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218 Best Ketamine Therapy Clinics in California

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Read the Ketamine Therapy guide: evidence, costs and questions to ask

California

Ketamine Therapy clinics in California

Searching for a ketamine clinic in California turns up supply concentrated in a few metro regions rather than spread evenly across the state. The Los Angeles area and the greater Bay Area carry most of California's ketamine therapy capacity, with San Diego and Sacramento adding further options. The Central Valley, the far north, and much of the Inland Empire have comparatively little, so someone outside these population centers should expect to travel, sometimes considerably, to reach an established provider.

California has no ketamine-specific licensing statute beyond the general rules already governing controlled substances. A physician or a supervised physician assistant typically orders and oversees treatment, and a registered nurse or nurse practitioner may administer it as part of that medical team. Treatment is usually delivered in a physician's office or a dedicated infusion suite with monitoring equipment, rather than a purely wellness setting, though wellness-branded locations do exist. Scope of practice for nurse practitioners varies with their supervision agreement, so confirm who is actually present during your session.

To verify a provider, check physicians and physician assistants through the Medical Board of California or, for osteopathic physicians, the Osteopathic Medical Board of California. Check nurses and nurse practitioners through the California Board of Registered Nursing. A clean license record shows someone is permitted to practice; it does not establish ketamine-specific experience or predict how you will respond to treatment.

Before booking, ask who evaluates you, who is present and supervising during the infusion, what is being administered and where it is sourced, and how risks are disclosed in writing. Ask what happens if treatment does not help, and request an itemized quote covering evaluation, medication, monitoring, and any included therapy or follow-up.

This listing's order is not for sale. Featured slots are labeled and limited in number, Verified means a clinic has completed credential checks rather than paid for placement, and browsing Regenerated.com costs patients nothing. Appearing in this directory is not an endorsement of any listed clinic.

The national ketamine therapy hub covers the mechanism and the evidence behind IV ketamine and nasal esketamine in more depth. For more on how to read a listing like this one, see How to read a Regenerated city hub and Featured vs Verified vs organic.

218 Clinics, showing page 5 of 15

Healthy Life Recovery
(107)
Physician reported in record

Healthy Life Recovery

San Diego, CA

Healthy Life Recovery, a ketamine-assisted therapy clinic in San Diego, specializes in addiction treatment with an emphasis on evidence-based clinical protocols. The clinic offers Ketamine Therapy al…

  • Transcranial Magnetic Stimulation (TMS)
  • Neurofeedback Therapy
  • Ketamine Therapy
Interventional Anesthesia & Pain Management Clinic
(58)
Physician reported in record

Interventional Anesthesia & Pain Management Clinic

Pasadena, CA

Interventional Anesthesia & Pain Management Clinic, located in Pasadena, specializes in ketamine infusion therapy for treatment-resistant depression, anxiety, and chronic pain conditions. The clinic …

  • PRP Therapy
  • IV Therapy
  • Ketamine Therapy
  • Stem Cell Therapy
Resiliency Mind+Body Medicine & TMS Therapy
(71)
Physician reported in record

Resiliency Mind+Body Medicine & TMS Therapy

Newport Beach, CA

Resiliency Mind+Body Medicine & TMS Therapy, located in Newport Beach, offers an integrative approach to treatment-resistant depression, anxiety, PTSD, and OCD through ketamine therapy and transcrani…

  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Hormone Replacement Therapy (HRT)
  • NAD IV Therapy
Psychiatry And Counseling
Physician reported in record

Psychiatry And Counseling

Los Angeles, CA

Psychiatry and Counseling Los Angeles, in Los Angeles, offers ketamine therapy for treatment-resistant depression, anxiety, and related mood disorders. The clinic provides outpatient ketamine treatme…

