At a Glance Low dose naltrexone (LDN) uses 1.5 to 4.5 mg nightly, far below the 50 mg dose used for addiction treatment, to modulate the immune system rather than block opioid receptors. Jill Smith’s 2011 pilot RCT at Penn State showed 88% clinical response and 33% remission in pediatric Crohn’s using 0.1 mg/kg LDN….
A practical guide to eating with mast cell activation syndrome, covering high-histamine foods, histamine liberators, DAO inhibitors, safe food lists, and strategies for meal planning and reintroduction.
Low dose naltrexone (LDN) uses tiny doses of an opioid-blocking drug to boost endorphins, reduce inflammation, and modulate the immune system. Here is what the research says about its benefits, proper dosing, and which conditions respond best.
Most labs flag vitamin D as “normal” at 30 ng/mL, but the research on immune function, bone density, and disease prevention points to a much higher target. Here’s how to get there safely.
Heavy metal detox that is supported by evidence means medical chelation after blood or urine testing confirms a raised metal level. Foot baths, zeolite and detox drops do not remove metals from tissue.
Colon hydrotherapy, or colonic irrigation, runs warm filtered water into the colon through a rectal tube over 45 to 60 minutes. Its best supported use is bowel prep before colonoscopy; constipation relief is promising, and detox claims are not supported.
Low dose naltrexone (LDN) is gaining traction as an adjunct therapy for autoimmune diseases including Hashimoto’s, MS, Crohn’s, and rheumatoid arthritis. Here is a condition-by-condition look at the evidence, how it works, and how to bring it up with your doctor.
A practical guide to dietary strategies during Lyme disease treatment, covering anti-inflammatory foods, foods to avoid, and supplements that support healing.
The fibromyalgia diet with the most research behind it is an anti-inflammatory, Mediterranean-style pattern built on vegetables, fish, olive oil and nuts. Gluten, dairy and additives like MSG are worth testing one at a time, because the studies on them are small and mixed.
The best-supported menopause diet is a Mediterranean-style pattern with about 1,200 mg of calcium and 1.0 to 1.2 g of protein per kg daily, plus fewer hot flash triggers such as alcohol, sugar, caffeine and spicy food.
To get rid of brain fog, find and treat its cause first, such as sleep apnea, thyroid disease, low B12, iron or vitamin D, blood sugar swings or medication side effects. Then sleep, exercise and diet carry the strongest evidence, ahead of supplements and advanced therapies.
The generic “take fish oil” advice misses the point. EPA and DHA do different things, dose matters enormously, and most people aren’t taking nearly enough to get clinical results.