Velara Wellness
- Transcranial Magnetic Stimulation (TMS)
- Ketamine Therapy
- Psychedelic Therapy
Read the Psychedelic Therapy guide for the educational context behind this treatment category.
San Diego, CA
Search for psychedelic assisted therapy in San Diego, CA and most of what you find are licensed medical and mental health clinics offering ketamine assisted psychotherapy, the form available here through a prescriber rather than a research trial. In this metro, "psychedelic assisted therapy" almost always means ketamine delivered under medical supervision and paired with talk therapy, not psilocybin, MDMA, or other compounds still confined to research settings. Clinics cluster in a few recognizable parts of the metro: the Hillcrest medical corridor, integrative and wellness-oriented practices around La Jolla and UTC along I-5 and I-805, and a smaller set of offices through North County in Encinitas and Carlsbad along the 101 and I-5. Mission Valley sits roughly between these clusters, and some patients reach it from East County along I-8.
A typical first visit happens in a physician office or a dedicated infusion suite, and usually includes a medical and psychiatric screening, a conversation about goals and contraindications, and a plan for how many sessions might be appropriate. Sessions are supervised, and most practices pair the medication with structured talk therapy before and after. Follow up typically involves integration sessions to process what came up, though the cadence varies by clinic and patient. Ketamine is FDA approved as an anesthetic, and its use for depression or anxiety is off label, so most of this care is cash pay. This page focuses on choosing among San Diego providers; the national psychedelic therapy hub covers how the treatment works and what the evidence shows.
Before booking anywhere, ask who supervises the session and their license and specific training in this work, what substance is used and how it is sourced and dosed, how side effects and risks are disclosed in writing, what happens if the approach does not help, and which costs are bundled into a quoted fee versus billed separately.
The order clinics appear in below is not paid placement, and a labeled Featured slot is capped so it cannot crowd out the rest of the list. A Verified badge means a clinic's credentials have been checked, not that it paid for visibility, and using this directory costs patients nothing. Being listed here is not an endorsement of any clinic. Read How to read a Regenerated city hub and Featured vs Verified vs organic before comparing listings.
Regulatory context
Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.
California enforces federal DEA scheduling. The Medical Board of California investigates prescriber misconduct, including ketamine diversion and inadequate patient monitoring. Several high-profile California ketamine-related deaths (including Matthew Perry's 2023 overdose) have intensified board scrutiny of clinic practices. DEA enforcement targets compounding, diversion, and Ryan Haight Act telehealth compliance.
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Psychedelic Therapy clinics across the US