  • Ketamine Therapy
Alchemy Community Therapy Center
Physician reported in record

Alchemy Community Therapy Center

Oakland, CA

Alchemy Community Therapy Center, a nonprofit clinic in Oakland, offers Ketamine Therapy within a framework of inclusive mental-health care. The practice operates on a sliding-scale fee model and pro…

  • Ketamine Therapy
IV Vitamin Therapy
(37)
Physician reported in record

IV Vitamin Therapy

Beverly Hills, CA

IV Vitamin Therapy, located in Beverly Hills, provides intravenous nutrient infusions and ketamine protocols for patients seeking supportive care and functional optimization. The clinic offers Myers …

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • IV Hydration
  • Ketamine Therapy
PointKetamine
(1)
Physician reported in record

PointKetamine

Hidden Valley, CA

PointKetamine, a ketamine-therapy clinic in Westlake Village, combines ketamine-assisted psychotherapy with a broader regenerative-medicine platform. The clinic offers Ketamine Therapy alongside stem…

  • Vitamin IV Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
Ventura Center for Advanced Therapeutics (Ketamine Clinic)
(67)
Physician reported in record

Ventura Center for Advanced Therapeutics (Ketamine Clinic)

SANTA ROSA VA, CA

Ventura Center for Advanced Therapeutics, a Ketamine Therapy Clinic in Camarillo, specializes in ketamine infusions and Spravato (esketamine nasal spray) for treatment-resistant depression, anxiety, …

  • IV Therapy
  • IV Hydration
  • Ketamine Therapy
  • Migraine Treatment
  • Psychedelic Therapy
BrainStim Centers
(10)
Physician reported in record

BrainStim Centers

Valencia, CA

BrainStim Centers, a neuromodulation clinic in Valencia, California, specializes in transcranial magnetic stimulation (TMS) for treatment-resistant depression, anxiety, ADHD, and OCD. The clinic offe…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Stem Cell Therapy
BrightMind Therapy
(19)
Physician reported in record

BrightMind Therapy

San Diego, CA

BrightMind Therapy, a ketamine-therapy clinic in San Diego, specializes in ketamine-assisted treatment for treatment-resistant depression, anxiety, and eating disorders in adolescent and pediatric po…

  • Biofeedback Therapy
  • Ketamine Therapy
Thomas Blake Therapy
(6)
Physician status unknown

Thomas Blake Therapy

Pasadena, CA

Thomas Blake Therapy, a ketamine-assisted therapy clinic in Pasadena, specializes in trauma-informed care for PTSD, anxiety, and complex trauma. The practice offers ketamine therapy within a psychoth…

  • Ketamine Therapy
Tiffany Paul Psychotherapy
(12)
Physician status unknown

Tiffany Paul Psychotherapy

Emeryville, CA

Tiffany Paul, LCSW, offers ketamine-assisted psychotherapy and EMDR intensives in Oakland for treatment-resistant anxiety, depression, PTSD, and complex trauma. The practice focuses on highly sensiti…

  • Ketamine Therapy
Clear Mind Treatment
(1)
Physician reported in record

Clear Mind Treatment

Beverly Hills, CA

Clear Mind Treatment, a neuromodulation and mental-health clinic in Beverly Hills, specializes in ketamine therapy and Transcranial Magnetic Stimulation (TMS) for treatment-resistant depression, anxi…

  • Transcranial Magnetic Stimulation (TMS)
  • Neurofeedback Therapy
  • Ketamine Therapy
  • Psychedelic Therapy
A Better Way Psychiatry & TMS
Physician reported in record

A Better Way Psychiatry & TMS

Pasadena, CA

A Better Way Psychiatry & TMS in Pasadena offers ketamine therapy and esketamine (Spravato) for treatment-resistant depression and related mood disorders, alongside Transcranial Magnetic Stimulation …

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
Harbor Ketamine Clinic
(8)
Physician status unknown

