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29 Best Arthritis Treatment Clinics in San Francisco, California

Every listing is checked against federal records, reviewed for evidence, and confirmed still operating. No pay-to-play. No guesswork.

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San Francisco, CA

Arthritis Treatment clinics in San Francisco

San Francisco is a Bay Area market that blends UCSF-affiliated specialists with a thoughtful integrative medicine scene across the city and the Peninsula. Patients dealing with osteoarthritis, inflammatory arthritis, or post-injury joint degeneration can access both traditional pathways and newer biologic options without leaving the area.

On the regenerative side, clinics commonly offer platelet-rich plasma injections, bone marrow aspirate concentrate, and prolotherapy for mild to moderate osteoarthritis. Evidence for these is best described as Emerging for knee and hip osteoarthritis and Insufficient for most other joints. For inflammatory arthritis such as rheumatoid or psoriatic disease, conventional biologics remain the standard of care with Strong evidence, and regenerative injections are typically considered adjunctive rather than primary.

The clinics listed below have been reviewed for basic credentialing and transparency. Confirm physician specialty and evidence discussion before any injection series.

29 Clinics, showing page 1 of 2

Integrated Healing Medicine and Wellness

San Francisco, CA

Integrated Healing Medicine and Wellness, a functional and integrative-medicine clinic in San Francisco, offers cell-based therapies including stem-cell and exosome treatment alongside platelet-rich …

  • PRP Therapy
  • Arthritis Treatment
  • Peptide Therapy
  • Stem Cell Therapy
MD on staff

Azzolino Chiropractic Neurology & Integrative Wellness

San Francisco, CA

Azzolino Chiropractic Neurology & Integrative Wellness, a functional and integrative medicine clinic in San Francisco, combines chiropractic care with functional neurology, rehabilitation, and naturo…

  • Ozone Therapy
  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy

Ocean Chiropractic Center

San Francisco, CA

Ocean Chiropractic Center, a regenerative physical-medicine clinic in San Francisco, specializes in Shockwave Therapy for musculoskeletal conditions and soft-tissue injuries. Shockwave therapy uses a…

  • Shockwave Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment
  • Migraine Treatment
MD on staff

RegenCore

San Francisco, CA

Dr. Rowan V. Paul, MD, a regenerative medicine clinic in San Francisco, specializes in platelet-rich plasma therapy and shockwave therapy for musculoskeletal pain and soft-tissue injuries. The practi…

  • PRP Therapy
  • Shockwave Therapy
  • Arthritis Treatment
  • Stem Cell Therapy
MD on staff

Physicians' Back Institute

San Francisco, CA

Physicians' Back Institute, a pain-management practice in San Francisco, specializes in prolotherapy and regenerative injection for musculoskeletal and spine conditions. The clinic combines functiona…

  • Arthritis Treatment
  • Migraine Treatment
MD on staff

Stone Research Foundation

San Francisco, CA

Stone Research Foundation, a regenerative medicine clinic in San Francisco, focuses on stem-cell therapy and NAD IV therapy alongside integrative treatment protocols for orthopaedic and joint conditi…

  • Arthritis Treatment
  • Stem Cell Therapy
  • NAD IV Therapy

Zaré Medical Naturopathic Group

San Francisco, CA

Zaré Medical Naturopathic Group, a naturopathic-medicine clinic in San Francisco, offers evidence-based natural approaches to chronic health conditions and wellness optimization. The practice emphasi…

  • PRP Therapy
  • IV Therapy
  • Arthritis Treatment
  • Hormone Replacement Therapy (HRT)
MD on staff

Sfsportsdoc

San Francisco, CA

SF Sports Doc, a regenerative medicine clinic in San Francisco, specializes in orthobiologic therapies for musculoskeletal and sports-related injuries. The practice offers platelet-rich plasma therap…

  • PRP Therapy
  • Arthritis Treatment
  • Stem Cell Therapy
MD on staff

Golden Gate Stem Cell

San Francisco, CA

Golden Gate Stem Cell, a regenerative medicine clinic in San Francisco, specializes in stem-cell therapy and platelet-rich plasma injections for musculoskeletal and joint conditions. The practice off…

  • PRP Therapy
  • Arthritis Treatment
  • Stem Cell Therapy
MD on staff

Th Stone Clinic

San Francisco, CA

The Stone Clinic, led by orthopedic surgeon Kevin R. Stone, MD, specializes in regenerative injection therapy and shockwave therapy for musculoskeletal injuries and arthritis affecting the knee, shou…

  • PRP Therapy
  • Shockwave Therapy
  • Arthritis Treatment
  • Stem Cell Therapy

Thriving Life Wellness Center

San Francisco, CA

Thriving Life Wellness Center, a musculoskeletal and pain clinic in San Francisco, offers acupuncture and shockwave therapy for patients with chronic pain and soft-tissue injuries. Shockwave therapy …

  • Shockwave Therapy
  • Arthritis Treatment
  • Migraine Treatment
  • TMJ Treatment
MD on staff

