15 Best Ketamine Therapy Clinics in Seattle, Washington

Patients researching ketamine therapy in Seattle often start downtown, then find most providers sit elsewhere. The clearest cluster is First Hill, the hospital district locals call Pill Hill, where psychiatric and infusion practices often share a building with other medical specialists. Capitol Hill and South Lake Union, just north and west of First Hill, carry a smaller but growing number of mental health and infusion offices. On the Eastside, Bellevue and Kirkland host separate clinics reached by SR-520 or I-90, useful for patients commuting from the suburbs. I-5 connects these pockets, with a few additional offices near the University District and Northgate. Confirm the exact address before booking.

In Seattle, ketamine therapy is typically delivered in a monitored clinical setting, either a psychiatric office with an infusion suite or a dedicated infusion center, with a prescriber and staff present throughout the session and recovery. A first visit usually includes a psychiatric and medical history, a review of current medications, a blood pressure check, and a conversation about whether IV ketamine, nasal esketamine, or ketamine paired with psychotherapy fits your situation, since these are distinct services with different monitoring needs. Ketamine is FDA approved only as an anesthetic, so using it for depression is off label; esketamine has a separate approval for treatment-resistant depression, so ask which pathway a provider is offering. Follow-up care should be built around how you respond, not a fixed number of visits decided in advance.

Before booking, ask who prescribes and who stays in the room during the infusion, where the ketamine or esketamine comes from, and how side effects and risks are disclosed in writing. Ask what the plan is if treatment does not help, and request a quote that itemizes the evaluation, medication, monitoring, and any psychotherapy or follow-up sessions. The national ketamine therapy hub covers mechanism and evidence across conditions; this page focuses on choosing among Seattle options.

This list is not a paid ranking. Organic order reflects how the directory sorts clinics, not what anyone pays; Featured placements are labeled and capped so they cannot crowd out the rest of the list; and Verified means a clinic's credentials have been checked, not that it spent more. Regenerated.com is free for patients, and appearing here is not an endorsement.

For more on how to read this list, see How to read a Regenerated city hub and Featured vs Verified vs organic.