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34 Best Ozone Therapy Clinics in South Carolina

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Read the Ozone Therapy guide: evidence, costs and questions to ask

South Carolina

Ozone Therapy clinics in South Carolina

This page currently lists 34 ozone therapy clinics across South Carolina, and supply is spread unevenly across the state. Most clinics sit in the state's larger metro areas, particularly Charleston, Columbia and the Greenville-Spartanburg corridor, with a smaller presence around Myrtle Beach. Patients in the Midlands, the Pee Dee region or the Lowcountry outside those cities typically face a longer drive, and some South Carolina residents weigh crossing into North Carolina toward Charlotte or into Georgia toward the Augusta area when nothing close to home fits. Confirm the treatment address before booking, since a clinic's advertising region can extend well beyond where the office itself sits.

South Carolina does not set out a rule written specifically for ozone therapy. Who may administer it, and how closely that person must be supervised, follows the general scope of practice that applies to physicians, physician assistants and advanced practice nurses under the state's professional boards. In practice, ozone therapy in South Carolina is typically offered through a physician's office, an integrative medical practice or a wellness setting, and supervision varies from one clinic to the next, so confirm directly who will be present and who is responsible for your care.

Before booking anywhere in the state, check a clinician's standing with the South Carolina Board of Medical Examiners for physicians and physician assistants, or the South Carolina Board of Nursing for nurses and nurse practitioners. A license check confirms whether someone is currently licensed and discloses any public disciplinary history; it does not confirm that ozone therapy suits your diagnosis. Ask what is actually being administered, how the ozone is generated, how equipment is kept sterile, how risks are disclosed in writing, and what happens if treatment does not help. Request an itemized quote that separates consultation, testing, treatment and follow up.

Listing order on this page is not for sale. Featured placements are labeled and capped rather than mixed invisibly into the results, a Verified label reflects completed credential checks rather than how much a clinic has spent, and Regenerated.com is free for patients to use. Being listed here, in any position, is not an endorsement of a clinic or its claims.

For the proposed mechanism and the state of the evidence, consult the national ozone therapy hub. To understand how this list and its labels work, read How to read a Regenerated city hub and Featured vs Verified vs organic.

34 Clinics, showing page 2 of 3

Choose a Natural Way
(4)
Physician status unknown

Choose a Natural Way

Simpsonville, SC

Choose a Natural Way, a functional-medicine clinic in Simpsonville, South Carolina, specializes in integrative therapies aimed at supporting the body's own healing capacity. The clinic offers peptide…

  • Biofeedback Therapy
  • Ozone Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Arthritis Treatment
  • Peptide Therapy
InterveneMD
(9)
Physician status unknown

InterveneMD

Mount Pleasant, SC

InterveneMD, a regenerative-medicine clinic in Mt. Pleasant, offers platelet-rich plasma therapy, stem-cell protocols, and shockwave therapy for musculoskeletal and joint conditions alongside peptide…

  • PRP Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • IV Therapy
  • Laser Therapy (LLLT)
Infu-Zen Spa
(129)
Physician status unknown

Infu-Zen Spa

Lexington, SC

Infu-Zen Spa, a longevity and anti-aging clinic in Lexington, South Carolina, specializes in IV nutrient therapy and NAD IV therapy alongside Ozone Therapy. The clinic's focus is on supportive protoc…

  • Ozone Therapy
  • IV Hydration
  • NAD IV Therapy
Gesundheit Carolina
(4)
Physician status unknown

Gesundheit Carolina

Rock Hill, SC

Gesundheit Carolina, a functional and integrative medicine clinic in Inman, SC, offers Oxygen Therapy, Ozone Therapy, Peptide Therapy, and specialized Lyme Disease Treatment. The practice emphasizes …

  • Ozone Therapy
  • Oxygen Therapy
  • Lyme Disease Treatment
  • Peptide Therapy
Palmer Distinctive Dentistry
(576)
Physician status unknown

Palmer Distinctive Dentistry

Greenville, SC

Palmer Distinctive Dentistry, a biological dentistry practice in Anderson, South Carolina, offers ozone therapy and laser therapy (LLLT) alongside mercury-free restorative dentistry. The clinic prior…

