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151 Best Ketamine Therapy Clinics in Texas

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Read the Ketamine Therapy guide: evidence, costs and questions to ask

Texas

Ketamine Therapy clinics in Texas

Ketamine therapy in Texas is concentrated in the state's major metro areas. Houston, Dallas-Fort Worth, Austin, and San Antonio carry most of the supply, with clinics offering intravenous ketamine infusions, and in some cases esketamine nasal spray delivered under a different protocol. Patients in West Texas, the Panhandle, the Rio Grande Valley, and other areas far from these metros typically have far fewer options nearby and often plan for several hours of travel, an overnight stay, or multiple visits scheduled close together to reduce trips.

Someone searching for how to address chronic pain with ketamine should know that most of the established evidence for ketamine therapy concerns treatment-resistant depression, not pain. Ketamine infusion for chronic pain conditions is used in some Texas clinics, but it is an off-label application with thinner evidence, and results vary by condition and by patient. A page like this cannot tell you which clinic suits a chronic pain case: it can tell you how to read the list and what to ask before you commit.

In Texas, ketamine is a controlled substance, and administering it is generally limited to licensed physicians, physician assistants, and nurse practitioners working under physician oversight, usually in a medical office or a dedicated infusion suite rather than a spa-style setting. Scope of practice rules determine who can order and supervise treatment, so ask directly who is responsible for your care.

Before booking, check a prescriber or supervising physician through the Texas Medical Board, and check nurses through the Texas Board of Nursing. These boards confirm licensing status and public disciplinary history, not clinical skill with ketamine specifically. Ask about credentials and supervision, exactly what medication is used and where it comes from, how risks are disclosed in writing, what happens if treatment does not help, and what an itemized quote covers.

This list's organic order is not for sale. Featured placements are labeled and capped, and a Verified label reflects completed credential checks rather than advertising spend. Regenerated.com is free for patients to use, and appearing in this directory is not an endorsement. The national hub covers how ketamine therapy works and what the evidence supports in more detail: visit it before narrowing to a Texas provider. For more on how to read this list, see How to read a Regenerated city hub and Featured vs Verified vs organic.

151 Clinics, showing page 10 of 11

Fountain Life
(9)
Physician reported in record

Fountain Life

Lewisville, TX

Fountain Life, a longevity and regenerative-medicine center in Dallas, offers comprehensive cell-based therapies including stem-cell injections, exosome treatments, and bone-marrow-derived concentrat…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • Shockwave Therapy
Collaborative Wellness Center
(4)
Physician status unknown

Collaborative Wellness Center

Colleyville, TX

Collaborative Wellness Center, in Colleyville, specializes in hormone replacement therapy and bioidentical hormone replacement therapy for men and women, alongside peptide protocols and ketamine infu…

  • IV Hydration
  • Ketamine Therapy
  • Peptide Therapy
  • Hormone Replacement Therapy (HRT)
Within Center
(74)
Physician reported in record

Within Center

Bee Cave, TX

Within Center, a Ketamine & Psychedelic-Assisted Therapy clinic in Austin, offers ketamine therapy and psychedelic therapy administered by licensed medical professionals within a guided clinical fram…

  • IV Therapy
  • Ketamine Therapy
  • Psychedelic Therapy
  • NAD IV Therapy
Greater Heights Holistic Psychiatry
(445)
Physician reported in record

Greater Heights Holistic Psychiatry

Houston, TX

Greater Heights Holistic Psychiatry, a neuromodulation clinic in Houston, specializes in Transcranial Magnetic Stimulation (TMS) for treatment-resistant depression and anxiety. TMS uses magnetic puls…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Radical Revive
Physician reported in record

Radical Revive

El Paso, TX

Radical Revive, a mental health clinic in El Paso, specializes in ketamine infusion therapy and transcranial magnetic stimulation for treatment-resistant depression, anxiety, and mood disorders. The …

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Preston Hollow Psychiatry Group
(52)
Physician reported in record

Preston Hollow Psychiatry Group

Addison, TX

Preston Hollow Psychiatry Group, serving the Dallas-Fort Worth area, specializes in intranasal ketamine therapy for treatment-resistant depression alongside hormone optimization protocols. The practi…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Erectile Dysfunction (ED) Treatment
  • Hormone Replacement Therapy (HRT)
  • Testosterone Replacement Therapy (TRT)
Donya Pain and Wellness Center
(80)
Physician reported in record

Donya Pain and Wellness Center

El Paso, TX

Donya Pain and Wellness Center, a regenerative medicine clinic in El Paso, specializes in ketamine infusion therapy and stem-cell treatment alongside conventional pain-management interventions. The c…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • Ketamine Therapy
  • Arthritis Treatment
Lone Star Infusion
(111)
Physician reported in record

Lone Star Infusion

Houston, TX

Lone Star Infusion, a ketamine-therapy clinic in Houston, specializes in ketamine infusion protocols for treatment-resistant depression, anxiety, and post-traumatic stress. The clinic offers ketamine…

  • Ketamine Therapy
Dr. Humera Chowdhary, Beautiful Minds Frisco - Psychiatry and TMS
(125)
Physician reported in record

Dr. Humera Chowdhary, Beautiful Minds Frisco - Psychiatry and TMS

Frisco, TX

Beautiful Minds Psychiatry in Frisco offers Transcranial Magnetic Stimulation (TMS) and ketamine-assisted treatment for depression, anxiety, and treatment-resistant mood conditions across the lifespa…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Texas Pain Intervention Clinic
(597)
Physician reported in record

Texas Pain Intervention Clinic

McKinney, TX

Texas Pain Intervention Clinic in McKinney offers regenerative orthobiologics and ketamine therapy for chronic musculoskeletal pain. The practice specializes in bone-marrow-concentrate injections and…

