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151 Best Ketamine Therapy Clinics in Texas

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Read the Ketamine Therapy guide: evidence, costs and questions to ask

Texas

Ketamine Therapy clinics in Texas

Ketamine therapy in Texas is concentrated in the state's major metro areas. Houston, Dallas-Fort Worth, Austin, and San Antonio carry most of the supply, with clinics offering intravenous ketamine infusions, and in some cases esketamine nasal spray delivered under a different protocol. Patients in West Texas, the Panhandle, the Rio Grande Valley, and other areas far from these metros typically have far fewer options nearby and often plan for several hours of travel, an overnight stay, or multiple visits scheduled close together to reduce trips.

Someone searching for how to address chronic pain with ketamine should know that most of the established evidence for ketamine therapy concerns treatment-resistant depression, not pain. Ketamine infusion for chronic pain conditions is used in some Texas clinics, but it is an off-label application with thinner evidence, and results vary by condition and by patient. A page like this cannot tell you which clinic suits a chronic pain case: it can tell you how to read the list and what to ask before you commit.

In Texas, ketamine is a controlled substance, and administering it is generally limited to licensed physicians, physician assistants, and nurse practitioners working under physician oversight, usually in a medical office or a dedicated infusion suite rather than a spa-style setting. Scope of practice rules determine who can order and supervise treatment, so ask directly who is responsible for your care.

Before booking, check a prescriber or supervising physician through the Texas Medical Board, and check nurses through the Texas Board of Nursing. These boards confirm licensing status and public disciplinary history, not clinical skill with ketamine specifically. Ask about credentials and supervision, exactly what medication is used and where it comes from, how risks are disclosed in writing, what happens if treatment does not help, and what an itemized quote covers.

This list's organic order is not for sale. Featured placements are labeled and capped, and a Verified label reflects completed credential checks rather than advertising spend. Regenerated.com is free for patients to use, and appearing in this directory is not an endorsement. The national hub covers how ketamine therapy works and what the evidence supports in more detail: visit it before narrowing to a Texas provider. For more on how to read this list, see How to read a Regenerated city hub and Featured vs Verified vs organic.

151 Clinics, showing page 7 of 11

(104)
Physician status unknown

Heading Health Ketamine Center

Dallas, TX

Heading Health Ketamine Center, based in Dallas, offers Ketamine Therapy and Transcranial Magnetic Stimulation (TMS) for treatment-resistant depression and related mood disorders. The clinic provides…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Active Life Hormone Therapy & Weight Loss
(25)
Physician reported in record

Active Life Hormone Therapy & Weight Loss

Humble, TX

Active Life Hormone Therapy & Weight Loss, a hormone optimization clinic in Kingwood, Texas, specializes in bioidentical hormone replacement therapy (BHRT), testosterone replacement therapy (TRT), an…

  • IV Therapy
  • IV Hydration
  • Ketamine Therapy
  • Peptide Therapy
  • Erectile Dysfunction (ED) Treatment
Impact Infusions
(16)
Physician status unknown

Impact Infusions

Argyle, TX

Impact Infusions, a ketamine therapy clinic in Argyle, offers intravenous ketamine infusions for treatment-resistant depression, anxiety, and post-traumatic stress disorder. The clinic serves patient…

  • Ketamine Therapy
Your Wellness Practice - Integrative Psychiatry, Ketamine, TMS.
(8)
Physician status unknown

Your Wellness Practice - Integrative Psychiatry, Ketamine, TMS.