  • Ozone Therapy
  • Laser Therapy (LLLT)
Avondale Family Dentistry
(15)
Physician status unknown

Avondale Family Dentistry

Charleston, SC

Avondale Family Dentistry, a regenerative dentistry practice in Charleston, specializes in ozone-supported dental procedures alongside comprehensive restorative and aesthetic care. The clinic integra…

  • Ozone Therapy
Merge Medical Center
(127)
Physician status unknown

Merge Medical Center

Mount Pleasant, SC

Merge Medical Center, a regenerative medicine clinic in Mt Pleasant, specializes in hormone replacement therapy with pellet implants, alongside prolotherapy and ozone-IV protocols for pain management…

  • Ozone Therapy
  • IV Therapy
  • Arthritis Treatment
  • Hormone Replacement Therapy (HRT)
MyBellis
Physician status unknown

MyBellis

Bluffton, SC

MyBellis, an integrative-medicine clinic in Beaufort, SC, offers IV nutrient therapy and vitamin infusions alongside supportive modalities including Ozone Therapy, Oxygen Therapy, and Cryotherapy. Th…

  • Vitamin IV Therapy
  • Ozone Therapy
  • IV Hydration
  • Oxygen Therapy
  • Cryotherapy
Karisma Health
(3)
Physician status unknown

Karisma Health

Inman, SC

Karisma Health, an integrative primary care clinic in Gaffney, South Carolina, offers IV therapy and ozone therapy alongside supportive services including infrared sauna and ionic foot bath. The prac…

  • Ozone Therapy
  • IV Therapy
  • IV Hydration
  • NAD IV Therapy
Better Life Carolinas
(21)
Physician reported in record

Better Life Carolinas

Mount Pleasant, SC

Better Life Carolinas, a longevity medicine practice in Mt. Pleasant, specializes in hormone optimization, peptide therapy, and regenerative orthobiologics for patients pursuing age-management and pe…

  • PRP Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
SomaSonder Wellness
(8)
Physician status unknown

SomaSonder Wellness

Greenville, SC

SomaSonder Wellness, a wellness clinic in Greenville, South Carolina, offers oxygen therapy, ozone therapy, and red-light therapy as core regenerative modalities. The practice frames treatment within…

  • Ozone Therapy
  • Oxygen Therapy
  • Lyme Disease Treatment
  • Red Light Therapy
Biological Center for Dentistry
(312)
Physician reported in record

Biological Center for Dentistry

Bluffton, SC

Biological Center for Dentistry in Bluffton, South Carolina specializes in biological dentistry with a focus on ozone therapy and laser dentistry. The practice employs ozone-supported procedures and …

  • Ozone Therapy
  • Laser Therapy (LLLT)
  • TMJ Treatment
AIM Acupuncture & Integrative Medicine
(130)
Physician reported in record

AIM Acupuncture & Integrative Medicine

North Myrtle Beach, SC

AIM Acupuncture & Integrative Medicine, located in North Myrtle Beach, South Carolina, offers acupuncture and functional-medicine consultations as entry points for patients with chronic pain, mobilit…

  • Ozone Therapy
Intervene MD
(115)
Physician status unknown

Intervene MD

Mount Pleasant, SC

Intervene MD, a regenerative medicine clinic in Mt Pleasant, offers platelet-rich plasma therapy, stem-cell protocols, and shockwave therapy for musculoskeletal and joint conditions. The clinic also …

  • PRP Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • IV Therapy
  • Laser Therapy (LLLT)
Freedom Integrative Wellness
(107)
Physician status unknown

Freedom Integrative Wellness

Tega Cay, SC

Freedom Integrative Wellness, a functional and integrative-medicine clinic in Fort Mill, SC, offers cell-based and regenerative therapies alongside conventional primary care. The practice specializes…

  • Vitamin IV Therapy
  • Ozone Therapy
  • IV Therapy
  • Chelation Therapy
  • Red Light Therapy
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Regulatory context

A note on South Carolina's ozone therapy rules.

