Fisetin is a strawberry flavonoid that cleared senescent cells and extended lifespan in aged mice. Human evidence is early: Mayo Clinic's AFFIRM trials are testing a two-day high dose, and no human dose is validated.
An honest evidence review of urolithin A, the gut-microbiome mitophagy activator. What the randomized human trials show for muscle strength and mitochondrial health, the 500 to 1,000 mg doses used, safety, and what remains unproven.
Glutathione is the main antioxidant your cells make, built from cysteine, glycine and glutamic acid. A 2015 randomized trial found 1,000 mg a day of oral glutathione raised body stores by 30 to 35 percent; here is how NAC, liposomal, IV and nebulized forms compare.
Magnesium glycinate, citrate, and threonate are absorbed differently and act on different tissues, so the form you choose determines which symptoms it actually helps.
Most labs flag vitamin D as “normal” at 30 ng/mL, but the research on immune function, bone density, and disease prevention points to a much higher target. Here’s how to get there safely.
The generic “take fish oil” advice misses the point. EPA and DHA do different things, dose matters enormously, and most people aren’t taking nearly enough to get clinical results.
