11 Best Ketamine Therapy Clinics in San Antonio, Texas (2026)

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This page lists directory records associated with Ketamine Therapy in the San Antonio, Texas browsing area. A browsing area can include nearby municipalities. Confirm each clinic's street address and current services directly.

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Ketamine Therapy.

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Listing information is not an independent clinic evaluation. Record updates do not establish field-level check dates.

Read the Ketamine Therapy guide for the educational context behind this treatment category.

Ketamine Therapy clinics in San Antonio

Ketamine treatment in San Antonio is offered by psychiatric practices, infusion suites and wellness clinics, so check where a provider actually sees patients, since many groups are headquartered elsewhere and only hold hours locally. The South Texas Medical Center, around Fredericksburg Road, Floyd Curl Drive and Babcock Road near Loop 410, is the city's main medical and infusion suite cluster. Stone Oak, along US-281 North, has newer wellness and behavioral health offices serving the fast-growing north side. Downtown, the Pearl area and Alamo Heights add fewer practices, reached via I-10 or I-35. Confirm the exact address before booking.

Ketamine therapy locally is generally delivered as a monitored intravenous infusion in a medical office, with a prescriber and clinical staff present throughout. A first visit should include a psychiatric and medical history, current medications, and blood pressure and cardiac screening, with a clear explanation of what is being administered. Follow up typically involves symptom tracking and a clinician review before further sessions are discussed, without a fixed count promised in advance. Most San Antonio referrals start with depression that has not improved enough with standard medication and talk therapy, and some practices also see patients for anxiety or PTSD, including veterans, with evidence varying by use. A smaller number of local offices offer nasal esketamine as an alternative to infusion, given under direct observation rather than taken home.

Before booking, ask about the prescriber's license and supervision, where the medication comes from, how side effects and risks are disclosed in writing, what happens if symptoms do not improve, and which parts of a quote are included versus billed separately. Ask whether the infusion room offers music or dimmed lighting, a detail many local practices offer. Arrange for someone to drive you home afterward.

Listing order here is not paid ranking: organic position is not for sale, Featured placements are labeled and capped, and Verified reflects credential checks rather than advertising spend. Regenerated.com is free for patients to use, and appearing in this directory is not an endorsement of any provider.

For the mechanism and evidence behind ketamine therapy, see the national treatment hub. For more on how listings work, read How to read a Regenerated city hub and Featured vs Verified vs organic.

A note on Texas's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

HB 1802 / Psilocybin and MDMA Research (2021)
Required Texas Health and Human Services Commission to study psilocybin and MDMA for PTSD treatment in veterans; report completed.
Texas Ibogaine Initiative (HB 3717, 2025 pending)
Would allocate $50 million for FDA-regulated ibogaine clinical trials, potentially the largest state psychedelic research investment in US history.
Texas Controlled Substances Act
Mirrors federal scheduling.

Texas enforces federal scheduling. The Texas Medical Board oversees prescriber conduct. DEA enforcement on ketamine clinics focuses on diversion and Ryan Haight Act telehealth rules. Texas PMP requires controlled substance reporting. Texas has seen rapid ketamine clinic growth in Austin, Dallas, and Houston markets with corresponding enforcement attention on compounding and telehealth practices.

Ketamine Therapy in San Antonio, answered.

Ketamine therapy generally refers to a monitored infusion or, less commonly, a nasal formulation given to adults whose depression has not responded well to standard treatment. In San Antonio this is usually administered in a medical office or infusion suite with clinical staff present throughout. It is considered alongside, not instead of, an existing treatment plan, and a provider should explain how it fits with your current care before starting.

Adults with depression or related conditions that have not improved sufficiently with other treatment are often considered after a full psychiatric and medical assessment. Pregnancy, uncontrolled blood pressure, significant heart disease, or active psychosis commonly lead a San Antonio provider to recommend waiting or pursuing a different approach. Your full medication list and substance use history should be part of that conversation. Bipolar disorder calls for particular caution, since ketamine and esketamine can sometimes unsettle mood in ways a provider needs to monitor closely or decide to avoid altogether.

Cost depends on the setting, the staffing involved, and whether assessment, monitoring, medication, and follow up are billed together or separately, so this page does not publish a figure that could mislead you. Intravenous ketamine for depression is usually cash pay, while nasal esketamine or evaluation visits may have partial insurance coverage depending on your plan. Ask for an itemized written quote and confirm coverage with your insurer directly.

Short term effects can include dissociation, nausea, changes in blood pressure, or drowsiness during and shortly after an infusion, which is why monitoring and a recovery period are standard. Longer term risks depend on frequency of use and individual health history. A San Antonio provider should walk through these risks in writing before your first session and explain how they are monitored and managed during treatment.

Dosing is set by the prescriber based on your diagnosis, body weight, medical history, and how you respond during monitored sessions, not from a fixed schedule applied to every patient. A course typically starts with an initial series followed by a clinical review of your response before any further sessions are planned. Ask how your provider measures improvement and what would change the plan. That clinical dosing is not the same as unsupervised microdosing, which a monitored San Antonio practice would not offer outside a structured, supervised protocol.

Ketamine is a legal prescription medication when administered by a licensed clinician for an appropriate medical reason, though intravenous use for depression is off-label, meaning it is prescribed outside its original FDA approval. Confirm that the prescriber holds an active Texas medical license in good standing, which you can verify through the Texas Medical Board's public license lookup, and ask who supervises the infusion itself.

This page focuses on who actually treats patients in San Antonio and how to evaluate them, while the national hub covers the mechanism and evidence that apply everywhere. Unlike an open web search, organic order here is not sold, Featured placements are labeled and capped, and Verified reflects credential checks rather than how much a provider spends, so the ordering itself carries different information than a typical search results page.

Some research has looked at ketamine for substance use alongside standard addiction treatment, but evidence remains limited and it is not an approved or standalone treatment for addiction. Most established use and evidence relates to depression that has not responded to other care. A San Antonio provider should be clear about what is and is not supported by current research before recommending treatment for this purpose.

11 Best Ketamine Therapy Clinics in San Antonio, Texas

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

What does this directory page list?

Ketamine Therapy clinics in San Antonio

11 Clinics

Phoenix Mental Health- Ketamine, TMS, and ECT Treatment

Neuro Sports Performance and Rehab

Cantera Psychiatry

Insight Mental Wellness

Revitalize Wellness Clinic

IV Therapy & Wellness

Heading Health Ketamine Center

Meraki Holistic Counseling

Klarisana

Transcend Health Solutions

Tree of Life Counseling Center - Alyssa Cedillo LPC-S, RPT-S

A note on Texas's ketamine therapy rules.

Ketamine Therapy in San Antonio, answered.

Ketamine Therapy in nearby Cities

Other Treatments available in San Antonio

11 Best Ketamine Therapy Clinics in San Antonio, Texas

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

What does this directory page list?

Ketamine Therapy clinics in San Antonio

11 Clinics

A note on Texas's ketamine therapy rules.

Ketamine Therapy in San Antonio, answered.

What is ketamine therapy and how is it typically used for depression in San Antonio?

Who is generally considered a good candidate for ketamine therapy, and who is usually told to wait?

How much does ketamine therapy cost in San Antonio, and is it covered by insurance?

What are the side effects and risks of ketamine therapy?

How are ketamine doses determined and how is a course of treatment usually structured?

Is ketamine therapy legal, and what credentials should a San Antonio provider have?

How does this San Antonio page differ from the national ketamine therapy hub or a general web search?

Does ketamine therapy help with addiction, and what does current evidence support?

Ketamine Therapy in nearby Cities

Other Treatments available in San Antonio