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151 Best Ketamine Therapy Clinics in Texas

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Read the Ketamine Therapy guide: evidence, costs and questions to ask

Texas

Ketamine Therapy clinics in Texas

Ketamine therapy in Texas is concentrated in the state's major metro areas. Houston, Dallas-Fort Worth, Austin, and San Antonio carry most of the supply, with clinics offering intravenous ketamine infusions, and in some cases esketamine nasal spray delivered under a different protocol. Patients in West Texas, the Panhandle, the Rio Grande Valley, and other areas far from these metros typically have far fewer options nearby and often plan for several hours of travel, an overnight stay, or multiple visits scheduled close together to reduce trips.

Someone searching for how to address chronic pain with ketamine should know that most of the established evidence for ketamine therapy concerns treatment-resistant depression, not pain. Ketamine infusion for chronic pain conditions is used in some Texas clinics, but it is an off-label application with thinner evidence, and results vary by condition and by patient. A page like this cannot tell you which clinic suits a chronic pain case: it can tell you how to read the list and what to ask before you commit.

In Texas, ketamine is a controlled substance, and administering it is generally limited to licensed physicians, physician assistants, and nurse practitioners working under physician oversight, usually in a medical office or a dedicated infusion suite rather than a spa-style setting. Scope of practice rules determine who can order and supervise treatment, so ask directly who is responsible for your care.

Before booking, check a prescriber or supervising physician through the Texas Medical Board, and check nurses through the Texas Board of Nursing. These boards confirm licensing status and public disciplinary history, not clinical skill with ketamine specifically. Ask about credentials and supervision, exactly what medication is used and where it comes from, how risks are disclosed in writing, what happens if treatment does not help, and what an itemized quote covers.

This list's organic order is not for sale. Featured placements are labeled and capped, and a Verified label reflects completed credential checks rather than advertising spend. Regenerated.com is free for patients to use, and appearing in this directory is not an endorsement. The national hub covers how ketamine therapy works and what the evidence supports in more detail: visit it before narrowing to a Texas provider. For more on how to read this list, see How to read a Regenerated city hub and Featured vs Verified vs organic.

151 Clinics, showing page 2 of 11

IVRS Wellness Center
(412)
Physician status unknown

IVRS Wellness Center

Amarillo, TX

IVRS Wellness Center, an IV therapy clinic in Amarillo, offers intravenous nutrient protocols, peptide therapy, and hormone optimization alongside functional-medicine and integrative-medicine workups…

  • Vitamin IV Therapy
  • IV Therapy
  • Ketamine Therapy
  • Cryotherapy
  • Peptide Therapy
Progressive Pain and Interventional Psychiatry
(74)
Physician reported in record

Progressive Pain and Interventional Psychiatry

Dallas, TX

Progressive Pain and Interventional Psychiatry, serving the Dallas area, specializes in ketamine therapy for chronic pain and treatment-resistant conditions. The clinic offers ketamine infusions and …

  • Ketamine Therapy
  • Arthritis Treatment
  • Migraine Treatment
Infuzed Ketamine & IV Therapy
(102)
Physician reported in record

Infuzed Ketamine & IV Therapy

Rosenberg, TX

Infuzed Ketamine & IV Therapy, located in Rosenberg, offers intravenous nutrient therapy, NAD IV infusions, and ketamine therapy. The clinic specializes in IV hydration and vitamin protocols alongsid…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • IV Hydration
  • Ketamine Therapy
Principal Spine
Physician status unknown

Principal Spine

Denton, TX

Principal Spine, a pain management clinic in Dallas, TX, specializes in ketamine therapy alongside regenerative-medicine and spinal cord stimulation for chronic pain, sciatica, and herniated discs. K…

  • Ketamine Therapy
  • Arthritis Treatment
  • Migraine Treatment
DreamWork Wellness Center
(78)
Physician status unknown

