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20 Best Ketamine Therapy Clinics in Indiana

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Read the Ketamine Therapy guide: evidence, costs and questions to ask

What does this directory page list?

This page lists directory records associated with Ketamine Therapy in Indiana. A browsing area can include nearby municipalities. Confirm each clinic's street address and current services directly.

Matching records:
20. Source: the current directory result set, including pages beyond this screen.
Treatment filter:
Ketamine Therapy.
Source limits:
Listing information is not an independent clinic evaluation. Record updates do not establish field-level check dates.

Read the Ketamine Therapy guide for the educational context behind this treatment category.

Indiana

Ketamine Therapy clinics in Indiana

Ketamine therapy clinics in Indiana are concentrated in and around Indianapolis, with additional locations in the surrounding suburbs. Fort Wayne, Evansville and South Bend also have treatment options, giving patients in the northeastern, southwestern and northern parts of the state regional alternatives to driving to the capital. Rural stretches of the state, including much of southern and western Indiana, have limited or no local access, and patients there should expect a drive of an hour or more. Some residents near the Ohio, Kentucky or Illinois borders may find it practical to compare options across state lines, though this page covers Indiana listings only.

Indiana has no ketamine specific statute; it relies on the general federal and professional rules that already govern prescribing and administering controlled substances, so the main question is who is licensed to prescribe, administer and supervise it. A physician or physician assistant typically orders and oversees treatment, while a nurse may administer it under that supervision, consistent with Indiana's scope of practice rules. Treatment is usually delivered in a physician's office or a dedicated infusion suite rather than a spa style setting.

You can check a prescriber's standing through the Indiana Professional Licensing Agency, which administers the Medical Licensing Board of Indiana for physicians and physician assistants. Nurses can be verified through the Indiana State Board of Nursing. A clean license record confirms someone is currently authorized to practice in Indiana and shows any public disciplinary history; it does not tell you how much ketamine experience that person has or predict an outcome.

Before booking anywhere in Indiana, ask who evaluates you, who is physically present during treatment, and what credential that person holds. Ask exactly what is being administered, intravenous ketamine, nasal esketamine or a compounded nasal formulation, and where it comes from. Ask how risks and side effects are disclosed in writing, what the plan is if treatment does not help, and request a quote that itemizes evaluation, medication, monitoring and follow-up.

Listing order on this page is not paid ranking. Featured slots are labeled and capped, and a Verified label reflects credential checks rather than how much a clinic paid. Regenerated.com is free for patients to use, and appearing in this directory is not an endorsement of any clinic. The national ketamine therapy hub covers the mechanism and the evidence. Read How to read a Regenerated city hub and Featured vs Verified vs organic.

20 Clinics, showing page 1 of 2

Axon Health Associates
(20)
Physician status unknown

Axon Health Associates

Indianapolis, IN

Axon Health Associates, an outpatient mental health practice in Indianapolis, specializes in ketamine-assisted therapy for treatment-resistant depression, anxiety, and post-traumatic stress disorder.…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Integrated Health Solutions
Physician status unknown

Integrated Health Solutions

Indianapolis, IN

Integrated Health Solutions, an IV therapy clinic in Indianapolis, offers a comprehensive menu of custom intravenous protocols designed to support recovery, immune function, energy, and metabolic hea…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • Biofeedback Therapy
  • IV Therapy
  • IV Hydration
NuLife Behavioral Health
(64)
Physician status unknown

NuLife Behavioral Health

Fishers, IN

NuLife Behavioral Health, located in Fishers, Indiana, offers ketamine therapy and detoxification services for patients addressing substance-use disorders alongside concurrent mental-health condition…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Chelation Therapy
Vitality IV Bar
Physician status unknown

Vitality IV Bar

Indianapolis, IN

Vitality IV Bar, an IV therapy clinic in Indianapolis, offers comprehensive intravenous nutrient protocols including Myers Cocktails, NAD+ infusions, high-dose vitamin C, and electrolyte rehydration.…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • IV Hydration
  • Ketamine Therapy
Kentuckiana Ketamine Institute
(5)
Physician reported in record

Kentuckiana Ketamine Institute

Watson, IN

Kentuckiana Ketamine Institute, a ketamine-therapy clinic in Louisville, offers ketamine infusion for treatment-resistant depression, bipolar disorder, PTSD, migraine, and complex regional pain syndr…

  • PRP Therapy
  • Multiple Sclerosis (MS) Treatment
  • Ketamine Therapy
  • Arthritis Treatment
  • Chelation Therapy
AlphaOmega Wellness
(95)
Physician status unknown

AlphaOmega Wellness

Greenwood, IN

AlphaOmega Wellness, a ketamine-therapy clinic in Greenwood, Indiana, offers IV Ketamine Therapy for treatment-resistant depression, anxiety, and related mood conditions. The clinic positions ketamin…

  • Ketamine Therapy
  • Hormone Replacement Therapy (HRT)
T Zone Men's Testosterone Clinic
(2)
Physician status unknown

T Zone Men's Testosterone Clinic

Winfield, IN

T Zone Men's Testosterone Clinic, an integrative-medicine practice in Crown Point, specializes in hormone replacement therapy and testosterone optimization for men, supported by comprehensive lab-bas…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
Prime IV Hydration & Wellness
Physician status unknown

Prime IV Hydration & Wellness

Greenwood, IN

Prime IV Hydration & Wellness, an IV therapy clinic in Greenwood, offers comprehensive IV nutrient therapy and peptide protocols alongside bioidentical hormone replacement and hormone pellet implanta…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • IV Hydration
  • Hyperbaric Oxygen Therapy (HBOT)
Indy Behavioral Health
Physician status unknown

