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3 Best Psychedelic Therapy Clinics in San Diego, California

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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What does this directory page list?

This page lists directory records associated with Psychedelic Therapy in the San Diego, California browsing area. A browsing area can include nearby municipalities. Confirm each clinic's street address and current services directly.

Matching records:
3. Source: the current directory result set, including pages beyond this screen.
Treatment filter:
Psychedelic Therapy.
Source limits:
Listing information is not an independent clinic evaluation. Record updates do not establish field-level check dates.

Read the Psychedelic Therapy guide for the educational context behind this treatment category.

San Diego, CA

Psychedelic Therapy clinics in San Diego

Search for psychedelic assisted therapy in San Diego, CA and most of what you find are licensed medical and mental health clinics offering ketamine assisted psychotherapy, the form available here through a prescriber rather than a research trial. In this metro, "psychedelic assisted therapy" almost always means ketamine delivered under medical supervision and paired with talk therapy, not psilocybin, MDMA, or other compounds still confined to research settings. Clinics cluster in a few recognizable parts of the metro: the Hillcrest medical corridor, integrative and wellness-oriented practices around La Jolla and UTC along I-5 and I-805, and a smaller set of offices through North County in Encinitas and Carlsbad along the 101 and I-5. Mission Valley sits roughly between these clusters, and some patients reach it from East County along I-8.

A typical first visit happens in a physician office or a dedicated infusion suite, and usually includes a medical and psychiatric screening, a conversation about goals and contraindications, and a plan for how many sessions might be appropriate. Sessions are supervised, and most practices pair the medication with structured talk therapy before and after. Follow up typically involves integration sessions to process what came up, though the cadence varies by clinic and patient. Ketamine is FDA approved as an anesthetic, and its use for depression or anxiety is off label, so most of this care is cash pay. This page focuses on choosing among San Diego providers; the national psychedelic therapy hub covers how the treatment works and what the evidence shows.

Before booking anywhere, ask who supervises the session and their license and specific training in this work, what substance is used and how it is sourced and dosed, how side effects and risks are disclosed in writing, what happens if the approach does not help, and which costs are bundled into a quoted fee versus billed separately.

The order clinics appear in below is not paid placement, and a labeled Featured slot is capped so it cannot crowd out the rest of the list. A Verified badge means a clinic's credentials have been checked, not that it paid for visibility, and using this directory costs patients nothing. Being listed here is not an endorsement of any clinic. Read How to read a Regenerated city hub and Featured vs Verified vs organic before comparing listings.

3 Clinics

Velara Wellness
(23)
Physician status unknown

Velara Wellness

San Diego, CA

Velara Wellness, a ketamine and psychedelic-assisted therapy clinic in San Diego, offers Ketamine Infusion Therapy, Spravato (intranasal esketamine), and Transcranial Magnetic Stimulation for treatme…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Psychedelic Therapy
Daydream MD
(65)
Physician reported in record

Daydream MD

San Diego, CA

Daydream MD, a ketamine and psychedelic-assisted therapy clinic in San Diego, specializes in ketamine infusion and Spravato treatment for treatment-resistant depression and anxiety, alongside psyched…

  • IV Therapy
  • Ketamine Therapy
  • Psychedelic Therapy
  • Peptide Therapy
  • NAD IV Therapy
Center for Natural Anxiety Relief
(78)
Physician reported in record

Center for Natural Anxiety Relief

San Diego, CA

Center for Natural Anxiety Relief, in San Diego, combines neurofeedback and brain-mapping protocols with IV nutrient and NAD+ therapies to address anxiety, ADHD, autism spectrum disorder, and PTSD ac…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • Neurofeedback Therapy
  • IV Hydration
results per page

Regulatory context

A note on California's psychedelic therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • SB 803 (2023, vetoed) and SB 1012 (2024, stalled)
    Proposed regulated therapeutic access to psilocybin, MDMA, mescaline, and DMT; Governor Newsom vetoed SB 58 (2023) citing lack of treatment guidelines.
  • Local decriminalization resolutions
    Oakland (2019), Santa Cruz (2020), Arcata, San Francisco, and Berkeley have passed non-binding resolutions deprioritizing enforcement of natural psychedelics; no legal therapeutic framework.

California enforces federal DEA scheduling. The Medical Board of California investigates prescriber misconduct, including ketamine diversion and inadequate patient monitoring. Several high-profile California ketamine-related deaths (including Matthew Perry's 2023 overdose) have intensified board scrutiny of clinic practices. DEA enforcement targets compounding, diversion, and Ryan Haight Act telehealth compliance.

Psychedelic Therapy in San Diego, answered.

In most San Diego clinics it means ketamine assisted psychotherapy delivered under medical supervision, combined with talk therapy before and after the session. The setting is typically a physician office or infusion suite, not a retreat or studio, and the clinician or a partnered therapist helps structure what happens afterward.

Costs vary by clinic, by the credentials involved, and by how much therapy is bundled into the visit, so this page does not publish averages or session counts as fact. Much of this care is billed as cash pay, and insurance coverage for the therapy portion in particular is inconsistent, so ask for a written quote that itemizes what is and is not included.

Candidacy for psychedelic therapy in San Diego typically depends on a medical and psychiatric history review, since certain cardiovascular conditions, pregnancy, or a history of psychosis are commonly treated as reasons to wait or look elsewhere. A thorough intake screening by a licensed clinician, not a questionnaire alone, is what should determine this before any session is scheduled.

San Diego clinics offering psychedelic therapy generally start with an intake and screening visit, move into one or more supervised sessions, and follow with integration sessions to talk through the experience. The exact number of sessions and the spacing between them depends on the individual plan a clinician sets, which is why this page avoids stating a fixed course of treatment.

Look for a licensed physician, psychiatrist, or nurse practitioner directly involved in prescribing and supervising, plus a therapist with specific training in psychedelic integration if talk therapy is part of the plan. California license status for physicians and therapists can be checked through the Medical Board of California or the Board of Behavioral Sciences before booking.

A general search mixes advertising, directories, and unrelated results with no consistent standard behind what appears first. This page lists clinics against a single set of criteria, labels any Featured placement, marks Verified credential checks separately from paid visibility, and does not accept payment for organic ranking order.

Organic order on this page is not for sale and does not reflect payment. A Featured label marks a capped number of paid placements so they cannot dominate the page, and Verified indicates a clinic's credentials were checked rather than that it paid for a badge. All three are shown separately so you can tell which is which.

Evidence for ketamine assisted psychotherapy in treatment-resistant depression and some other conditions is more developed than for most other psychedelic compounds, which remain largely confined to clinical trials rather than everyday prescribing. Ask any clinic you consider what the research specifically supports for your situation and what remains unproven, rather than taking a general claim at face value.

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