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14 Best Ozone Therapy Clinics in Los Angeles, California

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

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Los Angeles, CA

Ozone Therapy clinics in Los Angeles

Ozone Therapy in Los Angeles, CA

intro

Los Angeles, California has a visible integrative and functional medicine scene, and clinics in the area advertise ozone therapy as part of their services. Ozone is a three-oxygen molecule that practitioners deliver through several delivery methods, including major autohemotherapy (MAH), minor autohemotherapy (MinorAH), prolozone joint injections, rectal or vaginal insufflation, ozonated saline, and higher-dose protocols such as 10-pass ozone. The proposed mechanism is oxidative hormesis, a brief and controlled oxidative challenge that is theorised to upregulate endogenous antioxidant defences, modulate immune signalling pathways, and improve tissue oxygen utilisation at the mitochondrial level. It is critical to be clear with patients up front: ozone therapy is NOT FDA-approved for any medical use. The FDA issued a formal declaration in 1976 stating that ozone is a toxic gas with no known useful medical application, and that position has not been revised in the decades since. Clinics listed here offer ozone under physician clinical judgement, not under an approved indication, so patients should evaluate evidence quality, informed consent language, and provider credentials carefully before booking a session or committing to a package.

14 Clinics

MD on staff

AMA Regenerative Medicine & Skincare

Los Angeles, CA

AMA Regenerative Medicine & Skincare, a functional and integrative medicine clinic in Los Angeles, specializes in regenerative modalities including stem-cell therapy, hyperbaric oxygen therapy, and o…

  • Ozone Therapy
  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy
MD on staff

Advanced BioCell

Los Angeles, CA

Advanced BioCell, a regenerative-medicine clinic in Los Angeles, offers stem-cell therapy and allogeneic cell therapy alongside prolozone and ozone-therapy protocols. The clinic specializes in longev…

  • Ozone Therapy
  • Arthritis Treatment
  • Lyme Disease Treatment
  • Red Light Therapy
  • Peptide Therapy
MD on staff

Nenergy Boost

Los Angeles, CA

Nenergy Boost, in Brentwood, California, specializes in IV nutrient therapy and bioidentical hormone replacement therapy for longevity and age-related decline. The clinic offers Myers Cocktail infusi…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
MD on staff

Dr. Padra Nourparvar Stem Cell & PRP Institute of L.A.

Los Angeles, CA

Dr. Padra Nourparvar Stem Cell & PRP Institute of L.A., located in Los Angeles, offers a comprehensive regenerative-medicine program centered on cell-based therapies and orthobiologics. The clinic pr…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • Shockwave Therapy
MD on staff

Bio-identical Hormone Replacement Therapy & Weight Loss

Los Angeles, CA

Bio-identical Hormone Replacement Therapy & Weight Loss, located in Los Angeles, specializes in hormone optimization and regenerative medicine across a broad spectrum of modalities. The clinic offers…

  • PRP Therapy
  • Ozone Therapy
  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Hyperbaric Oxygen Therapy (HBOT)
MD on staff

Dental Wellness Arts Holistic Dentist

Los Angeles, CA

Dental Wellness Arts Holistic Dentist, a regenerative dentistry practice in Los Angeles, offers biological dentistry alongside ozone-supported procedures and laser therapy for select dental and oral-…

  • Ozone Therapy
  • Laser Therapy (LLLT)
  • Sleep Apnea Treatment
  • TMJ Treatment

Center For Holistic Dentistry

Los Angeles, CA

Center for Holistic Dentistry, a regenerative-dentistry practice in Los Angeles, specializes in holistic dental care with an emphasis on biocompatible materials and minimally-invasive treatment appro…

  • Ozone Therapy
  • Laser Therapy (LLLT)
MD on staff

Global Hyperbaric Oxygen Therapy

Los Angeles, CA

Global Hyperbaric Oxygen Therapy Los Angeles, a regenerative-medicine clinic in Los Angeles, offers hyperbaric oxygen therapy (HBOT) alongside a comprehensive range of cellular and supportive therapi…

  • PRP Therapy
  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy
MD on staff

Angel Longevity

Los Angeles, CA

Dr. Anju Mathur, MD, a functional medicine doctor in North Hollywood, California, focuses on identifying and addressing the root causes of health conditions rather than managing symptoms alone. The p…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • Ozone Therapy
  • IV Therapy

Rejuvenate Wellness & Health Center

Los Angeles, CA

Rejuvenate Wellness & Health Center in Los Angeles specializes in hormone replacement therapy and testosterone replacement therapy alongside peptide protocols, IV therapy, and regenerative orthobiolo…

  • PRP Therapy
  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Peptide Therapy

Acupuncture + Ozone + Neurofeedback at Body Mind Revolution

Los Angeles, CA

Body Mind Revolution, an integrative practice in Los Angeles, combines acupuncture, Neurofeedback Therapy, and Ozone Therapy alongside functional-medicine evaluation. The clinic addresses chronic pai…

