Healthy Life Recovery
- Transcranial Magnetic Stimulation (TMS)
- Neurofeedback Therapy
- Ketamine Therapy
California
Searching for a ketamine clinic in California turns up supply concentrated in a few metro regions rather than spread evenly across the state. The Los Angeles area and the greater Bay Area carry most of California's ketamine therapy capacity, with San Diego and Sacramento adding further options. The Central Valley, the far north, and much of the Inland Empire have comparatively little, so someone outside these population centers should expect to travel, sometimes considerably, to reach an established provider.
California has no ketamine-specific licensing statute beyond the general rules already governing controlled substances. A physician or a supervised physician assistant typically orders and oversees treatment, and a registered nurse or nurse practitioner may administer it as part of that medical team. Treatment is usually delivered in a physician's office or a dedicated infusion suite with monitoring equipment, rather than a purely wellness setting, though wellness-branded locations do exist. Scope of practice for nurse practitioners varies with their supervision agreement, so confirm who is actually present during your session.
To verify a provider, check physicians and physician assistants through the Medical Board of California or, for osteopathic physicians, the Osteopathic Medical Board of California. Check nurses and nurse practitioners through the California Board of Registered Nursing. A clean license record shows someone is permitted to practice; it does not establish ketamine-specific experience or predict how you will respond to treatment.
Before booking, ask who evaluates you, who is present and supervising during the infusion, what is being administered and where it is sourced, and how risks are disclosed in writing. Ask what happens if treatment does not help, and request an itemized quote covering evaluation, medication, monitoring, and any included therapy or follow-up.
This listing's order is not for sale. Featured slots are labeled and limited in number, Verified means a clinic has completed credential checks rather than paid for placement, and browsing Regenerated.com costs patients nothing. Appearing in this directory is not an endorsement of any listed clinic.
The national ketamine therapy hub covers the mechanism and the evidence behind IV ketamine and nasal esketamine in more depth. For more on how to read a listing like this one, see How to read a Regenerated city hub and Featured vs Verified vs organic.
Regulatory context
Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.
California enforces federal DEA scheduling. The Medical Board of California investigates prescriber misconduct, including ketamine diversion and inadequate patient monitoring. Several high-profile California ketamine-related deaths (including Matthew Perry's 2023 overdose) have intensified board scrutiny of clinic practices. DEA enforcement targets compounding, diversion, and Ryan Haight Act telehealth compliance.
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