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29 Best Arthritis Treatment Clinics in Mesa, Arizona

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

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Mesa, AZ

Arthritis Treatment clinics in Mesa

Mesa is part of the greater Phoenix East Valley, with a strong Mayo Clinic Arizona presence and several independent regenerative clinics. Patients dealing with osteoarthritis, inflammatory arthritis, or post-injury joint degeneration can access both traditional pathways and newer biologic options without leaving the area.

On the regenerative side, clinics commonly offer platelet-rich plasma injections, bone marrow aspirate concentrate, and prolotherapy for mild to moderate osteoarthritis. Evidence for these is best described as Emerging for knee and hip osteoarthritis and Insufficient for most other joints. For inflammatory arthritis such as rheumatoid or psoriatic disease, conventional biologics remain the standard of care with Strong evidence, and regenerative injections are typically considered adjunctive rather than primary.

The clinics listed below have been reviewed for basic credentialing and transparency. Confirm physician specialty and evidence discussion before any injection series.

29 Clinics, showing page 1 of 2

North Mesa Performance Chiropractic

Mesa, AZ

North Mesa Performance Chiropractic, led by Kyle Koenke DC in Mesa, specializes in shockwave therapy and regenerative physical medicine for musculoskeletal and sports-related conditions. The clinic o…

  • Shockwave Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
  • Erectile Dysfunction (ED) Treatment
  • Hormone Replacement Therapy (HRT)
MD on staff

Dose Wellness

Mesa, AZ

Dose Wellness, a longevity clinic in Mesa, offers an integrative approach combining peptide therapy, bioidentical hormone replacement, platelet-rich plasma injections, and IV nutrient therapy alongsi…

  • Vitamin IV Therapy
  • PRP Therapy
  • IV Therapy
  • Arthritis Treatment
  • Peptide Therapy
MD on staff

Virtuous Health Centers

Mesa, AZ

Virtuous Health Centers, a pain-management clinic in Mesa, specializes in regenerative and interventional approaches to chronic musculoskeletal pain. The practice offers platelet-rich plasma therapy …

  • PRP Therapy
  • Arthritis Treatment
MD on staff

The Regenerative Joint

Mesa, AZ

The Regenerative Joint, a regenerative medicine clinic in Mesa, Arizona, offers orthobiologic and injection-based therapies for musculoskeletal pain and joint conditions. Treatment modalities include…

  • PRP Therapy
  • Arthritis Treatment
  • Peptide Therapy
  • Red Light Therapy
  • Hormone Replacement Therapy (HRT)

Better Life Infusions

Mesa, AZ

Better Life Infusions, an IV Therapy Clinic in Mesa, specializes in intravenous nutrient delivery and supportive-medicine protocols. The practice offers IV Hydration, IV Therapy, and NAD+ infusions a…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • Ozone Therapy
  • IV Therapy
  • IV Hydration
MD on staff

Premier Pain Management

Mesa, AZ

Premier Pain Management, a regenerative pain-management clinic in Mesa, Arizona, offers a combination of interventional procedures and regenerative modalities for chronic musculoskeletal pain and neu…

  • Shockwave Therapy
  • Laser Therapy (LLLT)
  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy
  • Arthritis Treatment

Cornerstone Wellness Center

Mesa, AZ

Cornerstone Wellness Center in Mesa offers shockwave therapy and dry needling alongside physical therapy and massage for musculoskeletal pain and sports injuries. The clinic provides clinical-nutriti…

  • Shockwave Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
MD on staff

Arcadia Foot and Ankle

Mesa, AZ

Arcadia Foot and Ankle, located in Mesa, specializes in shockwave therapy for foot, ankle, and heel pain. Shockwave therapy is a regenerative modality that uses acoustic waves to stimulate tissue rep…

  • Shockwave Therapy
  • Arthritis Treatment

Natural Health Acupuncture & Chiropractic

Mesa, AZ

Natural Health Acupuncture & Chiropractic, located in Mesa, Arizona, specializes in regenerative physical medicine with a focus on shockwave therapy and tissue-regeneration protocols. The clinic offe…

  • Vitamin IV Therapy
  • Shockwave Therapy
  • IV Hydration
  • Arthritis Treatment
  • Migraine Treatment
MD on staff

AimQre

Mesa, AZ

AimQre, an integrative-medicine clinic in Mesa, Arizona, specializes in regenerative physical medicine and growth-factor therapy. The practice focuses on addressing root causes of health conditions r…

  • Biofeedback Therapy
  • Shockwave Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
MD on staff

Pain Arizona (formerly Arizona Pain Treatment Centers)

Mesa, AZ

Pain Arizona, a regenerative physical-medicine clinic in Mesa, specializes in platelet-rich plasma and joint-injection therapies for chronic musculoskeletal pain and sports-related injuries. The clin…