The "other" category is a catchall for regenerative wellness modalities with inconsistent federal oversight. Red light therapy devices (photobiomodulation) have narrow FDA 510(k) clearances for acne, muscle pain, and wound healing, not systemic regeneration. Whole-body cryotherapy is NOT FDA-approved for any medical indication and received an FDA safety communication in July 2016 warning of asphyxiation, frostbite, and burn risks. Ozone therapy is NOT FDA-approved for any medical use and the FDA has stated ozone is a toxic gas with no known useful medical application. Condition-specific regenerative offerings (hair restoration with minoxidil or finasteride, ED care beyond PDE5 inhibitors and shockwave) have varying approval depending on route and drug source.

  • South Carolina Medical Practice Act (S.C. Code Ann. § 40-47)
    Defines practice of medicine and delegation rules for wellness settings.
  • South Carolina Board of Medical Examiners Regulations (S.C. Regs. 81)
    Governs physician oversight of injectables, lasers, and device-based procedures.

The South Carolina Department of Labor, Licensing and Regulation and the Board of Medical Examiners investigate unlicensed practice and scope violations. Ozone and chelation clinics making disease-treatment claims risk board action. The Attorney General pursues deceptive health claims under the South Carolina Unfair Trade Practices Act. Enforcement is moderate and complaint-driven.

Ozone Therapy in , answered.

Ozone therapy in South Carolina is concentrated in the state's larger metro areas, mainly Charleston, Columbia and the Greenville-Spartanburg corridor, with fewer options around Myrtle Beach and little presence in much of the Midlands or Pee Dee region. If you live outside those metros, plan for a drive of an hour or more, or compare options just across the state line in Charlotte or the Augusta, Georgia area before committing to a repeat treatment schedule.

Ozone therapy is generally cash pay in South Carolina because it is marketed for uses outside FDA approval, so check directly with your insurer rather than assuming coverage. Price depends on the delivery method, the setting, any testing and whether other treatments are added. Ask for an itemized quote that separates consultation, testing, treatment and follow up. This page does not publish an average cost because bundled services vary too much to make one figure meaningful.

South Carolina does not set a rule written specifically for ozone therapy. Who may administer it and how closely they must be supervised follows the general scope of practice that applies to physicians, physician assistants and advanced practice nurses under the state's professional boards. That means supervision and setting can vary from one clinic to the next, so confirm directly who will be present during your treatment and who is responsible for your care.

Physicians and physician assistants can be checked through the South Carolina Board of Medical Examiners, and nurses and nurse practitioners through the South Carolina Board of Nursing. Both let you confirm whether a license is active and review any public disciplinary history. Neither check tells you whether ozone therapy suits your diagnosis or how a specific clinic operates, so treat it as one step among several before booking.

There is no established candidate profile for ozone therapy marketed for general wellness use, so a South Carolina clinician should review your diagnosis, medical history, medications and the specific procedure proposed before discussing suitability. People who are pregnant or who have significant blood, heart or lung conditions typically warrant extra caution and a conversation with their treating physician first. New, unexplained or worsening symptoms call for medical evaluation rather than booking a treatment package.

Ozone therapy and hyperbaric oxygen therapy are different procedures with different delivery methods and different, often overlapping, marketing claims, and neither substitutes for the other without a clinician reviewing your specific situation. Some South Carolina clinics also offer to pair ozone therapy with injectable treatments such as PRP, but combining treatments does not by itself show added benefit for a given diagnosis. Ask whether each addition is actually indicated, and confirm it is priced and consented separately.

This page covers ozone therapy across the whole state rather than one metro, so it is built for deciding where in South Carolina to look or whether to travel, not for comparing addresses within a single city. A general web search mixes advertising, directories and unrelated results together. The national ozone therapy hub covers the mechanism and evidence, while a city page, where one exists, covers local detail this state view intentionally leaves out.

This page does not rank clinics by quality, so "best" is not a label Regenerated.com applies to any listing. Organic order on this list is not sold, and Featured placements are labeled and capped rather than blended invisibly into the results. A Verified label reflects completed credential checks rather than spend. Reviews and reputation are worth researching independently, but being listed here, in any position, is not an endorsement of a clinic or its claims.

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