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151 Best Ketamine Therapy Clinics in Texas

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Read the Ketamine Therapy guide: evidence, costs and questions to ask

Texas

Ketamine Therapy clinics in Texas

Ketamine therapy in Texas is concentrated in the state's major metro areas. Houston, Dallas-Fort Worth, Austin, and San Antonio carry most of the supply, with clinics offering intravenous ketamine infusions, and in some cases esketamine nasal spray delivered under a different protocol. Patients in West Texas, the Panhandle, the Rio Grande Valley, and other areas far from these metros typically have far fewer options nearby and often plan for several hours of travel, an overnight stay, or multiple visits scheduled close together to reduce trips.

Someone searching for how to address chronic pain with ketamine should know that most of the established evidence for ketamine therapy concerns treatment-resistant depression, not pain. Ketamine infusion for chronic pain conditions is used in some Texas clinics, but it is an off-label application with thinner evidence, and results vary by condition and by patient. A page like this cannot tell you which clinic suits a chronic pain case: it can tell you how to read the list and what to ask before you commit.

In Texas, ketamine is a controlled substance, and administering it is generally limited to licensed physicians, physician assistants, and nurse practitioners working under physician oversight, usually in a medical office or a dedicated infusion suite rather than a spa-style setting. Scope of practice rules determine who can order and supervise treatment, so ask directly who is responsible for your care.

Before booking, check a prescriber or supervising physician through the Texas Medical Board, and check nurses through the Texas Board of Nursing. These boards confirm licensing status and public disciplinary history, not clinical skill with ketamine specifically. Ask about credentials and supervision, exactly what medication is used and where it comes from, how risks are disclosed in writing, what happens if treatment does not help, and what an itemized quote covers.

This list's organic order is not for sale. Featured placements are labeled and capped, and a Verified label reflects completed credential checks rather than advertising spend. Regenerated.com is free for patients to use, and appearing in this directory is not an endorsement. The national hub covers how ketamine therapy works and what the evidence supports in more detail: visit it before narrowing to a Texas provider. For more on how to read this list, see How to read a Regenerated city hub and Featured vs Verified vs organic.

151 Clinics, showing page 9 of 11

Holistic Behavioral Health
(85)
Physician status unknown

Holistic Behavioral Health

The Woodlands, TX

Holistic Behavioral Health, a functional and integrative medicine clinic in The Woodlands, specializes in ketamine therapy alongside comprehensive psychiatric care for treatment-resistant depression,…

  • Ketamine Therapy
Renavera
(6)
Physician reported in record

Renavera

Austin, TX

Renavera, a ketamine-therapy clinic in Austin, specializes in ketamine infusions for treatment-resistant depression, anxiety, trauma, and related conditions. The practice offers individualized ketami…

  • IV Therapy
  • Ketamine Therapy
Ketamine Breakthrough
(4)
Physician status unknown

Ketamine Breakthrough

Grapevine, TX

Ketamine Breakthrough, a ketamine-therapy clinic in Southlake, specializes in ketamine infusions for patients with treatment-resistant depression, anxiety, and chronic pain. The clinic emphasizes ind…

  • Ketamine Therapy
Mindful Health Solutions - TMS - Spravato Treatment
(14)
Physician reported in record

Mindful Health Solutions - TMS - Spravato Treatment

Austin, TX

Mindful Health Solutions, a mental-health clinic in Austin, TX, specializes in ketamine therapy and transcranial magnetic stimulation (TMS) for treatment-resistant depression and related mood disorde…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Inner Self Behavioral Health
(8)
Physician status unknown

Inner Self Behavioral Health

Fort Worth, TX

Inner Self Behavioral Health, a ketamine and psychedelic-assisted therapy clinic in Fort Worth, specializes in treatment-resistant depression, anxiety, and post-traumatic stress disorder. The practic…

  • Ketamine Therapy
Transcend Health Solutions
Physician reported in record

Transcend Health Solutions

San Antonio, TX

Transcend Health Solutions, a ketamine-therapy clinic in San Antonio, offers IV ketamine infusion and psychedelic-assisted therapy for treatment-resistant depression, anxiety, PTSD, and chronic pain.…

  • Ketamine Therapy
  • Migraine Treatment
  • Psychedelic Therapy
Janet Varela Colletto MS, LPC
(4)
Physician reported in record

Janet Varela Colletto MS, LPC

Houston, TX

Janet Varela Colletto, MS, LPC, a counselor in Houston, specializes in ketamine-assisted psychotherapy for individuals, couples, and groups. The practice offers ketamine therapy integrated with psych…

  • Ketamine Therapy
  • Hormone Replacement Therapy (HRT)
Greater Austin Pain Center - Pain Doctor
(1430)
Physician reported in record

Greater Austin Pain Center - Pain Doctor

Austin, TX

Greater Austin Pain Center, a regenerative pain-management clinic in Austin, offers platelet-rich plasma therapy and ketamine treatment alongside regenerative-medicine protocols for chronic musculosk…

  • PRP Therapy
  • Ketamine Therapy
  • Arthritis Treatment
  • Migraine Treatment
Dallas Medical Detox- Gallus Medical Detox Center
Physician reported in record

Dallas Medical Detox- Gallus Medical Detox Center

Mansfield, TX

Gallus Medical Detox Center, operating as Dallas Medical Detox in Mansfield, offers inpatient medical detoxification alongside ketamine therapy and IV protocols including NAD+ infusions. The clinic's…

  • IV Therapy
  • Ketamine Therapy
  • NAD IV Therapy
Saunatherapies
(1)
Physician status unknown

Saunatherapies

Dallas, TX

Saunatherapies, a mental health clinic in Dallas, offers ketamine therapy and psychedelic-assisted therapy for treatment-resistant conditions including PTSD and trauma. The practice combines these re…