DreamWork Wellness Center

Frisco, TX

DreamWork Wellness Center, a Ketamine Therapy Clinic in Frisco, Texas, specializes in ketamine infusion and esketamine (Spravato) for treatment-resistant depression, anxiety, and PTSD, alongside Tran…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Selva Wellness Collective
(23)
Physician reported in record

Selva Wellness Collective

Austin, TX

Selva Wellness Collective, a ketamine-therapy clinic in Austin, offers ketamine-assisted psychotherapy for treatment-resistant depression, anxiety, PTSD, and related mood and trauma presentations. Th…

  • Ketamine Therapy
First Rate Infusion and Wellness- First Rate Ketamine Clinic
(103)
Physician status unknown

First Rate Infusion and Wellness- First Rate Ketamine Clinic

Mesquite, TX

First Rate Infusion and Wellness, an IV therapy and ketamine clinic in Mesquite, specializes in ketamine infusion therapy for treatment-resistant depression, anxiety, and chronic pain, alongside intr…

  • Vitamin IV Therapy
  • PRP Therapy
  • IV Hydration
  • Ketamine Therapy
  • Arthritis Treatment
ReGen & Aesthetics Concierge of Texas
(447)
Physician reported in record

ReGen & Aesthetics Concierge of Texas

Dallas, TX

ReGen & Aesthetics Concierge of Texas, a regenerative medicine and hormone-optimization clinic in Dallas, specializes in bioidentical hormone replacement therapy and testosterone replacement therapy …

  • Shockwave Therapy
  • IV Therapy
  • Ketamine Therapy
  • Peptide Therapy
  • Erectile Dysfunction (ED) Treatment
Nurocoach
(6)
Physician status unknown

Nurocoach

Sugar Land, TX

Nurocoach, a metabolic health and weight-optimization clinic in Sugar Land, Texas, offers ketamine therapy alongside pain management and weight-loss protocols. The clinic specializes in comprehensive…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Neuro Sports Performance and Rehab
Physician status unknown

Neuro Sports Performance and Rehab

San Antonio, TX

Neuro Sports Performance and Rehab, a regenerative-medicine clinic in San Antonio, offers a comprehensive range of cell-based and energy therapies including stem-cell treatments, adipose-derived exos…

  • PRP Therapy
  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Ketamine Therapy
Haracec Complete Healthcare
(131)
Physician reported in record

Haracec Complete Healthcare

El Paso, TX

Haracec Complete Healthcare, a mental-health clinic in El Paso, Texas, specializes in ketamine-assisted therapy for treatment-resistant depression, anxiety, and related conditions. The clinic offers …

  • Vitamin IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Roots Behavioral Health
(249)
Physician reported in record

Roots Behavioral Health

Austin, TX

Roots Behavioral Health, a mental health clinic in Austin, specializes in ketamine therapy and transcranial magnetic stimulation (TMS) for treatment-resistant depression, anxiety, and related mood an…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Advanced Interventional Pain Consultants
(417)
Physician status unknown

Advanced Interventional Pain Consultants

Park Row, TX

Advanced Interventional Pain Consultants, a regenerative pain-management clinic in Houston, offers stem-cell therapy, platelet-rich plasma injections, and ketamine therapy for chronic pain and treatm…

  • PRP Therapy
  • Ketamine Therapy
  • Arthritis Treatment
  • Stem Cell Therapy
OCD Anxiety Centers
(4)
Physician status unknown

OCD Anxiety Centers

The Woodlands, TX

OCD Anxiety Centers, located in The Woodlands, Texas, specializes in intensive outpatient treatment for obsessive-compulsive disorder, anxiety disorders, and related conditions. The clinic offers ket…

  • Ketamine Therapy
Flourish Wellness Center
(154)
Physician reported in record

Flourish Wellness Center

Terrell Hills, TX

Flourish Wellness Center, in San Antonio, offers a comprehensive range of regenerative and supportive-medicine therapies including cell-based treatments, orthobiologics, peptide protocols, and hormon…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • Ozone Therapy
  • IV Therapy
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Regulatory context

A note on Texas's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • HB 1802 / Psilocybin and MDMA Research (2021)
    Required Texas Health and Human Services Commission to study psilocybin and MDMA for PTSD treatment in veterans; report completed.
  • Texas Ibogaine Initiative (HB 3717, 2025 pending)
    Would allocate $50 million for FDA-regulated ibogaine clinical trials, potentially the largest state psychedelic research investment in US history.
  • Texas Controlled Substances Act
    Mirrors federal scheduling.

