Skip to content
Homepage
Clinic directory

218 Best Ketamine Therapy Clinics in California

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

  • Loading suggestions…
  • Could not load suggestions.
  • No results found.
  • Loading suggestions…
  • Could not load suggestions.
  • No results found.

Read the Ketamine Therapy guide: evidence, costs and questions to ask

California

Ketamine Therapy clinics in California

Searching for a ketamine clinic in California turns up supply concentrated in a few metro regions rather than spread evenly across the state. The Los Angeles area and the greater Bay Area carry most of California's ketamine therapy capacity, with San Diego and Sacramento adding further options. The Central Valley, the far north, and much of the Inland Empire have comparatively little, so someone outside these population centers should expect to travel, sometimes considerably, to reach an established provider.

California has no ketamine-specific licensing statute beyond the general rules already governing controlled substances. A physician or a supervised physician assistant typically orders and oversees treatment, and a registered nurse or nurse practitioner may administer it as part of that medical team. Treatment is usually delivered in a physician's office or a dedicated infusion suite with monitoring equipment, rather than a purely wellness setting, though wellness-branded locations do exist. Scope of practice for nurse practitioners varies with their supervision agreement, so confirm who is actually present during your session.

To verify a provider, check physicians and physician assistants through the Medical Board of California or, for osteopathic physicians, the Osteopathic Medical Board of California. Check nurses and nurse practitioners through the California Board of Registered Nursing. A clean license record shows someone is permitted to practice; it does not establish ketamine-specific experience or predict how you will respond to treatment.

Before booking, ask who evaluates you, who is present and supervising during the infusion, what is being administered and where it is sourced, and how risks are disclosed in writing. Ask what happens if treatment does not help, and request an itemized quote covering evaluation, medication, monitoring, and any included therapy or follow-up.

This listing's order is not for sale. Featured slots are labeled and limited in number, Verified means a clinic has completed credential checks rather than paid for placement, and browsing Regenerated.com costs patients nothing. Appearing in this directory is not an endorsement of any listed clinic.

The national ketamine therapy hub covers the mechanism and the evidence behind IV ketamine and nasal esketamine in more depth. For more on how to read a listing like this one, see How to read a Regenerated city hub and Featured vs Verified vs organic.

218 Clinics, showing page 7 of 15

Life Span
(30)
Physician status unknown

Life Span

Redding, CA

Life Span, a regenerative medicine clinic in Fresno, offers stem-cell therapy and platelet-rich plasma injections for musculoskeletal and joint conditions, alongside hyperbaric oxygen therapy and che…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • IV Therapy
Integral Counseling and Psychotherapy
(1)
Physician status unknown

Integral Counseling and Psychotherapy

San Francisco, CA

Integral Counseling and Psychotherapy, in San Francisco, specializes in ketamine-assisted psychotherapy alongside eye-movement desensitization and reprocessing (EMDR) and psychedelic-assisted therapy…

  • Ketamine Therapy
  • Psychedelic Therapy
HealthQuest Wellness
(10)
Physician reported in record

HealthQuest Wellness

Irvine, CA

HealthQuest Wellness, located in Irvine, offers a comprehensive regenerative-medicine and functional-medicine practice centered on peptide therapy, hormone optimization, and cell-based treatments. Th…

  • Ozone Therapy
  • IV Therapy
  • Ketamine Therapy
  • Arthritis Treatment
  • Peptide Therapy
Sage Health & Wellness
Physician status unknown

Sage Health & Wellness

San Jose, CA

Sage Health & Wellness in San Jose offers regenerative and supportive-medicine therapies alongside aesthetic services, positioning itself as an integrative longevity clinic. Core offerings include IV…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • IV Therapy
  • IV Hydration
Integraltms
(5)
Physician status unknown

Integraltms

Sunnyvale, CA

Integraltms, a neuromodulation clinic in Sunnyvale, specializes in transcranial magnetic stimulation for treatment-resistant depression and other psychiatric conditions. The clinic offers TMS alongsi…

  • IV Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
San Francisco Therapy and Integration
(13)
Physician status unknown

San Francisco Therapy and Integration

San Francisco, CA

San Francisco Therapy and Integration, a mental-health clinic in San Francisco, offers ketamine therapy alongside evidence-based psychotherapy and integration support. The practice focuses on anxiety…

  • Ketamine Therapy
I Vie Infusions
Physician reported in record

I Vie Infusions

Fresno, CA

I Vie Infusions, an IV therapy clinic in Fresno, California, offers a comprehensive range of intravenous nutrient protocols and custom IV cocktails designed for symptom support and physiologic optimi…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • IV Therapy
Journey Inward Psychotherapy
Physician status unknown

Journey Inward Psychotherapy

Oakland, CA

Journey Inward Psychotherapy, an Oakland-based mental-health clinic, specializes in ketamine therapy and psychedelic-integration work for treatment-resistant depression, anxiety, and trauma. The prac…

  • Ketamine Therapy
  • Psychedelic Therapy
VIP Ketamine Clinics
(2)
Physician status unknown

VIP Ketamine Clinics

Modesto, CA

VIP Ketamine Clinics, a Ketamine Therapy Clinic in Modesto, specializes in ketamine infusions for treatment-resistant depression, mood disorders, and chronic pain. The clinic offers ketamine therapy …

