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40 Best Ketamine Therapy Clinics in Los Angeles, California

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

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Los Angeles, CA

Ketamine Therapy clinics in Los Angeles

Los Angeles has multiple clinics offering ketamine therapy, a fast growing segment for treatment resistant depression, PTSD, chronic pain, and anxiety. California is a leading market for IV ketamine clinics and compounded lozenge telehealth, with strong oversight by the Medical Board of California. Most Los Angeles clinics deliver IV ketamine infusions in a monitored clinical setting, typically across a 6 session induction protocol, followed by maintenance infusions. Spravato (esketamine), the FDA approved nasal spray for treatment resistant depression, is available in Los Angeles only at REMS certified clinics and is often covered by insurance when medical necessity is documented. Compounded ketamine lozenges and troches are also prescribed in Los Angeles, sometimes through telehealth platforms like Mindbloom, Joyous, and Innerwell, subject to Ryan Haight Act and DEA special registration considerations. Local pricing in Los Angeles sits in the standard range: single IV infusions run 500 to 900 dollars, a full 6 session protocol lands at 3,000 to 5,400, and Spravato copays depend on insurance coverage. A reputable Los Angeles ketamine clinic will pair pharmacology with integration support, monitor vitals during infusion, and have a clear crisis and follow up plan.

40 Clinics, showing page 1 of 3

Center for Healthy Sex

Los Angeles, CA

Center for Healthy Sex, a mental-health clinic in Los Angeles, specializes in sex therapy and sex-addiction treatment using ketamine-assisted psychotherapy protocols. The clinic offers ketamine thera…

  • Ketamine Therapy
  • Erectile Dysfunction (ED) Treatment
MD on staff

Trauma Outpatient Center

Los Angeles, CA

Trauma Outpatient Center in Los Angeles offers ketamine therapy for adults and adolescents, alongside outpatient mental health services for individuals, couples, and families. The clinic focuses on t…

  • Ketamine Therapy
MD on staff

Caire Health

Los Angeles, CA

Caire Health, a ketamine-therapy clinic in Los Angeles, offers ketamine treatment for depression and anxiety when conventional pharmaceutical and talk-therapy approaches have proved insufficient. The…

  • Ketamine Therapy

New U Therapy

Los Angeles, CA

New U Therapy, a mental health clinic in Los Angeles, specializes in ketamine therapy for treatment-resistant depression, anxiety, and related conditions. The practice serves children, adolescents, a…

  • Ketamine Therapy
MD on staff

Wave Psychiatric Group

Los Angeles, CA

Wave Psychiatric Group, a ketamine-therapy clinic in Los Angeles, offers ketamine-assisted psychotherapy and psychedelic-assisted therapy for patients with treatment-resistant depression, anxiety, PT…

  • Ketamine Therapy
  • Psychedelic Therapy
MD on staff

Pala Medicine Ketamine Therapy

Los Angeles, CA

Pala Medicine Ketamine Therapy, located in Los Angeles, offers ketamine infusions and ketamine-assisted psychotherapy (KAP) for treatment-resistant depression, anxiety, obsessive-compulsive disorder,…

  • Ketamine Therapy
  • Psychedelic Therapy
MD on staff

Innerwell Ketamine Therapy - West Hollywood

Los Angeles, CA

Innerwell Ketamine Therapy, a ketamine-assisted psychotherapy clinic in Los Angeles, provides ketamine treatment for patients with treatment-resistant depression, anxiety, PTSD, and related condition…

  • Ketamine Therapy
MD on staff

Mental Health Center

Los Angeles, CA

Mental Health Center, a ketamine-therapy clinic in Los Angeles, offers ketamine infusion and Spravato (esketamine nasal spray) for treatment-resistant depression, anxiety, and PTSD. The practice focu…

  • Ketamine Therapy

Los Angeles PTSD Therapy Collective

Los Angeles, CA

Los Angeles PTSD Therapy Collective, located in Los Angeles, specializes in hormone replacement therapy and ED treatment as part of an integrated approach to mental-health care. The clinic offers bot…

  • Ketamine Therapy
  • Erectile Dysfunction (ED) Treatment
  • Hormone Replacement Therapy (HRT)
MD on staff

Psychiatry And Counseling

Los Angeles, CA

Psychiatry and Counseling Los Angeles, in Los Angeles, offers ketamine therapy for treatment-resistant depression, anxiety, and related mood disorders. The clinic provides outpatient ketamine treatme…

  • Ketamine Therapy
MD on staff

Goldberg Psychiatry

Los Angeles, CA

Goldberg Psychiatry, a ketamine-therapy clinic in Los Angeles, specializes in treatment-resistant depression, anxiety, and post-traumatic stress disorder using ketamine-assisted protocols alongside t…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
MD on staff

