260 Best Psychedelic Therapy Clinics in the US

This is the national page for psychedelic therapy on Regenerated.com, listing clinics across the United States that record the treatment. Psychedelic therapy, also called psychedelic assisted therapy or psychedelic assisted psychotherapy, pairs a supervised dose of a psychedelic compound with preparation and integration sessions led by a trained facilitator or licensed therapist. The compounds people ask about are psilocybin, the active ingredient in so called magic mushrooms, MDMA, LSD and ketamine, which is the only one a US clinician can legally prescribe today. Psychiatrists, psychiatric nurse practitioners, psychologists, licensed therapists and, in state programs, licensed facilitators deliver it. Patients often compare it with ketamine therapy, transcranial magnetic stimulation (TMS), electroconvulsive therapy (ECT), standard antidepressants and trauma focused talk therapy.

The evidence picture is promising and still unsettled. No classic psychedelic is FDA approved for any medical use, and psilocybin, MDMA and LSD remain Schedule I controlled substances under federal law. Research led by Roland Griffiths at the Johns Hopkins Center for Psychedelic and Consciousness Research, along with trials at New York University and Imperial College London, found meaningful short term improvement in depression, distress linked to serious illness and some addictions, and the FDA has granted psilocybin breakthrough therapy designation for treatment resistant depression. The FDA declined to approve MDMA assisted therapy for PTSD after reviewing trial data, citing concerns about study design. Ketamine is FDA approved as an anesthetic and used off label for depression, while esketamine nasal spray is approved for treatment resistant depression.

Candidates are generally adults with depression, PTSD, end of life distress or a substance use disorder that has not responded to standard care, who can attend preparation and integration sessions. People with a personal or family history of psychosis or bipolar disorder, uncontrolled heart disease or high blood pressure, pregnancy, or certain medications such as lithium are usually told to wait or look elsewhere. Anyone in crisis should contact their own clinician first, since psychedelic programs are not emergency services.

Supply looks different from most treatments on this site. Ketamine assisted psychotherapy is offered in psychiatry practices, infusion clinics and mental health groups in most states. Legal psilocybin sessions for adults happen through state licensed service centers in Oregon and licensed healing centers in Colorado, while university hospitals across the country run clinical trials that accept screened volunteers. Listings concentrate in Oregon, Colorado, California, Texas, Florida and New York, and many patients travel to a state program or trial site rather than wait for options at home.

Before booking anywhere, ask who leads the session, what license they hold, and whether a medical clinician screens you and is available during the dose. Ask exactly what is administered: the compound, its legal basis in that state, the route and its source, whether it is a lab tested product or a compounded one. Ask for written disclosure of risks, including anxiety, frightening experiences, raised blood pressure and heart rate, and rare psychiatric reactions. Ask what a quote itemizes across screening, preparation, the dosing session and integration, and what follow up looks like afterward.

This national list is not for sale. Organic order is never paid ranking, Featured slots are labeled and capped, and Verified means the clinic completed credential checks, not that it spent money. Regenerated.com is free for patients, and inclusion in the directory is not an endorsement. Open the state hubs below the list to build a shortlist near you, and remember that what is legal depends on the state.

For mechanism, legal status and terms in more depth, read the psychedelic therapy guide. Two short explainers cover how listings work: How to read a Regenerated city hub and Featured vs Verified vs organic.