Indy Behavioral Health

Indianapolis, IN

Indy Behavioral Health, an integrative clinic in Indianapolis, offers ketamine therapy and esketamine (Spravato) alongside transcranial magnetic stimulation for treatment-resistant depression, anxiet…

  • Ozone Therapy
  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Hyperbaric Oxygen Therapy (HBOT)
  • Ketamine Therapy
Indianapolis TMS
(7)
Physician reported in record

Indianapolis TMS

Fishers, IN

Indianapolis TMS, a neuromodulation clinic in Fishers, specializes in transcranial magnetic stimulation (TMS) and ketamine-assisted therapy for treatment-resistant depression and related mood disorde…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Klarity
(26)
Physician reported in record

Klarity

Greenwood, IN

Klarity, a mental health clinic in Greenwood, Indiana, specializes in Ketamine Therapy and psychedelic-assisted protocols for treatment-resistant depression, anxiety, and post-traumatic stress. The c…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Hormone Replacement Therapy (HRT)
(26)
Physician status unknown

The Anxiety Center

Fishers, IN

The Anxiety Center, a ketamine-therapy clinic in Fishers, Indiana, specializes in ketamine infusion treatment for treatment-resistant anxiety, depression, and related mood conditions. The practice of…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Hormone Replacement Therapy (HRT)
RegenMed
(22)
Physician reported in record

RegenMed

Watson, IN

Dr. Rafael F Cruz, MD, a regenerative medicine practice in Jeffersonville, focuses on integrative treatment of traumatic brain injury, stroke, and nerve trauma. The clinic addresses mental-health pre…

  • Vitamin IV Therapy
  • PRP Therapy
  • IV Therapy
  • Multiple Sclerosis (MS) Treatment
  • Ketamine Therapy
Evansville Ketamine & Vitamin Center
(100)
Physician status unknown

Evansville Ketamine & Vitamin Center

Evansville, IN

Evansville Ketamine & Vitamin Center, in Evansville, Indiana, offers Ketamine Therapy for treatment-resistant depression, anxiety, and migraine, alongside IV Therapy and B12 injections. The clinic po…

  • Vitamin IV Therapy
  • IV Therapy
  • Ketamine Therapy
  • Migraine Treatment
Indiana Ketamine
(165)
Physician status unknown

Indiana Ketamine

Fishers, IN

Indiana Ketamine, a Ketamine Therapy Clinic in Fishers, offers ketamine-assisted psychotherapy for patients experiencing treatment-resistant depression, anxiety, trauma, and post-traumatic stress. Th…

  • Ketamine Therapy
results per page

Regulatory context

A note on Indiana's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • SB 139 / Psilocybin Research (2024)
    Authorized clinical research on psilocybin for treatment-resistant mental health conditions at Indiana universities; no therapeutic access framework.
  • Indiana Controlled Substances Act
    Mirrors federal scheduling.

Indiana enforces federal scheduling. The Indiana Medical Licensing Board oversees prescriber conduct. DEA enforcement on ketamine clinics focuses on diversion and Ryan Haight Act telehealth rules. Indiana INSPECT PDMP requires controlled substance reporting.

Ketamine Therapy in , answered.

Ketamine therapy describes giving ketamine, usually by IV infusion, nasal spray, or a compounded nasal formulation, to treat certain mental health conditions. In Indiana, treatment is typically delivered in a physician's office or infusion suite under the supervision of a physician or physician assistant. Esketamine, the nasal form with FDA approval for depression, is distinct from off label IV ketamine, and a clinic should be clear about which one it offers.

Most Indiana clinics offering ketamine therapy are located in or near Indianapolis, with additional options in Fort Wayne, Evansville and South Bend. Patients outside these metros, including much of rural southern and western Indiana, generally need to travel to reach a clinic. This statewide listing shows where current options are, but call ahead to confirm formulation, scheduling and whether a location is accepting new evaluations.

Cost depends on the formulation used, how much monitoring and staffing a session requires, and whether psychotherapy is bundled in. IV ketamine for depression is usually billed as cash pay, while esketamine may be covered by insurance when a plan's specific criteria are met. Ask any clinic for a written quote that separates evaluation, medication, monitoring and follow-up, since this page does not publish average prices.

Indiana does not have a law written specifically for ketamine; it relies on the general federal and professional rules that already govern prescribing and administering controlled substances. In practice this means a physician or physician assistant typically orders and supervises treatment, while a nurse may administer it under that oversight, following Indiana's standard scope of practice rules for medical and nursing licenses.

Physicians and physician assistants can be verified through the Indiana Professional Licensing Agency, which administers the Medical Licensing Board of Indiana, and nurses can be checked through the Indiana State Board of Nursing. Both let you confirm a license is active and review public disciplinary history. Neither one tells you how experienced a provider is with ketamine specifically, so ask about that directly.

Ketamine therapy is generally considered for adults with treatment resistant depression or certain other conditions who have already tried standard options without enough relief. People with uncontrolled high blood pressure, certain heart conditions, active substance misuse, or psychosis are often told to wait or seek a different approach after evaluation. A proper screening by a qualified provider, not a brief phone call, is what should decide this.

Ketamine therapy is most studied for treatment resistant depression, and esketamine has approval for that specific use. Use for anxiety, PTSD, bipolar depression and addiction is explored in smaller studies and off label practice, and the evidence for lasting benefit in those areas is still limited. Ask any Indiana provider what the proposed use is based on and how improvement will be measured.

This page covers ketamine therapy clinics across Indiana rather than one city, so it works for comparing regions before narrowing to a specific metro's city page or the national ketamine therapy hub for background on the treatment itself. Unlike a general search, Regenerated.com does not sell organic order, labels and caps Featured slots, and uses Verified to mean credential checks rather than ad spend.

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