Bespoke Treatment

Los Angeles, CA

Bespoke Treatment, a ketamine-therapy clinic in Los Angeles, offers esketamine (Spravato) and IV ketamine infusions for treatment-resistant depression, anxiety, and PTSD, alongside transcranial magne…

  • Transcranial Magnetic Stimulation (TMS)
  • Neurofeedback Therapy
  • Ketamine Therapy
MD on staff

New U Therapy Center & Family Services

Los Angeles, CA

New U Therapy Center & Family Services, located in Los Angeles, offers Ketamine Therapy alongside comprehensive outpatient mental-health services for children, adolescents, adults, seniors, couples, …

  • Ketamine Therapy
MD on staff

Felicity Mental Health Ketamine Therapy - Century City

Los Angeles, CA

Felicity Mental Health Ketamine Therapy, located in Century City, Los Angeles, specializes in ketamine-assisted psychotherapy for treatment-resistant depression, anxiety, and PTSD. The clinic offers …

  • Ketamine Therapy
  • Psychedelic Therapy
MD on staff

Westwood Minds Psychiatry & TMS

Los Angeles, CA

Westwood Minds Psychiatry & TMS, located in Los Angeles, offers Transcranial Magnetic Stimulation (TMS) therapy for treatment-resistant depression and related mood conditions. The clinic provides Neu…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy

Regulatory context

A note on California's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • SB 803 (2023, vetoed) and SB 1012 (2024, stalled)
    Proposed regulated therapeutic access to psilocybin, MDMA, mescaline, and DMT; Governor Newsom vetoed SB 58 (2023) citing lack of treatment guidelines.
  • Local decriminalization resolutions
    Oakland (2019), Santa Cruz (2020), Arcata, San Francisco, and Berkeley have passed non-binding resolutions deprioritizing enforcement of natural psychedelics; no legal therapeutic framework.

California enforces federal DEA scheduling. The Medical Board of California investigates prescriber misconduct, including ketamine diversion and inadequate patient monitoring. Several high-profile California ketamine-related deaths (including Matthew Perry's 2023 overdose) have intensified board scrutiny of clinic practices. DEA enforcement targets compounding, diversion, and Ryan Haight Act telehealth compliance.

Ketamine Therapy in Los Angeles, answered.

In Los Angeles, a single IV ketamine infusion typically runs 500 to 900 dollars, with a full 6 session induction protocol at 3,000 to 5,400. Premium clinics on the higher end, more affordable providers on the lower end. Intramuscular ketamine often costs less, around 250 to 500 per session. Compounded ketamine lozenges via telehealth run 250 to 500 per month. Spravato (esketamine) is frequently covered by insurance for treatment resistant depression; out of pocket list price is roughly 600 to 900 per treatment session, with most patients paying a copay.

Ketamine is a Schedule III controlled substance and has been FDA approved as an anesthetic since 1970. Spravato (esketamine), a derivative nasal spray, is FDA approved for treatment resistant depression under a REMS program requiring in clinic administration and post dose monitoring. IV, intramuscular, and compounded oral ketamine for depression, PTSD, and chronic pain are used off label with Emerging to Strong evidence depending on indication. Off label prescribing is legal for DEA registered providers but must follow state and federal controlled substance rules.

Los Angeles ketamine is delivered by MDs and DOs (typically psychiatrists, anesthesiologists, emergency medicine, or pain specialists) holding a DEA registration and California controlled substance authority. Nurse practitioners and physician assistants may prescribe or administer depending on California scope of practice and supervisory rules. Spravato requires a REMS certified clinic and certified prescriber. Verify the provider's DEA registration, board certification, and whether a monitoring clinician is present during infusions.

Yes, with caveats. Mindbloom, Joyous, Innerwell, and similar platforms prescribe compounded ketamine lozenges to California residents through telehealth, subject to the Ryan Haight Act and DEA special registration rules currently in effect. These programs pair at home dosing with virtual integration support and cost roughly 250 to 500 per month. In clinic IV and intramuscular ketamine remain the standard for treatment resistant depression and PTSD and cannot be delivered via telehealth. Spravato always requires in clinic REMS administration.

Verify DEA registration on the DEA Office of Diversion Control registrant lookup and California medical board license status. Confirm board certification in psychiatry, anesthesiology, emergency medicine, or pain medicine. Ask about the monitoring protocol during infusion (vitals, continuous clinician presence), integration therapy options, and the clinic's crisis and safety plan. Check whether the clinic is Spravato REMS certified if that is your treatment path. Be cautious of providers who skip screening, push large prepaid packages, or offer take home IV ketamine.

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