NAD+, senolytics, telomere therapy, and science-backed longevity interventions
At a Glance You cannot absorb NAD+ directly from oral supplements; the molecule is too large to cross the intestinal lining intact and must be synthesized inside cells from precursors. Oral NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide) do raise blood NAD+ levels by 40-90%, as shown in human trials, but the clinical significance of…
GHK-Cu is a naturally occurring copper tripeptide that influences over 4,000 genes involved in tissue repair, collagen production, and inflammation. Here is what the research shows about this peptide for skin, hair, wound healing, and beyond.
NAD+ levels drop with age, driving fatigue, cognitive decline, and slower cellular repair. Here is how the three main precursors (NMN, NR, and niacin) compare, which brands to trust, and how to decide between oral supplements and IV infusions.
Everything you need to know about NAD+ IV therapy — how it works, what it costs, what the evidence actually shows, how it compares to supplements, side effects, and how to choose a provider. Updated 2026.
NMN and NR both raise NAD+ levels, but they enter the biosynthesis pathway differently and have different bodies of clinical evidence. Here is how the two precursors compare on absorption, human trial data, cost, and practical recommendations.
A thorough guide to NAD+ IV therapy for longevity: how NAD+ decline drives aging, sirtuin and mitochondrial mechanisms, IV versus oral NMN/NR bioavailability, clinical evidence, typical protocols (250-1000mg), and cost breakdown.
At a Glance Session duration: 2-4 hours depending on dose and your tolerance (slower drip = fewer side effects). Common doses: 250 mg (introductory), 500 mg (standard), 750 mg+ (high-dose/therapeutic). Typical cost: $250-$1,000+ per session depending on dose and location. Side effects during infusion are common but manageable – nausea, chest tightness, and cramping usually…
At a Glance NR (nicotinamide riboside) has the most published human clinical trial data among NAD+ precursors. NMN (nicotinamide mononucleotide) has strong preclinical evidence and a rapidly growing body of human studies. Oral NAD+ itself has poor bioavailability – your gut breaks most of it down before it reaches your bloodstream. Typical dosing ranges: NMN…