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Clinics in San Francisco, California

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

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San Francisco, CA

Arthritis Treatment clinics in San Francisco

San Francisco is a Bay Area market that blends UCSF-affiliated specialists with a thoughtful integrative medicine scene across the city and the Peninsula. Patients dealing with osteoarthritis, inflammatory arthritis, or post-injury joint degeneration can access both traditional pathways and newer biologic options without leaving the area.

On the regenerative side, clinics commonly offer platelet-rich plasma injections, bone marrow aspirate concentrate, and prolotherapy for mild to moderate osteoarthritis. Evidence for these is best described as Emerging for knee and hip osteoarthritis and Insufficient for most other joints. For inflammatory arthritis such as rheumatoid or psoriatic disease, conventional biologics remain the standard of care with Strong evidence, and regenerative injections are typically considered adjunctive rather than primary.

The clinics listed below have been reviewed for basic credentialing and transparency. Confirm physician specialty and evidence discussion before any injection series.

29 Clinics, showing page 2 of 2

TLC Medicine

San Francisco, CA

TLC Medicine, a functional and integrative medicine clinic in San Francisco, offers acupuncture, ozone therapy, and integrative-medicine workups for patients with chronic pain and autoimmune conditio…

  • Ozone Therapy
  • Multiple Sclerosis (MS) Treatment
  • Arthritis Treatment
  • Psoriasis Treatment
MD on staff

California Regenerative Clinic

San Francisco, CA

California Regenerative Clinic, a regenerative medicine practice in San Francisco, specializes in stem-cell therapy, peptide protocols, and hormone optimization alongside erectile-dysfunction treatme…

  • PRP Therapy
  • Shockwave Therapy
  • Arthritis Treatment
  • Peptide Therapy
  • Erectile Dysfunction (ED) Treatment

Healthwell Physical Therapy Group

San Francisco, CA

Healthwell Physical Therapy Group, a regenerative-medicine clinic in San Francisco, offers a comprehensive range of cell-based therapies, orthobiologics, and energy-based treatments. The clinic featu…

  • PRP Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)

Bay Area Foot Care

San Francisco, CA

Bay Area Foot Care, a regenerative podiatry practice in San Francisco, specializes in platelet-rich plasma therapy and stem-cell injections for foot and ankle conditions, alongside radial shockwave t…

  • PRP Therapy
  • Shockwave Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
  • Cryotherapy
MD on staff

Biotherapy Clinic

San Francisco, CA

Biotherapy Clinic, in San Francisco, offers colon hydrotherapy and ozone-based therapies alongside acupuncture and IV protocols for metabolic and immune support. The clinic specializes in digestive o…

  • Colon Hydrotherapy
  • Ozone Therapy
  • IV Therapy
  • Arthritis Treatment
  • Chelation Therapy
MD on staff

Biofeedbacksf

San Francisco, CA

Biofeedback SF, a neuromodulation clinic in San Francisco, specializes in neurofeedback and biofeedback protocols for migraine, arthritis, and asthma management. Neurofeedback uses real-time monitori…

  • Biofeedback Therapy
  • Neurofeedback Therapy
  • Arthritis Treatment
  • Migraine Treatment
  • Erectile Dysfunction (ED) Treatment

Gameday Men's Health Downtown San Francisco TRT & ED Clinic

San Francisco, CA

Gameday Men's Health, a testosterone replacement therapy and peptide-therapy clinic in downtown San Francisco, specializes in hormone optimization and erectile-dysfunction treatment for men. The prac…

  • PRP Therapy
  • Shockwave Therapy
  • IV Therapy
  • Arthritis Treatment
  • Peptide Therapy
MD on staff

Pacific Crest Orthopedics - IASM

San Francisco, CA

Pacific Crest Orthopedics - IASM, located in San Francisco, specializes in regenerative approaches to musculoskeletal pain and orthopedic injury. The clinic offers platelet-rich plasma therapy for jo…

  • PRP Therapy
  • Arthritis Treatment
MD on staff

Dr crissp

San Francisco, CA

Dr. Crissp, a regenerative medicine clinic in San Francisco, specializes in longevity-oriented care combining functional and integrative medicine with orthobiologic therapies. The practice offers pla…

  • PRP Therapy
  • Arthritis Treatment
  • Migraine Treatment
  • Stem Cell Therapy

Prolotherapy SF

San Francisco, CA

Prolotherapy SF, a regenerative medicine clinic in San Francisco, specializes in non-surgical orthobiologic treatments for musculoskeletal pain and sports injuries. The practice offers platelet-rich …

  • PRP Therapy
  • Arthritis Treatment
MD on staff

Avid Sports Medicine

San Francisco, CA

Avid Sports Medicine, a regenerative medicine clinic in San Francisco, specializes in stem-cell therapy, platelet-rich plasma injections, and shockwave therapy for sports injuries and musculoskeletal…

