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151 Best Ketamine Therapy Clinics in Texas

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Read the Ketamine Therapy guide: evidence, costs and questions to ask

Texas

Ketamine Therapy clinics in Texas

Ketamine therapy in Texas is concentrated in the state's major metro areas. Houston, Dallas-Fort Worth, Austin, and San Antonio carry most of the supply, with clinics offering intravenous ketamine infusions, and in some cases esketamine nasal spray delivered under a different protocol. Patients in West Texas, the Panhandle, the Rio Grande Valley, and other areas far from these metros typically have far fewer options nearby and often plan for several hours of travel, an overnight stay, or multiple visits scheduled close together to reduce trips.

Someone searching for how to address chronic pain with ketamine should know that most of the established evidence for ketamine therapy concerns treatment-resistant depression, not pain. Ketamine infusion for chronic pain conditions is used in some Texas clinics, but it is an off-label application with thinner evidence, and results vary by condition and by patient. A page like this cannot tell you which clinic suits a chronic pain case: it can tell you how to read the list and what to ask before you commit.

In Texas, ketamine is a controlled substance, and administering it is generally limited to licensed physicians, physician assistants, and nurse practitioners working under physician oversight, usually in a medical office or a dedicated infusion suite rather than a spa-style setting. Scope of practice rules determine who can order and supervise treatment, so ask directly who is responsible for your care.

Before booking, check a prescriber or supervising physician through the Texas Medical Board, and check nurses through the Texas Board of Nursing. These boards confirm licensing status and public disciplinary history, not clinical skill with ketamine specifically. Ask about credentials and supervision, exactly what medication is used and where it comes from, how risks are disclosed in writing, what happens if treatment does not help, and what an itemized quote covers.

This list's organic order is not for sale. Featured placements are labeled and capped, and a Verified label reflects completed credential checks rather than advertising spend. Regenerated.com is free for patients to use, and appearing in this directory is not an endorsement. The national hub covers how ketamine therapy works and what the evidence supports in more detail: visit it before narrowing to a Texas provider. For more on how to read this list, see How to read a Regenerated city hub and Featured vs Verified vs organic.

151 Clinics, showing page 8 of 11

Principle Spine and Pain
(43)
Physician status unknown

Principle Spine and Pain

Houston, TX

Principle Spine and Pain, a pain management clinic in the Houston area, offers stem-cell therapy and ketamine therapy for patients with chronic pain and treatment-resistant conditions. The clinic com…

  • Ketamine Therapy
  • Arthritis Treatment
  • Migraine Treatment
  • Stem Cell Therapy
Way Out West Spine + Mobility
(141)
Physician reported in record

Way Out West Spine + Mobility

Fort Worth, TX

Way Out West Spine + Mobility, a pain-management clinic in Fort Worth, specializes in ketamine therapy for chronic pain and treatment-resistant conditions. The practice offers ketamine infusions as p…

  • Ketamine Therapy
  • Arthritis Treatment
  • Migraine Treatment
Michael Shiekh, MD
(4)
Physician reported in record

Michael Shiekh, MD

Dallas, TX

Dr. Michael Shiekh, a board-certified psychiatrist in Dallas, specializes in ketamine therapy and esketamine (Spravato) for treatment-resistant depression and anxiety. The practice offers both intran…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Fort Worth TMS Center
(4)
Physician reported in record

Fort Worth TMS Center

Fort Worth, TX

Fort Worth TMS Center, operated by psychiatrist Diana Ghelber, MD, specializes in transcranial magnetic stimulation and ketamine therapy for treatment-resistant depression, anxiety, and related condi…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Meraki Holistic Counseling
(1)
Physician status unknown

Meraki Holistic Counseling

San Antonio, TX

Meraki Holistic Counseling, a ketamine-assisted therapy clinic in San Antonio, offers ketamine therapy alongside Eye Movement Desensitization and Reprocessing (EMDR) for trauma, burnout, and perfecti…

  • Ketamine Therapy
Zoe Psychiatry & Sleep Medicine
(4)
Physician status unknown

Zoe Psychiatry & Sleep Medicine

Dallas, TX

Zoe Psychiatry & Sleep Medicine, in Dallas, offers Transcranial Magnetic Stimulation for treatment-resistant depression and anxiety alongside comprehensive sleep-medicine evaluation and Sleep Apnea T…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Sleep Apnea Treatment
La Mente Behavioral Health
(96)
Physician reported in record

La Mente Behavioral Health

El Paso, TX

La Mente Behavioral Health, in El Paso, offers Spravato and transcranial magnetic stimulation (TMS) for patients with treatment-resistant depression and related mood conditions. The clinic combines t…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Klarisana
(105)
Physician reported in record

Klarisana

San Antonio, TX

Klarisana, a ketamine-assisted therapy clinic in San Antonio, offers esketamine (Spravato) and ketamine treatment for treatment-resistant depression, anxiety, and chronic pain. The clinic combines ph…

  • Ketamine Therapy
Our Psyche
(8)
Physician status unknown

Our Psyche

Edinburg, TX

Our Psyche, a ketamine-therapy clinic in Edinburg, Texas, offers ketamine-assisted psychotherapy for treatment-resistant depression, anxiety, and related conditions. The practice combines pharmacolog…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Redefined Mind
(62)
Physician status unknown

Redefined Mind

Cypress, TX

Redefined Mind, a brain-treatment clinic in Cypress serving the Houston area, specializes in Ketamine Therapy and Magnetic e-Resonance Therapy (MeRT) for neurological and psychiatric conditions. Keta…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Precision Wellness Center
(67)
Physician reported in record

Precision Wellness Center

Plano, TX

Precision Wellness Center, a hormone and peptide-optimization clinic in Plano, specializes in bioidentical hormone replacement therapy for men and women, alongside peptide protocols including semaglu…