  • PRP Therapy
  • Shockwave Therapy
  • Arthritis Treatment
MD on staff

Southwest Spine & Rehab Chiropractic

Mesa, AZ

Southwest Spine & Rehab Chiropractic, a regenerative-medicine clinic in Mesa, offers stem-cell therapy, platelet-rich plasma injections, and shockwave therapy for musculoskeletal and spinal condition…

  • PRP Therapy
  • Shockwave Therapy
  • IV Therapy
  • Arthritis Treatment
  • Stem Cell Therapy
MD on staff

Nevy Health

Mesa, AZ

Nevy Health, a regenerative physical medicine clinic in Mesa, specializes in shockwave therapy and orthobiologic injections including stem-cell and prolotherapy protocols for musculoskeletal and join…

  • PRP Therapy
  • Shockwave Therapy
  • IV Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
MD on staff

CRM Wellness (Back2Action Chiropractic & Rehab)

Mesa, AZ

CRM Wellness, a regenerative physical medicine clinic in Mesa, Arizona, combines stem-cell therapy and shockwave treatment with chiropractic care, spinal decompression, and physical therapy for patie…

  • Vitamin IV Therapy
  • Shockwave Therapy
  • IV Therapy
  • Arthritis Treatment
  • Cryotherapy

LightRenew

Mesa, AZ

LightRenew, a pain-management clinic in Mesa, Arizona, specializes in laser therapy and hyperbaric oxygen therapy for musculoskeletal and neuropathic pain conditions. The clinic uses low-level laser …

  • Laser Therapy (LLLT)
  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy
  • Arthritis Treatment

Regulatory context

A note on Arizona's arthritis treatment rules.

The "other" category is a catchall for regenerative wellness modalities with inconsistent federal oversight. Red light therapy devices (photobiomodulation) have narrow FDA 510(k) clearances for acne, muscle pain, and wound healing, not systemic regeneration. Whole-body cryotherapy is NOT FDA-approved for any medical indication and received an FDA safety communication in July 2016 warning of asphyxiation, frostbite, and burn risks. Ozone therapy is NOT FDA-approved for any medical use and the FDA has stated ozone is a toxic gas with no known useful medical application. Condition-specific regenerative offerings (hair restoration with minoxidil or finasteride, ED care beyond PDE5 inhibitors and shockwave) have varying approval depending on route and drug source.

  • Arizona Medical Practice Act (A.R.S. Title 32, Ch. 13)
    Defines practice of allopathic medicine and rules for delegation to medical assistants, nurses, and APRNs in wellness settings.
  • Arizona Homeopathic and Integrated Medicine Board (A.R.S. Title 32, Ch. 29)
    Arizona is one of few states licensing homeopathic physicians who may legally use alternative modalities including ozone and chelation.
  • Arizona Naturopathic Physicians Medical Board (A.R.S. Title 32, Ch. 14)
    Licenses naturopathic doctors with prescribing authority and broad scope including IV and ozone therapies.

Arizona has a uniquely permissive framework due to its homeopathic and naturopathic licensure boards. Ozone, chelation, and off-label regenerative therapies are more commonly offered here than in most states. Enforcement focuses on unlicensed practice, misleading advertising, and patient harm. The Attorney General pursues deceptive health claims under the Arizona Consumer Fraud Act. The Medical Board and Naturopathic Board each take complaints against licensees for scope violations or fraudulent marketing.

Arthritis Treatment in Mesa, answered.

Knee and hip osteoarthritis have the most supportive data for platelet-rich plasma and bone marrow aspirate concentrate, though evidence is still considered Emerging rather than Strong. Thumb basal joint and shoulder osteoarthritis have smaller case series. Inflammatory arthritis such as rheumatoid disease requires systemic immunomodulation first, with regenerative injections used only as a local adjunct in specific joints after disease activity is controlled.

In most cases, no. Platelet-rich plasma, bone marrow aspirate, and adipose-derived procedures for arthritis are generally classified as investigational by commercial insurers and Medicare. Some diagnostic imaging, office visits, and conventional injections like corticosteroids or hyaluronic acid may still be covered. Ask each clinic for a written cost estimate and confirm what portion is cash-pay before scheduling.

Ask whether the product is autologous, meaning drawn from your own body that day, and whether any amniotic or umbilical product is being marketed as live stem cells. The FDA has issued warnings about clinics selling such products under unapproved claims. Legitimate practices will walk you through sourcing, processing, and realistic expectations rather than promising cures.

A typical stepwise approach starts with weight management, structured physical therapy, topical or oral anti-inflammatories, and intra-articular corticosteroid or hyaluronic acid injections. For many patients, these control symptoms for years. Regenerative injections are generally considered when conventional measures fail or when the patient wants to delay surgery. Surgical consultation is appropriate for end-stage joint degeneration.

A small but growing subset of clinics employ board-certified rheumatologists or physiatrists alongside regenerative protocols, giving patients one team for diagnosis and injection care. Most of the listings in this directory focus on one side or the other. The listings note scope of practice so patients can choose between a pure regenerative clinic, a rheumatology practice, or a combined model.

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