Robert Mayle MD, Orthopaedic Hip and Knee Surgeon, San

San Francisco, CA

Robert Mayle MD is an orthopaedic surgeon in San Francisco specializing in hip and knee conditions. The practice offers platelet-rich plasma therapy and stem-cell injections for musculoskeletal and j…

  • PRP Therapy
  • Arthritis Treatment
  • Stem Cell Therapy
MD on staff

Leena Pandya, ND BCB

San Francisco, CA

Leena Pandya, ND BCB, a functional-medicine practice in San Francisco, offers integrative treatment combining regenerative orthobiologics with hormone optimization and IV therapy. The clinic speciali…

  • Biofeedback Therapy
  • PRP Therapy
  • IV Therapy
  • Arthritis Treatment
  • Peptide Therapy

Silver Sports Therapy

San Francisco, CA

Silver Sports Therapy, a regenerative sports medicine practice in San Francisco, specializes in platelet-rich plasma therapy and shockwave treatment for musculoskeletal injuries and chronic soft-tiss…

  • PRP Therapy
  • Shockwave Therapy
  • Arthritis Treatment

Terapia Celular del Perú

San Francisco, CA

Terapia Celular del Perú, a regenerative medicine clinic in San Francisco, offers stem-cell therapy, platelet-rich plasma injections, and ozone therapy for tissue repair and age-related decline. The …

  • PRP Therapy
  • Ozone Therapy
  • IV Therapy
  • Laser Therapy (LLLT)
  • Arthritis Treatment

Regulatory context

A note on California's arthritis treatment rules.

The "other" category is a catchall for regenerative wellness modalities with inconsistent federal oversight. Red light therapy devices (photobiomodulation) have narrow FDA 510(k) clearances for acne, muscle pain, and wound healing, not systemic regeneration. Whole-body cryotherapy is NOT FDA-approved for any medical indication and received an FDA safety communication in July 2016 warning of asphyxiation, frostbite, and burn risks. Ozone therapy is NOT FDA-approved for any medical use and the FDA has stated ozone is a toxic gas with no known useful medical application. Condition-specific regenerative offerings (hair restoration with minoxidil or finasteride, ED care beyond PDE5 inhibitors and shockwave) have varying approval depending on route and drug source.

  • California Medical Practice Act (Bus. & Prof. Code §§ 2000-2529)
    Defines medical practice and corporate practice of medicine prohibitions strictly enforced against lay-owned medical spas.
  • California Business & Professions Code §§ 2051-2052
    Prohibits unlicensed practice of medicine and aiding and abetting by non-physician owners.
  • Board of Registered Nursing Standardized Procedures (CCR Title 16 § 1474)
    Requires physician-developed standardized procedures for RNs performing cosmetic and wellness injections or laser work.

California is among the strictest enforcement states. The Medical Board of California has issued public advisories and taken disciplinary action against medical spas for corporate practice of medicine violations, unsupervised RN injections, and false advertising of unapproved therapies. Ozone therapy is heavily scrutinized and clinics making cancer or infection treatment claims risk board discipline and Attorney General consumer protection action. The California Department of Public Health and local health departments also investigate facility and infection control issues at wellness clinics.

Arthritis Treatment in San Francisco, answered.

Knee and hip osteoarthritis have the most supportive data for platelet-rich plasma and bone marrow aspirate concentrate, though evidence is still considered Emerging rather than Strong. Thumb basal joint and shoulder osteoarthritis have smaller case series. Inflammatory arthritis such as rheumatoid disease requires systemic immunomodulation first, with regenerative injections used only as a local adjunct in specific joints after disease activity is controlled.

In most cases, no. Platelet-rich plasma, bone marrow aspirate, and adipose-derived procedures for arthritis are generally classified as investigational by commercial insurers and Medicare. Some diagnostic imaging, office visits, and conventional injections like corticosteroids or hyaluronic acid may still be covered. Ask each clinic for a written cost estimate and confirm what portion is cash-pay before scheduling.

Ask whether the product is autologous, meaning drawn from your own body that day, and whether any amniotic or umbilical product is being marketed as live stem cells. The FDA has issued warnings about clinics selling such products under unapproved claims. Legitimate practices will walk you through sourcing, processing, and realistic expectations rather than promising cures.

A typical stepwise approach starts with weight management, structured physical therapy, topical or oral anti-inflammatories, and intra-articular corticosteroid or hyaluronic acid injections. For many patients, these control symptoms for years. Regenerative injections are generally considered when conventional measures fail or when the patient wants to delay surgery. Surgical consultation is appropriate for end-stage joint degeneration.

A small but growing subset of clinics employ board-certified rheumatologists or physiatrists alongside regenerative protocols, giving patients one team for diagnosis and injection care. Most of the listings in this directory focus on one side or the other. The listings note scope of practice so patients can choose between a pure regenerative clinic, a rheumatology practice, or a combined model.

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