Houston, TX

Your Wellness Practice—Integrative Psychiatry, Ketamine, TMS in Houston specializes in ketamine-assisted therapy for treatment-resistant depression, anxiety, and PTSD, alongside transcranial magnetic…

  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Neurofeedback Therapy
  • Ketamine Therapy
  • Hormone Replacement Therapy (HRT)
Arthritis Relief Institute
(24)
Physician status unknown

Arthritis Relief Institute

Dallas, TX

Arthritis Relief Institute in Dallas specializes in regenerative approaches to chronic musculoskeletal pain and arthritis, offering platelet-rich plasma therapy alongside ketamine treatment. PRP inje…

  • PRP Therapy
  • Ketamine Therapy
  • Arthritis Treatment
(57)
Physician reported in record

Heading Health Ketamine Center

San Antonio, TX

Heading Health Ketamine Center, located in San Antonio, specializes in ketamine therapy and Spravato (esketamine) for treatment-resistant depression, anxiety, and post-traumatic stress. The clinic of…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Andala Health
Physician reported in record

Andala Health

Shavano Park, TX

Andala Health, a ketamine-therapy clinic in San Antonio, offers esketamine and ketamine infusion for treatment-resistant depression, anxiety, and PTSD alongside complementary supportive-medicine serv…

  • IV Therapy
  • Ketamine Therapy
  • Peptide Therapy
  • Hormone Replacement Therapy (HRT)
Sauna Therapy
(14)
Physician reported in record

Sauna Therapy

Dallas, TX

Sauna Therapy, a mental-health clinic in Dallas, offers ketamine-assisted psychotherapy alongside traditional talk therapy modalities including somatic work, EMDR, and creative counseling approaches.…

  • Ketamine Therapy
Roots Behavioral Health - Lost Creek - A Hightop Health Clinic
(70)
Physician reported in record

Roots Behavioral Health - Lost Creek - A Hightop Health Clinic

Rollingwood, TX

Roots Behavioral Health – Lost Creek, a ketamine-assisted-therapy clinic in Austin, specializes in Ketamine Therapy and Ketamine-Assisted Psychotherapy alongside integrative psychiatry and psychother…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Psychedelic Therapy
Texas Ketamine & Wellness Center
(71)
Physician reported in record

Texas Ketamine & Wellness Center

Houston, TX

Texas Ketamine & Wellness Center, located in Houston, offers physician-guided ketamine therapy for treatment-resistant depression, PTSD, anxiety, obsessive-compulsive disorder, and chronic pain condi…

  • IV Therapy
  • Ketamine Therapy
  • Migraine Treatment
Neogen Psychiatry & TMS
(8)
Physician status unknown

Neogen Psychiatry & TMS

Fort Worth, TX

Neogen Psychiatry & TMS, a mental health practice in Southlake, Texas, specializes in Transcranial Magnetic Stimulation (TMS) and Spravato Esketamine treatment for patients with treatment-resistant d…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Texas Mind Science
Physician reported in record

Texas Mind Science

Frisco, TX

Texas Mind Science, a Ketamine Therapy and Transcranial Magnetic Stimulation clinic in Frisco, offers ketamine infusions and TMS protocols for treatment-resistant depression, anxiety, PTSD, and chron…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Diamond Hormone Replacement Therapy
(5)
Physician status unknown

Diamond Hormone Replacement Therapy

El Paso, TX

Diamond Hormone Replacement Therapy, an integrative hormone-optimization clinic in El Paso, specializes in bioidentical hormone replacement therapy and testosterone replacement therapy for men and wo…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • IV Hydration
  • Ketamine Therapy
Bespoke Health - Relief, tailored to you.
(10)
Physician reported in record

Bespoke Health - Relief, tailored to you.

Piney Point, TX

Bespoke Health, an IV therapy clinic in Houston, specializes in intravenous nutrient protocols and NAD IV therapy for patients managing chronic fatigue and seeking supportive care. The practice offer…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • IV Hydration
  • Ketamine Therapy
Ebb & Flow Depth Psychotherapy
(6)
Physician status unknown

Ebb & Flow Depth Psychotherapy

Rollingwood, TX

Ebb & Flow Depth Psychotherapy, a ketamine-assisted therapy clinic in Austin, combines ketamine protocols with depth-oriented psychotherapy rooted in Jungian and psychodynamic traditions. The practic…

  • Ketamine Therapy
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Regulatory context

A note on Texas's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • HB 1802 / Psilocybin and MDMA Research (2021)
    Required Texas Health and Human Services Commission to study psilocybin and MDMA for PTSD treatment in veterans; report completed.
  • Texas Ibogaine Initiative (HB 3717, 2025 pending)
    Would allocate $50 million for FDA-regulated ibogaine clinical trials, potentially the largest state psychedelic research investment in US history.
  • Texas Controlled Substances Act
    Mirrors federal scheduling.

