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218 Best Ketamine Therapy Clinics in California

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Read the Ketamine Therapy guide: evidence, costs and questions to ask

What does this directory page list?

This page lists directory records associated with Ketamine Therapy in California. A browsing area can include nearby municipalities. Confirm each clinic's street address and current services directly.

Matching records:
218. Source: the current directory result set, including pages beyond this screen.
Treatment filter:
Ketamine Therapy.
Source limits:
Listing information is not an independent clinic evaluation. Record updates do not establish field-level check dates.

Read the Ketamine Therapy guide for the educational context behind this treatment category.

California

Ketamine Therapy clinics in California

Searching for a ketamine clinic in California turns up supply concentrated in a few metro regions rather than spread evenly across the state. The Los Angeles area and the greater Bay Area carry most of California's ketamine therapy capacity, with San Diego and Sacramento adding further options. The Central Valley, the far north, and much of the Inland Empire have comparatively little, so someone outside these population centers should expect to travel, sometimes considerably, to reach an established provider.

California has no ketamine-specific licensing statute beyond the general rules already governing controlled substances. A physician or a supervised physician assistant typically orders and oversees treatment, and a registered nurse or nurse practitioner may administer it as part of that medical team. Treatment is usually delivered in a physician's office or a dedicated infusion suite with monitoring equipment, rather than a purely wellness setting, though wellness-branded locations do exist. Scope of practice for nurse practitioners varies with their supervision agreement, so confirm who is actually present during your session.

To verify a provider, check physicians and physician assistants through the Medical Board of California or, for osteopathic physicians, the Osteopathic Medical Board of California. Check nurses and nurse practitioners through the California Board of Registered Nursing. A clean license record shows someone is permitted to practice; it does not establish ketamine-specific experience or predict how you will respond to treatment.

Before booking, ask who evaluates you, who is present and supervising during the infusion, what is being administered and where it is sourced, and how risks are disclosed in writing. Ask what happens if treatment does not help, and request an itemized quote covering evaluation, medication, monitoring, and any included therapy or follow-up.

This listing's order is not for sale. Featured slots are labeled and limited in number, Verified means a clinic has completed credential checks rather than paid for placement, and browsing Regenerated.com costs patients nothing. Appearing in this directory is not an endorsement of any listed clinic.

The national ketamine therapy hub covers the mechanism and the evidence behind IV ketamine and nasal esketamine in more depth. For more on how to read a listing like this one, see How to read a Regenerated city hub and Featured vs Verified vs organic.

218 Clinics, showing page 1 of 15

(39)
Physician status unknown

Golden Afternoon Ketamine Clinic - Los Angeles

Santa Monica, CA

Golden Afternoon Ketamine Clinic, located in Santa Monica, specializes in ketamine therapy and intranasal esketamine (Spravato) for treatment-resistant depression, anxiety, and PTSD. The clinic offer…

  • IV Therapy
  • Ketamine Therapy
Roots Mental Health Treatment Center
(18)
Physician reported in record

Roots Mental Health Treatment Center

Long Beach, CA

Roots Mental Health Treatment Center of Long Beach, in Long Beach, California, specializes in ketamine therapy for treatment-resistant depression, anxiety, and post-traumatic stress disorder. The cli…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Psychedelic Therapy
Santa Cruz CORE Fitness + Rehab
(108)
Physician reported in record

Santa Cruz CORE Fitness + Rehab

Bonny Doon, CA

Santa Cruz CORE Fitness + Rehab, a regenerative medicine clinic in Santa Cruz, offers a comprehensive range of cell-based and orthobiologic therapies including stem-cell therapy, platelet-rich plasma…

  • PRP Therapy
  • Shockwave Therapy
  • IV Therapy
  • Laser Therapy (LLLT)
  • Hyperbaric Oxygen Therapy (HBOT)
Velara Wellness
(23)
Physician status unknown