  • Ozone Therapy
  • Neurofeedback Therapy
MD on staff

Angel Longevity Medical Center

Los Angeles, CA

Angel Longevity Medical Center, a functional medicine clinic in Los Angeles, specializes in hormone replacement therapy, cell-based therapies, and regenerative medicine. The practice offers bioidenti…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • Ozone Therapy
  • IV Therapy

Rachel West DO - Integrative Family Practice

Los Angeles, CA

Rachel West DO, an integrative family practice in Los Angeles, specializes in functional-medicine workups and individualized treatment planning that draws on evidence-based approaches across conventi…

  • Vitamin IV Therapy
  • Ozone Therapy
  • IV Therapy
  • Chelation Therapy
  • Hormone Replacement Therapy (HRT)

Studio Dental Arts

Los Angeles, CA

Studio Dental Arts, a biological dentistry practice in Studio City, specializes in regenerative dental procedures incorporating ozone therapy, laser dentistry, and red-light therapy alongside biocomp…

  • Ozone Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
  • Red Light Therapy
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Regulatory context

A note on California's ozone therapy rules.

The "other" category is a catchall for regenerative wellness modalities with inconsistent federal oversight. Red light therapy devices (photobiomodulation) have narrow FDA 510(k) clearances for acne, muscle pain, and wound healing, not systemic regeneration. Whole-body cryotherapy is NOT FDA-approved for any medical indication and received an FDA safety communication in July 2016 warning of asphyxiation, frostbite, and burn risks. Ozone therapy is NOT FDA-approved for any medical use and the FDA has stated ozone is a toxic gas with no known useful medical application. Condition-specific regenerative offerings (hair restoration with minoxidil or finasteride, ED care beyond PDE5 inhibitors and shockwave) have varying approval depending on route and drug source.

  • California Medical Practice Act (Bus. & Prof. Code §§ 2000-2529)
    Defines medical practice and corporate practice of medicine prohibitions strictly enforced against lay-owned medical spas.
  • California Business & Professions Code §§ 2051-2052
    Prohibits unlicensed practice of medicine and aiding and abetting by non-physician owners.
  • Board of Registered Nursing Standardized Procedures (CCR Title 16 § 1474)
    Requires physician-developed standardized procedures for RNs performing cosmetic and wellness injections or laser work.

California is among the strictest enforcement states. The Medical Board of California has issued public advisories and taken disciplinary action against medical spas for corporate practice of medicine violations, unsupervised RN injections, and false advertising of unapproved therapies. Ozone therapy is heavily scrutinized and clinics making cancer or infection treatment claims risk board discipline and Attorney General consumer protection action. The California Department of Public Health and local health departments also investigate facility and infection control issues at wellness clinics.

Ozone Therapy in Los Angeles, answered.

No. Ozone therapy is NOT FDA-approved for any medical use. The FDA issued a 1976 declaration stating ozone is a toxic gas with no known useful medical application, and that position has not changed. Clinics that offer ozone do so under physician clinical judgement, not under an approved indication. Many marketing claims for ozone are unsupported by high-quality clinical evidence, so any informed decision about booking a session should start with that clear disclosure.

Pricing in Los Angeles typically runs $200 to $400 per session for standard major autohemotherapy (MAH), with prolozone joint injections, insufflation, and MinorAH often priced similarly or slightly lower. Higher-dose 10-pass ozone is considerably more expensive, usually $600 to $900 per session, with packages of six to ten sessions priced substantially higher. Package pricing can lower the per-session rate but raises total spend. Remember that ozone is NOT FDA-approved, is not covered by insurance, and out-of-pocket cost is the norm.

Integrative practitioners commonly claim benefits for immune support, chronic infections such as Lyme disease and herpes, systemic inflammation, chronic fatigue, autoimmune conditions, and musculoskeletal pain using prolozone for joints and discs. The quality of clinical evidence supporting these claims is low, studies are often small or uncontrolled, and ozone therapy is NOT FDA-approved for any of these indications. Treat strong claims with caution.

In California, ozone therapy is most commonly delivered by MDs and DOs practising integrative or functional medicine, because naturopathic scope is either limited or unlicensed. Chiropractors generally cannot administer intravenous ozone, and scope varies by state medical and naturopathic board positions. Regardless of license type, verify active state licensure before any appointment, and remember that ozone therapy is NOT FDA-approved and is offered under physician clinical judgement rather than any approved indication.

Verify that the lead clinician holds an active state license, ask for written informed consent that clearly states ozone is NOT FDA-approved, and look for realistic evidence framing rather than cure claims. Avoid clinics that promise to cure cancer, autoimmune disease, or chronic infection. Membership in groups such as the AAOT is a peer-community signal, not an FDA credential, and should never substitute for verifying licensure and reading consent forms.

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