Harbor Ketamine Clinic

Newport Beach, CA

Harbor Ketamine Clinic, located in Newport Beach, specializes in intravenous ketamine infusion therapy for patients with treatment-resistant depression, anxiety, and PTSD. The clinic offers a clinica…

  • Ketamine Therapy
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Regulatory context

A note on California's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • SB 803 (2023, vetoed) and SB 1012 (2024, stalled)
    Proposed regulated therapeutic access to psilocybin, MDMA, mescaline, and DMT; Governor Newsom vetoed SB 58 (2023) citing lack of treatment guidelines.
  • Local decriminalization resolutions
    Oakland (2019), Santa Cruz (2020), Arcata, San Francisco, and Berkeley have passed non-binding resolutions deprioritizing enforcement of natural psychedelics; no legal therapeutic framework.

California enforces federal DEA scheduling. The Medical Board of California investigates prescriber misconduct, including ketamine diversion and inadequate patient monitoring. Several high-profile California ketamine-related deaths (including Matthew Perry's 2023 overdose) have intensified board scrutiny of clinic practices. DEA enforcement targets compounding, diversion, and Ryan Haight Act telehealth compliance.

Ketamine Therapy in , answered.

Most ketamine therapy clinics in California cluster around Los Angeles and the greater Bay Area, with additional options in San Diego and Sacramento. Coverage thins out considerably in the Central Valley, the far north, and many inland counties. If you live outside a major metro, call ahead about evaluation requirements, session length, and recovery arrangements, since you may need to plan a longer trip and a ride home than you would closer to one of these hubs.

Ketamine therapy generally refers to administering ketamine, by IV infusion, intramuscular injection, or as nasal esketamine, at sub-anesthetic doses to treat depression and, less commonly, other conditions. It appears to act on different brain pathways than standard antidepressants, which is why it is sometimes considered when other treatments have not helped. The formulation, dosing schedule, and whether psychotherapy is included vary by provider, so ask what is actually planned for you.

Short-term effects can include dissociation, elevated blood pressure, nausea, and disorientation during and shortly after a session, which is why monitored recovery time and a driver are standard parts of care. Risk is generally managed through screening, dosing, and supervision rather than eliminated. Ask your provider how they monitor vital signs during treatment, who is present, and what their plan is if you have an unexpected reaction.

Candidacy depends on diagnosis, treatment history, and medical factors such as cardiovascular health, substance use history, and certain psychiatric conditions that a prescriber needs to screen for directly. People with uncontrolled high blood pressure, certain heart conditions, or active psychosis are often told to wait or pursue other options. A thorough evaluation, not a general statewide rule, is what actually determines whether ketamine therapy is appropriate for you.

Ketamine itself is a controlled substance, and licensed physicians and physician assistants working under physician supervision may prescribe and oversee its use, with nurses or nurse practitioners often administering it as part of that team. California does not add a ketamine-specific rule on top of these general professional and controlled-substance requirements. Confirm who is supervising your specific treatment rather than assuming any one setting automatically meets this standard.

Physicians and physician assistants can be checked through the Medical Board of California or the Osteopathic Medical Board of California, and nurses or nurse practitioners through the California Board of Registered Nursing. These lookups confirm license status and show public disciplinary history. They will not tell you how experienced someone is with ketamine specifically, so pair that check with direct questions about training and supervision.

Coverage depends heavily on the formulation: IV ketamine for depression is commonly billed as cash pay, while nasal esketamine may be covered when a plan's specific criteria are met. Ask your insurer directly about authorization and network status, and ask any clinic for an itemized quote covering evaluation, medication, monitoring, and follow-up. This page does not publish average costs because arrangements vary too widely across providers to represent fairly.

This page covers supply and rules across the whole state rather than one metro's neighborhoods, while a city page addresses local geography in more detail and the national hub covers the treatment's mechanism and evidence generally. Unlike an open web search, listing order here is not sold, Featured placement is labeled and capped, and Verified reflects credential checks rather than advertising spend.

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