Velara Wellness

San Diego, CA

Velara Wellness, a ketamine and psychedelic-assisted therapy clinic in San Diego, offers Ketamine Infusion Therapy, Spravato (intranasal esketamine), and Transcranial Magnetic Stimulation for treatme…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Psychedelic Therapy
Better U
(127)
Physician reported in record

Better U

West Hollywood, CA

Better U, a ketamine-therapy clinic in West Hollywood, offers Ketamine Therapy for treatment-resistant depression, anxiety, and related conditions. The practice provides at-home ketamine treatment fo…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • Ketamine Therapy
  • Chelation Therapy
  • Peptide Therapy
Center for Healthy Sex
(18)
Physician status unknown

Center for Healthy Sex

West Los Angeles, CA

Center for Healthy Sex, a mental-health clinic in Los Angeles, specializes in sex therapy and sex-addiction treatment using ketamine-assisted psychotherapy protocols. The clinic offers ketamine thera…

  • Ketamine Therapy
  • Erectile Dysfunction (ED) Treatment
Silverlining Psychiatry
(13)
Physician reported in record

Silverlining Psychiatry

San Diego, CA

Silverlining Psychiatry, in San Diego, provides evidence-based adult psychiatry with a focus on Ketamine Therapy, Spravato (esketamine nasal spray), and Transcranial Magnetic Stimulation (TMS) for tr…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Ashvind Adkins Singh
(1)
Physician status unknown

Ashvind Adkins Singh

Long Beach, CA

Dr. Ashvind Adkins Singh, a licensed clinical psychologist in Long Beach, offers Ketamine Therapy for patients with treatment-resistant depression, anxiety, and trauma-related conditions. The practic…

  • Ketamine Therapy
Reset Ketamine
(40)
Physician reported in record

Reset Ketamine

Palm Springs, CA

Reset Ketamine, a ketamine-therapy clinic in Palm Springs, offers ketamine infusions for treatment-resistant depression, anxiety, obsessive-compulsive disorder, post-traumatic stress disorder, and ch…

  • Ketamine Therapy
Concierge Ketamine
(2)
Physician status unknown

Concierge Ketamine

La Jolla, CA

Concierge Ketamine, a ketamine-therapy clinic in La Jolla, offers ketamine infusions and IV therapy for treatment-resistant depression, anxiety, and PTSD. Treatment protocols are individualized follo…

  • IV Therapy
  • Ketamine Therapy
Dr. Elizabeth Wolfson
(2)
Physician status unknown

Dr. Elizabeth Wolfson

Santa Barbara, CA

Dr. Elizabeth Wolfson, in Santa Barbara, offers ketamine-assisted psychotherapy for treatment-resistant depression, anxiety, PTSD, and related conditions. The practice combines ketamine administratio…

  • Ketamine Therapy
Family Psychiatry, Counseling and Wellness
(178)
Physician reported in record

Family Psychiatry, Counseling and Wellness

Thousand Oaks, CA

Family Psychiatry, Counseling and Wellness, a mental-health clinic in Westlake Village, California, offers Transcranial Magnetic Stimulation (TMS) and Ketamine Therapy alongside conventional psychiat…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Proprius Health Medical Group
Physician reported in record

Proprius Health Medical Group

Long Beach, CA

Proprius Health Medical Group, a regenerative medicine clinic in Long Beach, specializes in orthobiologic treatments for musculoskeletal and spine conditions, including platelet-rich plasma therapy a…

  • PRP Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Testosterone Replacement Therapy (TRT)
Polaris Insight Center, Ketamine Assisted Psychotherapy
(1)
Physician reported in record

Polaris Insight Center, Ketamine Assisted Psychotherapy

San Francisco, CA

Polaris Insight Center, a Ketamine Therapy Clinic in San Francisco, offers Ketamine-Assisted Psychotherapy alongside integrative psychiatry and integration therapy. The clinic provides a structured c…

