REMS is available in major hospital systems. Most Chicago clinics deliver IV ketamine infusions in a monitored clinical setting, typically across a 6 session induction protocol, followed by maintenance infusions. Spravato (esketamine), the FDA approved nasal spray for treatment resistant depression, is available in Chicago only at REMS certified clinics and is often covered by insurance when medical necessity is documented. Compounded ketamine lozenges and troches are also prescribed in Chicago, sometimes through telehealth platforms like Mindbloom, Joyous, and Innerwell, subject to Ryan Haight Act and DEA special registration considerations. Local pricing in Chicago sits in the standard range: single IV infusions run 500 to 900 dollars, a full 6 session protocol lands at 3,000 to 5,400, and Spravato copays depend on insurance coverage. A reputable Chicago ketamine clinic will pair pharmacology with integration support, monitor vitals during infusion, and have a clear crisis and follow up plan.
Striver IV Vitamin Infusion
- NAD IV Therapy
- Vitamin IV Therapy
- IV Therapy
- IV Hydration
- Ketamine Therapy
Metropolitan Institute of Pain and Telehealth
- PRP Therapy
- Ketamine Therapy
- Arthritis Treatment
- Migraine Treatment
IV Solution
- IV Therapy
- Transcranial Magnetic Stimulation (TMS)
- Ketamine Therapy
- Migraine Treatment
- NAD IV Therapy
Quench Wellness
- Vitamin IV Therapy
- IV Therapy
- Ketamine Therapy
- Hormone Replacement Therapy (HRT)
Prime IV Hydration & Wellness (Chicago)
- NAD IV Therapy
- Vitamin IV Therapy
- IV Therapy
- IV Hydration
- Hyperbaric Oxygen Therapy (HBOT)
Glaser & Randhawa Mental Health Group
- Transcranial Magnetic Stimulation (TMS)
- Ketamine Therapy
SunCloud Health Outpatient Treatment Center
- Transcranial Magnetic Stimulation (TMS)
- Ketamine Therapy
TransformRX Wellness and Weight Loss
- IV Therapy
- Ketamine Therapy
- Peptide Therapy
- Testosterone Replacement Therapy (TRT)
- NAD IV Therapy
CNS Brain Center
- NAD IV Therapy
- Vitamin IV Therapy
- IV Therapy
- Transcranial Magnetic Stimulation (TMS)
- Hyperbaric Oxygen Therapy (HBOT)
Integrative Medical Pain Clinic- Dr. Linda Li
- NAD IV Therapy
- Vitamin IV Therapy
- PRP Therapy
- Ozone Therapy
- IV Therapy
Regulatory context
A note on Illinois's ketamine therapy rules.
Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.
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CURE Act / SB 3695 (introduced 2024)
Proposed Compassionate Use and Research of Entheogens Act to create a state psilocybin service center framework modeled on Oregon; pending. -
Illinois Controlled Substances Act
Mirrors federal scheduling.
Illinois enforces federal scheduling. The Illinois Department of Financial and Professional Regulation (IDFPR) oversees prescriber conduct. DEA enforcement on ketamine clinics focuses on diversion and Ryan Haight Act telehealth rules. Illinois PMP requires controlled substance reporting. Active legislative interest (CURE Act) has drawn regulatory attention but no current therapeutic access framework exists.