  • IV Hydration
  • Ketamine Therapy
  • Peptide Therapy
  • Hormone Replacement Therapy (HRT)
  • NAD IV Therapy
(13)
Physician reported in record

Peak Life Health

Dallas, TX

Peak Life Health, a peptide and hormone optimization clinic in Dallas, specializes in bioidentical hormone replacement therapy for men and women, alongside platelet-rich plasma therapy and exosome tr…

  • PRP Therapy
  • Ketamine Therapy
  • Arthritis Treatment
  • Erectile Dysfunction (ED) Treatment
  • Hormone Replacement Therapy (HRT)
Trauma to Wellness Counseling
Physician status unknown

Trauma to Wellness Counseling

Dallas, TX

Trauma to Wellness Counseling, located in Dallas, offers Ketamine Therapy alongside EMDR and other psychotherapy modalities for adults addressing trauma, abuse, and relationship recovery. The practic…

  • Ketamine Therapy
Pain and Spine Physicians
(723)
Physician reported in record

Pain and Spine Physicians

Lewisville, TX

Pain and Spine Physicians, located in Flower Mound, specializes in regenerative medicine and ketamine therapy for chronic musculoskeletal pain and spine-related conditions. The practice offers regene…

  • Ketamine Therapy
  • Arthritis Treatment
  • Migraine Treatment
Lubbock Integrative Medical & Aesthetics
(33)
Physician status unknown

Lubbock Integrative Medical & Aesthetics

Lubbock, TX

Lubbock Integrative Medical & Aesthetics, a regenerative-medicine practice in Lubbock, offers stem-cell therapy, platelet-rich plasma injections, and hormone-replacement therapy alongside IV therapy …

  • PRP Therapy
  • IV Therapy
  • Ketamine Therapy
  • Hormone Replacement Therapy (HRT)
  • Stem Cell Therapy
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Regulatory context

A note on Texas's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • HB 1802 / Psilocybin and MDMA Research (2021)
    Required Texas Health and Human Services Commission to study psilocybin and MDMA for PTSD treatment in veterans; report completed.
  • Texas Ibogaine Initiative (HB 3717, 2025 pending)
    Would allocate $50 million for FDA-regulated ibogaine clinical trials, potentially the largest state psychedelic research investment in US history.
  • Texas Controlled Substances Act
    Mirrors federal scheduling.

Texas enforces federal scheduling. The Texas Medical Board oversees prescriber conduct. DEA enforcement on ketamine clinics focuses on diversion and Ryan Haight Act telehealth rules. Texas PMP requires controlled substance reporting. Texas has seen rapid ketamine clinic growth in Austin, Dallas, and Houston markets with corresponding enforcement attention on compounding and telehealth practices.

Ketamine Therapy in , answered.

Ketamine therapy uses low, carefully controlled doses of the anesthetic ketamine, given intravenously or as esketamine nasal spray, to treat depression that has not responded to standard antidepressants. In Texas, treatment is typically delivered in a physician office or infusion suite with monitoring during and after each session. It is not a stand-alone treatment, and most protocols pair it with ongoing psychiatric care and follow-up.

Intravenous ketamine therapy for depression and ketamine infusion for chronic pain use the same medication but different protocols, dosing schedules, and goals, and the evidence base is stronger for depression than for pain. In Texas, both are typically off-label uses decided case by case between you and a prescriber, with dosing set individually rather than by a fixed schedule. Ask any clinic which use they are treating and what evidence supports it for your situation.

Providers are concentrated in Houston, Dallas-Fort Worth, Austin, and San Antonio, with fewer options across rural Texas, the Panhandle, and the Rio Grande Valley. Someone outside these metros should expect to travel, plan around monitored recovery time after each session, and arrange a driver, since you typically cannot drive yourself home afterward. Calling ahead to confirm current availability and scheduling is worthwhile before committing to a trip.

Cost depends on the formulation, the clinical setting, and whether psychotherapy is bundled in, and this page does not publish averages because those costs vary widely across Texas clinics. Intravenous ketamine for depression is commonly cash pay, while esketamine nasal spray may have insurance coverage when specific plan criteria are met. Ask your insurer about authorization first, and request a written quote that itemizes evaluation, medication, monitoring, and follow-up separately.

Ketamine therapy is legal in Texas when administered by licensed professionals operating within their scope of practice; ketamine itself is a controlled substance, not an unregulated wellness product. Administration is generally limited to physicians, physician assistants, and nurse practitioners working under physician oversight, typically in a medical office or infusion suite. Confirm with the clinic who evaluates you, who is physically present during treatment, and who supervises the overall plan.

Physicians and physician assistants can be checked through the Texas Medical Board, and nurses through the Texas Board of Nursing; both publish license status and public disciplinary history online. A clean record confirms standing but does not confirm experience with ketamine specifically or predict how you will respond to treatment. Pair a license check with direct questions about the supervising clinician's training and how recovery and complications are handled.

Ketamine therapy is generally considered for adults with treatment-resistant depression who have tried standard antidepressants without lasting relief, and sometimes for related conditions like bipolar depression under psychiatric supervision; people with certain cardiovascular, psychiatric, or substance use histories are often told to wait or look elsewhere first. Short-term side effects can include dissociation, elevated blood pressure, and nausea during and shortly after a session, and evidence for easing substance use disorders remains limited.

This page gathers clinics across all of Texas rather than one city, so it is useful for comparing regions and deciding whether to travel, while a city page or the national ketamine therapy hub narrows to local detail or to mechanism and evidence. Unlike a general search, organic order here is not for sale, Featured slots are labeled and capped, and a Verified label reflects completed credential checks rather than ad spend.

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