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4 Best Stem Cell Therapy Clinics in Fresno, California

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

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Fresno, CA

Stem Cell Therapy clinics in Fresno

Fresno supports a regenerative medicine market shaped by both private clinics and regional academic medicine. Local referral networks run through Community Regional Medical Center and Saint Agnes, and stem cell practice in the area spans north Fresno, Fig Garden, and the Clovis border. Patient demand splits across three buckets: orthopedic injections for active adults and aging athletes, neurological and autoimmune protocols marketed to longevity-focused patients, and IV-based allogeneic products offered by private wellness clinics. The FDA classifies most stem cell injections for orthopedic, neurological, or longevity use as investigational biologics under 21 CFR Part 1271, meaning they require either a Biologics License or an active Investigational New Drug authorization. Autologous bone marrow and adipose products may qualify as Section 361 when minimally manipulated and used for homologous function. SB 1004 (2017) requires written disclosure when stem cell therapy is not FDA-approved. The Medical Board of California regulates physician practice under Business and Professions Code 651. Proposition 71 (2004) established the California Institute for Regenerative Medicine (CIRM). The FDA secured a 2022 permanent injunction against the California Stem Cell Treatment Center over non-compliant adipose SVF products. The 4 Fresno clinics listed below have been reviewed against our vetting criteria, including federal NPI lookup, OIG exclusion screening, and California Medical Board licensure checks.

4 Clinics

Innovative Medical Center

Fresno, CA

Innovative Medical Center, in Fresno, offers regenerative medicine and integrative-therapy protocols centered on oxygen-based and cell-based treatments. The clinic provides Ozone Therapy, including 1…

  • PRP Therapy
  • Ozone Therapy
  • Arthritis Treatment
  • Chelation Therapy
  • Migraine Treatment
MD on staff

I Vie Infusions

Fresno, CA

I Vie Infusions, an IV therapy clinic in Fresno, California, offers a comprehensive range of intravenous nutrient protocols and custom IV cocktails designed for symptom support and physiologic optimi…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • IV Therapy
 MD on staff

Campise Chiropractic

Fresno, CA

Campise Chiropractic Fresno, a functional and integrative medicine clinic in Fresno, offers chiropractic care alongside regenerative and supportive modalities including stem-cell therapy, acupuncture…

  • Hyperbaric Oxygen Therapy (HBOT)
  • Arthritis Treatment
  • Chelation Therapy
  • Red Light Therapy
  • Stem Cell Therapy

Bautista Health & Anti-Aging

Fresno, CA

Bautista Health & Anti-Aging, a hormone and peptide optimization clinic in Fresno, specializes in testosterone replacement therapy and hormone replacement therapy alongside regenerative orthobiologic…

  • PRP Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Cryotherapy
  • Erectile Dysfunction (ED) Treatment
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Regulatory context

A note on California's stem cell therapy rules.

California cellular therapy providers are subject to 21 CFR Part 1271. Minimally manipulated human cells, tissues, and cellular and tissue-based products used for homologous use are regulated under Section 361 without premarket approval. Products that are more than minimally manipulated, used non-homologously, or combined with a drug or device are regulated as biologics under Section 351 and require an IND for clinical use or a BLA for marketing. Adipose-derived stromal vascular fraction, culture-expanded mesenchymal stem cells, and exosomes used for orthopedic, cosmetic, neurologic, and longevity indications are generally Section 351 products.

  • California Senate Bill 1004 (2017, Health and Safety Code Section 1644.5)
    Requires providers of non-FDA-approved stem cell therapies to post a notice to patients disclosing that the treatment has not been approved by the FDA.
  • California Proposition 71 (2004) and Proposition 14 (2020), California Institute for Regenerative Medicine
    Established and refunded CIRM to fund regenerative medicine research under strict scientific and ethical oversight.
  • California Business and Professions Code Section 651
    Prohibits false, misleading, or deceptive medical advertising, regularly cited in disciplinary actions against stem cell marketing.
  • California Business and Professions Code Section 2052 (Medical Practice Act)
    Governs physician licensure and prohibits unlicensed practice of medicine, including unauthorized administration of biologic injections.

California has been a focal point of federal enforcement. In United States v California Stem Cell Treatment Center (2022), the Ninth Circuit upheld FDA authority to regulate stromal vascular fraction as a Section 351 drug, resulting in a permanent injunction against the clinic. The FDA has issued multiple warning letters to California providers marketing stem cell and exosome therapies. The Medical Board of California has disciplined physicians for false advertising under BPC 651 and for administering unapproved biologics. The California Department of Public Health enforces tissue bank licensing. Class-action consumer suits against regenerative clinics have produced settlements.

Sources: fda.gov · leginfo.legislature.ca.gov · mbc.ca.gov · cirm.ca.gov

Stem Cell Therapy in Fresno, answered.

Most stem cell therapies at private Fresno clinics are not FDA-approved. The FDA has approved certain hematopoietic stem cell products for blood and immune disorders, but stem cell injections for orthopedic, neurological, or longevity use are generally investigational. They require a Biologics License or an active Investigational New Drug authorization, or they must qualify as Section 361 minimally manipulated and homologous-use products under 21 CFR Part 1271. SB 1004 (2017) requires written disclosure when stem cell therapy is not FDA-approved.

Fresno sits in the premium metro tier. Single-joint autologous bone marrow or adipose injections typically run $5,000 to $15,000 per session. Systemic IV protocols using allogeneic umbilical cord or Wharton's jelly products range $10,000 to $25,000, and full multi-session protocols can reach $20,000 to $50,000. Exosome add-ons range $4,000 to $8,000. Insurance rarely covers these treatments because the FDA classifies most protocols as investigational.

Autologous stem cells come from your own body, usually harvested from bone marrow aspirate or adipose tissue and reinjected the same day. When minimally manipulated and used for homologous function, they often fall under FDA Section 361, which does not require pre-market approval. Allogeneic stem cells come from a donor source, most commonly umbilical cord blood or Wharton's jelly, and are generally classified as Section 351 biologics that require an active Investigational New Drug authorization. Fresno clinic offerings span both categories, so ask which classification applies before treatment.

Yes. Research programs at Community Regional Medical Center and Saint Agnes periodically run FDA-authorized stem cell trials across orthopedics, neurology, cardiology, and oncology. Search clinicaltrials.gov and filter by Fresno or the broader metro to see active recruiting studies. Trial participation is typically low-cost or free compared to commercial protocols and includes structured follow-up with imaging and lab monitoring.

Verify physician licensure through the California Medical Board and confirm the clinic's NPI number through the NPPES registry. Check the FDA warning letter database for the clinic name and the HHS Office of Inspector General exclusion list. Ask whether the treatment is Section 361 or Section 351, whether the clinic operates under an Investigational New Drug authorization for allogeneic or expanded products, and whether adverse events are tracked. Ask specifically about compliance with SB 1004.

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