Texas enforces federal scheduling. The Texas Medical Board oversees prescriber conduct. DEA enforcement on ketamine clinics focuses on diversion and Ryan Haight Act telehealth rules. Texas PMP requires controlled substance reporting. Texas has seen rapid ketamine clinic growth in Austin, Dallas, and Houston markets with corresponding enforcement attention on compounding and telehealth practices.

Ketamine Therapy in , answered.

Ketamine therapy uses low, carefully controlled doses of the anesthetic ketamine, given intravenously or as esketamine nasal spray, to treat depression that has not responded to standard antidepressants. In Texas, treatment is typically delivered in a physician office or infusion suite with monitoring during and after each session. It is not a stand-alone treatment, and most protocols pair it with ongoing psychiatric care and follow-up.

Intravenous ketamine therapy for depression and ketamine infusion for chronic pain use the same medication but different protocols, dosing schedules, and goals, and the evidence base is stronger for depression than for pain. In Texas, both are typically off-label uses decided case by case between you and a prescriber, with dosing set individually rather than by a fixed schedule. Ask any clinic which use they are treating and what evidence supports it for your situation.

Providers are concentrated in Houston, Dallas-Fort Worth, Austin, and San Antonio, with fewer options across rural Texas, the Panhandle, and the Rio Grande Valley. Someone outside these metros should expect to travel, plan around monitored recovery time after each session, and arrange a driver, since you typically cannot drive yourself home afterward. Calling ahead to confirm current availability and scheduling is worthwhile before committing to a trip.

Cost depends on the formulation, the clinical setting, and whether psychotherapy is bundled in, and this page does not publish averages because those costs vary widely across Texas clinics. Intravenous ketamine for depression is commonly cash pay, while esketamine nasal spray may have insurance coverage when specific plan criteria are met. Ask your insurer about authorization first, and request a written quote that itemizes evaluation, medication, monitoring, and follow-up separately.

Ketamine therapy is legal in Texas when administered by licensed professionals operating within their scope of practice; ketamine itself is a controlled substance, not an unregulated wellness product. Administration is generally limited to physicians, physician assistants, and nurse practitioners working under physician oversight, typically in a medical office or infusion suite. Confirm with the clinic who evaluates you, who is physically present during treatment, and who supervises the overall plan.

Physicians and physician assistants can be checked through the Texas Medical Board, and nurses through the Texas Board of Nursing; both publish license status and public disciplinary history online. A clean record confirms standing but does not confirm experience with ketamine specifically or predict how you will respond to treatment. Pair a license check with direct questions about the supervising clinician's training and how recovery and complications are handled.

Ketamine therapy is generally considered for adults with treatment-resistant depression who have tried standard antidepressants without lasting relief, and sometimes for related conditions like bipolar depression under psychiatric supervision; people with certain cardiovascular, psychiatric, or substance use histories are often told to wait or look elsewhere first. Short-term side effects can include dissociation, elevated blood pressure, and nausea during and shortly after a session, and evidence for easing substance use disorders remains limited.

This page gathers clinics across all of Texas rather than one city, so it is useful for comparing regions and deciding whether to travel, while a city page or the national ketamine therapy hub narrows to local detail or to mechanism and evidence. Unlike a general search, organic order here is not for sale, Featured slots are labeled and capped, and a Verified label reflects completed credential checks rather than ad spend.

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