  • Ketamine Therapy
  • Psychedelic Therapy
Innova Recovery Center
Physician status unknown

Innova Recovery Center

Shavano Park, TX

Innova Recovery Center, a regenerative medicine and mental-health clinic in San Antonio, offers an extensive array of cell-based therapies, orthobiologics, and energy-medicine modalities alongside tr…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • Ozone Therapy
Deep Eddy Psychotherapy
(209)
Physician reported in record

Deep Eddy Psychotherapy

Austin, TX

Deep Eddy Psychotherapy, an Austin-based mental health clinic, offers Transcranial Magnetic Stimulation (TMS) and esketamine therapy (SPRAVATO) as primary neuromodulation treatments for depression, a…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Magnolia Functional Wellness
(154)
Physician reported in record

Magnolia Functional Wellness

Grapevine, TX

Magnolia Functional Wellness, a Functional Medicine Clinic in Southlake, specializes in hormone replacement therapy and testosterone replacement therapy for men and women, alongside peptide therapy, …

  • PRP Therapy
  • Shockwave Therapy
  • IV Therapy
  • IV Hydration
  • Acne Treatment
Wells Medicine
(184)
Physician status unknown

Wells Medicine

Piney Point, TX

Wells Medicine, an interventional mental-health clinic in Houston, specializes in ketamine-assisted therapy and psychedelic-assisted protocols for treatment-resistant depression, anxiety, OCD, and PT…

  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Stem Cell Therapy
All Points North
(20)
Physician reported in record

All Points North

Fort Worth, TX

All Points North, a mental health and addiction-treatment clinic in Fort Worth, combines neurostimulation and oxygen-support modalities with trauma-focused psychotherapy. The practice offers Transcra…

  • Transcranial Magnetic Stimulation (TMS)
  • Neurofeedback Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Ketamine Therapy
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Regulatory context

A note on Texas's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • HB 1802 / Psilocybin and MDMA Research (2021)
    Required Texas Health and Human Services Commission to study psilocybin and MDMA for PTSD treatment in veterans; report completed.
  • Texas Ibogaine Initiative (HB 3717, 2025 pending)
    Would allocate $50 million for FDA-regulated ibogaine clinical trials, potentially the largest state psychedelic research investment in US history.
  • Texas Controlled Substances Act
    Mirrors federal scheduling.

Texas enforces federal scheduling. The Texas Medical Board oversees prescriber conduct. DEA enforcement on ketamine clinics focuses on diversion and Ryan Haight Act telehealth rules. Texas PMP requires controlled substance reporting. Texas has seen rapid ketamine clinic growth in Austin, Dallas, and Houston markets with corresponding enforcement attention on compounding and telehealth practices.

Ketamine Therapy in , answered.

Ketamine therapy uses low, carefully controlled doses of the anesthetic ketamine, given intravenously or as esketamine nasal spray, to treat depression that has not responded to standard antidepressants. In Texas, treatment is typically delivered in a physician office or infusion suite with monitoring during and after each session. It is not a stand-alone treatment, and most protocols pair it with ongoing psychiatric care and follow-up.

Intravenous ketamine therapy for depression and ketamine infusion for chronic pain use the same medication but different protocols, dosing schedules, and goals, and the evidence base is stronger for depression than for pain. In Texas, both are typically off-label uses decided case by case between you and a prescriber, with dosing set individually rather than by a fixed schedule. Ask any clinic which use they are treating and what evidence supports it for your situation.

Providers are concentrated in Houston, Dallas-Fort Worth, Austin, and San Antonio, with fewer options across rural Texas, the Panhandle, and the Rio Grande Valley. Someone outside these metros should expect to travel, plan around monitored recovery time after each session, and arrange a driver, since you typically cannot drive yourself home afterward. Calling ahead to confirm current availability and scheduling is worthwhile before committing to a trip.

Cost depends on the formulation, the clinical setting, and whether psychotherapy is bundled in, and this page does not publish averages because those costs vary widely across Texas clinics. Intravenous ketamine for depression is commonly cash pay, while esketamine nasal spray may have insurance coverage when specific plan criteria are met. Ask your insurer about authorization first, and request a written quote that itemizes evaluation, medication, monitoring, and follow-up separately.

Ketamine therapy is legal in Texas when administered by licensed professionals operating within their scope of practice; ketamine itself is a controlled substance, not an unregulated wellness product. Administration is generally limited to physicians, physician assistants, and nurse practitioners working under physician oversight, typically in a medical office or infusion suite. Confirm with the clinic who evaluates you, who is physically present during treatment, and who supervises the overall plan.

Physicians and physician assistants can be checked through the Texas Medical Board, and nurses through the Texas Board of Nursing; both publish license status and public disciplinary history online. A clean record confirms standing but does not confirm experience with ketamine specifically or predict how you will respond to treatment. Pair a license check with direct questions about the supervising clinician's training and how recovery and complications are handled.

Ketamine therapy is generally considered for adults with treatment-resistant depression who have tried standard antidepressants without lasting relief, and sometimes for related conditions like bipolar depression under psychiatric supervision; people with certain cardiovascular, psychiatric, or substance use histories are often told to wait or look elsewhere first. Short-term side effects can include dissociation, elevated blood pressure, and nausea during and shortly after a session, and evidence for easing substance use disorders remains limited.

This page gathers clinics across all of Texas rather than one city, so it is useful for comparing regions and deciding whether to travel, while a city page or the national ketamine therapy hub narrows to local detail or to mechanism and evidence. Unlike a general search, organic order here is not for sale, Featured slots are labeled and capped, and a Verified label reflects completed credential checks rather than ad spend.

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