  • PRP Therapy
  • Ketamine Therapy
  • Arthritis Treatment
  • Migraine Treatment
  • TMJ Treatment
Laura Wiginton
Physician status unknown

Laura Wiginton

Houston, TX

Laura Wiginton, a mental-health clinic in Houston, specializes in ketamine-assisted psychotherapy for treatment-resistant depression, anxiety, and PTSD. The practice frames ketamine therapy within a …

  • Ketamine Therapy
Tree of Life Counseling Center - Alyssa Cedillo LPC-S, RPT-S
(4)
Physician status unknown

Tree of Life Counseling Center - Alyssa Cedillo LPC-S, RPT-S

San Antonio, TX

Tree of Life Counseling Center, based in San Antonio, offers ketamine therapy alongside psychotherapy for patients with treatment-resistant depression, anxiety, and PTSD. The practice specializes in …

  • Ketamine Therapy
NeuMed Modern Urgent Care + IV Therapy, Heights
(677)
Physician status unknown

NeuMed Modern Urgent Care + IV Therapy, Heights

Houston, TX

NeuMed Modern Urgent Care + IV Therapy, located in Houston Heights, offers comprehensive IV nutrient therapy alongside urgent-care services. The clinic specializes in custom IV cocktails designed for…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • IV Hydration
  • Ketamine Therapy
Pain and Spine Physicians
(292)
Physician reported in record

Pain and Spine Physicians

Grapevine, TX

Pain and Spine Physicians, a regenerative pain-management clinic in Southlake, Texas, specializes in advanced interventional approaches to chronic musculoskeletal and neuropathic pain. The practice o…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Arthritis Treatment
  • Migraine Treatment
(381)
Physician reported in record

Heading Health, Ketamine and TMS

Rollingwood, TX

Heading Health offers ketamine therapy and Spravato (esketamine nasal spray) alongside transcranial magnetic stimulation (TMS) for treatment-resistant depression, anxiety, and related conditions. The…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
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Regulatory context

A note on Texas's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • HB 1802 / Psilocybin and MDMA Research (2021)
    Required Texas Health and Human Services Commission to study psilocybin and MDMA for PTSD treatment in veterans; report completed.
  • Texas Ibogaine Initiative (HB 3717, 2025 pending)
    Would allocate $50 million for FDA-regulated ibogaine clinical trials, potentially the largest state psychedelic research investment in US history.
  • Texas Controlled Substances Act
    Mirrors federal scheduling.

Texas enforces federal scheduling. The Texas Medical Board oversees prescriber conduct. DEA enforcement on ketamine clinics focuses on diversion and Ryan Haight Act telehealth rules. Texas PMP requires controlled substance reporting. Texas has seen rapid ketamine clinic growth in Austin, Dallas, and Houston markets with corresponding enforcement attention on compounding and telehealth practices.

Ketamine Therapy in , answered.

Ketamine therapy uses low, carefully controlled doses of the anesthetic ketamine, given intravenously or as esketamine nasal spray, to treat depression that has not responded to standard antidepressants. In Texas, treatment is typically delivered in a physician office or infusion suite with monitoring during and after each session. It is not a stand-alone treatment, and most protocols pair it with ongoing psychiatric care and follow-up.

Intravenous ketamine therapy for depression and ketamine infusion for chronic pain use the same medication but different protocols, dosing schedules, and goals, and the evidence base is stronger for depression than for pain. In Texas, both are typically off-label uses decided case by case between you and a prescriber, with dosing set individually rather than by a fixed schedule. Ask any clinic which use they are treating and what evidence supports it for your situation.

Providers are concentrated in Houston, Dallas-Fort Worth, Austin, and San Antonio, with fewer options across rural Texas, the Panhandle, and the Rio Grande Valley. Someone outside these metros should expect to travel, plan around monitored recovery time after each session, and arrange a driver, since you typically cannot drive yourself home afterward. Calling ahead to confirm current availability and scheduling is worthwhile before committing to a trip.

Cost depends on the formulation, the clinical setting, and whether psychotherapy is bundled in, and this page does not publish averages because those costs vary widely across Texas clinics. Intravenous ketamine for depression is commonly cash pay, while esketamine nasal spray may have insurance coverage when specific plan criteria are met. Ask your insurer about authorization first, and request a written quote that itemizes evaluation, medication, monitoring, and follow-up separately.

Ketamine therapy is legal in Texas when administered by licensed professionals operating within their scope of practice; ketamine itself is a controlled substance, not an unregulated wellness product. Administration is generally limited to physicians, physician assistants, and nurse practitioners working under physician oversight, typically in a medical office or infusion suite. Confirm with the clinic who evaluates you, who is physically present during treatment, and who supervises the overall plan.

Physicians and physician assistants can be checked through the Texas Medical Board, and nurses through the Texas Board of Nursing; both publish license status and public disciplinary history online. A clean record confirms standing but does not confirm experience with ketamine specifically or predict how you will respond to treatment. Pair a license check with direct questions about the supervising clinician's training and how recovery and complications are handled.

Ketamine therapy is generally considered for adults with treatment-resistant depression who have tried standard antidepressants without lasting relief, and sometimes for related conditions like bipolar depression under psychiatric supervision; people with certain cardiovascular, psychiatric, or substance use histories are often told to wait or look elsewhere first. Short-term side effects can include dissociation, elevated blood pressure, and nausea during and shortly after a session, and evidence for easing substance use disorders remains limited.

This page gathers clinics across all of Texas rather than one city, so it is useful for comparing regions and deciding whether to travel, while a city page or the national ketamine therapy hub narrows to local detail or to mechanism and evidence. Unlike a general search, organic order here is not for sale, Featured slots are labeled and capped, and a Verified label reflects completed credential checks rather than ad spend.

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