  • PRP Therapy
  • Shockwave Therapy
  • Ketamine Therapy
  • Arthritis Treatment
  • Stem Cell Therapy
MD on staff

Truspine

San Francisco, CA

Truspine, a musculoskeletal and pain clinic in San Francisco, offers acupuncture, dry needling, and shockwave therapy alongside red-light therapy for patients with chronic pain and soft-tissue condit…

  • Shockwave Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
  • Migraine Treatment
  • Red Light Therapy
MD on staff

Dr. Jacob Wardwell

San Francisco, CA

Dr. Jacob Wardwell's practice in San Francisco specializes in regenerative medicine and integrative care, offering platelet-rich plasma therapy, prolotherapy, and stem-cell procedures for musculoskel…

  • PRP Therapy
  • IV Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
  • Red Light Therapy
MD on staff

Ajith Malige, MD

San Francisco, CA

Ajith Malige, MD, an orthopaedic surgeon and sports medicine specialist in San Francisco, offers bone-marrow-aspirate therapy and platelet-rich plasma injections for musculoskeletal and joint conditi…

  • PRP Therapy
  • Arthritis Treatment
  • Stem Cell Therapy

Regulatory context

A note on California's arthritis treatment rules.

The "other" category is a catchall for regenerative wellness modalities with inconsistent federal oversight. Red light therapy devices (photobiomodulation) have narrow FDA 510(k) clearances for acne, muscle pain, and wound healing, not systemic regeneration. Whole-body cryotherapy is NOT FDA-approved for any medical indication and received an FDA safety communication in July 2016 warning of asphyxiation, frostbite, and burn risks. Ozone therapy is NOT FDA-approved for any medical use and the FDA has stated ozone is a toxic gas with no known useful medical application. Condition-specific regenerative offerings (hair restoration with minoxidil or finasteride, ED care beyond PDE5 inhibitors and shockwave) have varying approval depending on route and drug source.

  • California Medical Practice Act (Bus. & Prof. Code §§ 2000-2529)
    Defines medical practice and corporate practice of medicine prohibitions strictly enforced against lay-owned medical spas.
  • California Business & Professions Code §§ 2051-2052
    Prohibits unlicensed practice of medicine and aiding and abetting by non-physician owners.
  • Board of Registered Nursing Standardized Procedures (CCR Title 16 § 1474)
    Requires physician-developed standardized procedures for RNs performing cosmetic and wellness injections or laser work.

California is among the strictest enforcement states. The Medical Board of California has issued public advisories and taken disciplinary action against medical spas for corporate practice of medicine violations, unsupervised RN injections, and false advertising of unapproved therapies. Ozone therapy is heavily scrutinized and clinics making cancer or infection treatment claims risk board discipline and Attorney General consumer protection action. The California Department of Public Health and local health departments also investigate facility and infection control issues at wellness clinics.

Arthritis Treatment in San Francisco, answered.

Knee and hip osteoarthritis have the most supportive data for platelet-rich plasma and bone marrow aspirate concentrate, though evidence is still considered Emerging rather than Strong. Thumb basal joint and shoulder osteoarthritis have smaller case series. Inflammatory arthritis such as rheumatoid disease requires systemic immunomodulation first, with regenerative injections used only as a local adjunct in specific joints after disease activity is controlled.

In most cases, no. Platelet-rich plasma, bone marrow aspirate, and adipose-derived procedures for arthritis are generally classified as investigational by commercial insurers and Medicare. Some diagnostic imaging, office visits, and conventional injections like corticosteroids or hyaluronic acid may still be covered. Ask each clinic for a written cost estimate and confirm what portion is cash-pay before scheduling.

Ask whether the product is autologous, meaning drawn from your own body that day, and whether any amniotic or umbilical product is being marketed as live stem cells. The FDA has issued warnings about clinics selling such products under unapproved claims. Legitimate practices will walk you through sourcing, processing, and realistic expectations rather than promising cures.

A typical stepwise approach starts with weight management, structured physical therapy, topical or oral anti-inflammatories, and intra-articular corticosteroid or hyaluronic acid injections. For many patients, these control symptoms for years. Regenerative injections are generally considered when conventional measures fail or when the patient wants to delay surgery. Surgical consultation is appropriate for end-stage joint degeneration.

A small but growing subset of clinics employ board-certified rheumatologists or physiatrists alongside regenerative protocols, giving patients one team for diagnosis and injection care. Most of the listings in this directory focus on one side or the other. The listings note scope of practice so patients can choose between a pure regenerative clinic, a rheumatology practice, or a combined model.

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