  • Ketamine Therapy
CLEAR Ketamine + Psychiatry
(17)
Physician reported in record

CLEAR Ketamine + Psychiatry

Thousand Oaks, CA

CLEAR Ketamine + Psychiatry, in Westlake Village, specializes in ketamine therapy for treatment-resistant depression, anxiety, and related conditions. The practice offers genetic testing to inform me…

  • Ketamine Therapy
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Regulatory context

A note on California's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • SB 803 (2023, vetoed) and SB 1012 (2024, stalled)
    Proposed regulated therapeutic access to psilocybin, MDMA, mescaline, and DMT; Governor Newsom vetoed SB 58 (2023) citing lack of treatment guidelines.
  • Local decriminalization resolutions
    Oakland (2019), Santa Cruz (2020), Arcata, San Francisco, and Berkeley have passed non-binding resolutions deprioritizing enforcement of natural psychedelics; no legal therapeutic framework.

California enforces federal DEA scheduling. The Medical Board of California investigates prescriber misconduct, including ketamine diversion and inadequate patient monitoring. Several high-profile California ketamine-related deaths (including Matthew Perry's 2023 overdose) have intensified board scrutiny of clinic practices. DEA enforcement targets compounding, diversion, and Ryan Haight Act telehealth compliance.

Ketamine Therapy in , answered.

Most ketamine therapy clinics in California cluster around Los Angeles and the greater Bay Area, with additional options in San Diego and Sacramento. Coverage thins out considerably in the Central Valley, the far north, and many inland counties. If you live outside a major metro, call ahead about evaluation requirements, session length, and recovery arrangements, since you may need to plan a longer trip and a ride home than you would closer to one of these hubs.

Ketamine therapy generally refers to administering ketamine, by IV infusion, intramuscular injection, or as nasal esketamine, at sub-anesthetic doses to treat depression and, less commonly, other conditions. It appears to act on different brain pathways than standard antidepressants, which is why it is sometimes considered when other treatments have not helped. The formulation, dosing schedule, and whether psychotherapy is included vary by provider, so ask what is actually planned for you.

Short-term effects can include dissociation, elevated blood pressure, nausea, and disorientation during and shortly after a session, which is why monitored recovery time and a driver are standard parts of care. Risk is generally managed through screening, dosing, and supervision rather than eliminated. Ask your provider how they monitor vital signs during treatment, who is present, and what their plan is if you have an unexpected reaction.

Candidacy depends on diagnosis, treatment history, and medical factors such as cardiovascular health, substance use history, and certain psychiatric conditions that a prescriber needs to screen for directly. People with uncontrolled high blood pressure, certain heart conditions, or active psychosis are often told to wait or pursue other options. A thorough evaluation, not a general statewide rule, is what actually determines whether ketamine therapy is appropriate for you.

Ketamine itself is a controlled substance, and licensed physicians and physician assistants working under physician supervision may prescribe and oversee its use, with nurses or nurse practitioners often administering it as part of that team. California does not add a ketamine-specific rule on top of these general professional and controlled-substance requirements. Confirm who is supervising your specific treatment rather than assuming any one setting automatically meets this standard.

Physicians and physician assistants can be checked through the Medical Board of California or the Osteopathic Medical Board of California, and nurses or nurse practitioners through the California Board of Registered Nursing. These lookups confirm license status and show public disciplinary history. They will not tell you how experienced someone is with ketamine specifically, so pair that check with direct questions about training and supervision.

Coverage depends heavily on the formulation: IV ketamine for depression is commonly billed as cash pay, while nasal esketamine may be covered when a plan's specific criteria are met. Ask your insurer directly about authorization and network status, and ask any clinic for an itemized quote covering evaluation, medication, monitoring, and follow-up. This page does not publish average costs because arrangements vary too widely across providers to represent fairly.

This page covers supply and rules across the whole state rather than one metro's neighborhoods, while a city page addresses local geography in more detail and the national hub covers the treatment's mechanism and evidence generally. Unlike an open web search, listing order here is not sold, Featured placement is labeled and capped, and Verified reflects credential checks rather than advertising spend.

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