Texas enforces federal scheduling. The Texas Medical Board oversees prescriber conduct. DEA enforcement on ketamine clinics focuses on diversion and Ryan Haight Act telehealth rules. Texas PMP requires controlled substance reporting. Texas has seen rapid ketamine clinic growth in Austin, Dallas, and Houston markets with corresponding enforcement attention on compounding and telehealth practices.

Ketamine Therapy in , answered.

Ketamine therapy uses low, carefully controlled doses of the anesthetic ketamine, given intravenously or as esketamine nasal spray, to treat depression that has not responded to standard antidepressants. In Texas, treatment is typically delivered in a physician office or infusion suite with monitoring during and after each session. It is not a stand-alone treatment, and most protocols pair it with ongoing psychiatric care and follow-up.

Intravenous ketamine therapy for depression and ketamine infusion for chronic pain use the same medication but different protocols, dosing schedules, and goals, and the evidence base is stronger for depression than for pain. In Texas, both are typically off-label uses decided case by case between you and a prescriber, with dosing set individually rather than by a fixed schedule. Ask any clinic which use they are treating and what evidence supports it for your situation.

Providers are concentrated in Houston, Dallas-Fort Worth, Austin, and San Antonio, with fewer options across rural Texas, the Panhandle, and the Rio Grande Valley. Someone outside these metros should expect to travel, plan around monitored recovery time after each session, and arrange a driver, since you typically cannot drive yourself home afterward. Calling ahead to confirm current availability and scheduling is worthwhile before committing to a trip.

Cost depends on the formulation, the clinical setting, and whether psychotherapy is bundled in, and this page does not publish averages because those costs vary widely across Texas clinics. Intravenous ketamine for depression is commonly cash pay, while esketamine nasal spray may have insurance coverage when specific plan criteria are met. Ask your insurer about authorization first, and request a written quote that itemizes evaluation, medication, monitoring, and follow-up separately.

Ketamine therapy is legal in Texas when administered by licensed professionals operating within their scope of practice; ketamine itself is a controlled substance, not an unregulated wellness product. Administration is generally limited to physicians, physician assistants, and nurse practitioners working under physician oversight, typically in a medical office or infusion suite. Confirm with the clinic who evaluates you, who is physically present during treatment, and who supervises the overall plan.

Physicians and physician assistants can be checked through the Texas Medical Board, and nurses through the Texas Board of Nursing; both publish license status and public disciplinary history online. A clean record confirms standing but does not confirm experience with ketamine specifically or predict how you will respond to treatment. Pair a license check with direct questions about the supervising clinician's training and how recovery and complications are handled.

Ketamine therapy is generally considered for adults with treatment-resistant depression who have tried standard antidepressants without lasting relief, and sometimes for related conditions like bipolar depression under psychiatric supervision; people with certain cardiovascular, psychiatric, or substance use histories are often told to wait or look elsewhere first. Short-term side effects can include dissociation, elevated blood pressure, and nausea during and shortly after a session, and evidence for easing substance use disorders remains limited.

This page gathers clinics across all of Texas rather than one city, so it is useful for comparing regions and deciding whether to travel, while a city page or the national ketamine therapy hub narrows to local detail or to mechanism and evidence. Unlike a general search, organic order here is not for sale, Featured slots are labeled and capped, and a Verified label reflects completed credential checks rather than ad spend.

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