  • Ketamine Therapy
Healthwell Physical Therapy Group
Physician status unknown

Healthwell Physical Therapy Group

San Francisco, CA

Healthwell Physical Therapy Group, a regenerative-medicine clinic in San Francisco, offers a comprehensive range of cell-based therapies, orthobiologics, and energy-based treatments. The clinic featu…

  • PRP Therapy
  • Shockwave Therapy
  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
Dr Drip IV Hydration and Wellness Spa
(5)
Physician status unknown

Dr Drip IV Hydration and Wellness Spa

Lemon Grove, CA

Dr Drip IV Hydration and Wellness Spa, located in Lemon Grove, offers IV nutrient therapy and NAD+ infusions alongside peptide protocols and hormone replacement therapy. The clinic specializes in fun…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • IV Therapy
  • IV Hydration
Psychiatrist
(16)
Physician reported in record

Psychiatrist

Los Angeles, CA

Psychiatrist Los Angeles, a ketamine-therapy clinic in Los Angeles, offers Ketamine Therapy for treatment-resistant depression, anxiety, and related mood disorders. The practice positions ketamine as…

  • Ketamine Therapy
Bay Area Mental Health
(9)
Physician status unknown

Bay Area Mental Health

Campbell, CA

Bay Area Mental Health, a mental-health clinic in Campbell, specializes in ketamine therapy for treatment-resistant depression, anxiety, and PTSD, alongside testosterone replacement therapy and hormo…

  • Ketamine Therapy
  • Hormone Replacement Therapy (HRT)
  • Testosterone Replacement Therapy (TRT)
Los Angeles Therapy Network
(4)
Physician status unknown

Los Angeles Therapy Network

Los Angeles, CA

Los Angeles Therapy Network, a mental health clinic in Los Angeles, offers ketamine-assisted psychotherapy alongside psychotherapeutic modalities including EMDR, sensorimotor therapy, and dialectical…

  • Ketamine Therapy
NeuroRelief Ketamine & Infusion Therapy Los Angeles
Physician reported in record

NeuroRelief Ketamine & Infusion Therapy Los Angeles

Los Angeles, CA

NeuroRelief Ketamine & Infusion Therapy, a ketamine-therapy clinic in Sherman Oaks, specializes in ketamine infusions and esketamine (Spravato) for treatment-resistant depression, anxiety, and chroni…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • IV Therapy
  • Ketamine Therapy
results per page

Regulatory context

A note on California's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • SB 803 (2023, vetoed) and SB 1012 (2024, stalled)
    Proposed regulated therapeutic access to psilocybin, MDMA, mescaline, and DMT; Governor Newsom vetoed SB 58 (2023) citing lack of treatment guidelines.
  • Local decriminalization resolutions
    Oakland (2019), Santa Cruz (2020), Arcata, San Francisco, and Berkeley have passed non-binding resolutions deprioritizing enforcement of natural psychedelics; no legal therapeutic framework.

California enforces federal DEA scheduling. The Medical Board of California investigates prescriber misconduct, including ketamine diversion and inadequate patient monitoring. Several high-profile California ketamine-related deaths (including Matthew Perry's 2023 overdose) have intensified board scrutiny of clinic practices. DEA enforcement targets compounding, diversion, and Ryan Haight Act telehealth compliance.

Ketamine Therapy in , answered.

Most ketamine therapy clinics in California cluster around Los Angeles and the greater Bay Area, with additional options in San Diego and Sacramento. Coverage thins out considerably in the Central Valley, the far north, and many inland counties. If you live outside a major metro, call ahead about evaluation requirements, session length, and recovery arrangements, since you may need to plan a longer trip and a ride home than you would closer to one of these hubs.

Ketamine therapy generally refers to administering ketamine, by IV infusion, intramuscular injection, or as nasal esketamine, at sub-anesthetic doses to treat depression and, less commonly, other conditions. It appears to act on different brain pathways than standard antidepressants, which is why it is sometimes considered when other treatments have not helped. The formulation, dosing schedule, and whether psychotherapy is included vary by provider, so ask what is actually planned for you.

Short-term effects can include dissociation, elevated blood pressure, nausea, and disorientation during and shortly after a session, which is why monitored recovery time and a driver are standard parts of care. Risk is generally managed through screening, dosing, and supervision rather than eliminated. Ask your provider how they monitor vital signs during treatment, who is present, and what their plan is if you have an unexpected reaction.

Candidacy depends on diagnosis, treatment history, and medical factors such as cardiovascular health, substance use history, and certain psychiatric conditions that a prescriber needs to screen for directly. People with uncontrolled high blood pressure, certain heart conditions, or active psychosis are often told to wait or pursue other options. A thorough evaluation, not a general statewide rule, is what actually determines whether ketamine therapy is appropriate for you.

Ketamine itself is a controlled substance, and licensed physicians and physician assistants working under physician supervision may prescribe and oversee its use, with nurses or nurse practitioners often administering it as part of that team. California does not add a ketamine-specific rule on top of these general professional and controlled-substance requirements. Confirm who is supervising your specific treatment rather than assuming any one setting automatically meets this standard.

Physicians and physician assistants can be checked through the Medical Board of California or the Osteopathic Medical Board of California, and nurses or nurse practitioners through the California Board of Registered Nursing. These lookups confirm license status and show public disciplinary history. They will not tell you how experienced someone is with ketamine specifically, so pair that check with direct questions about training and supervision.

Coverage depends heavily on the formulation: IV ketamine for depression is commonly billed as cash pay, while nasal esketamine may be covered when a plan's specific criteria are met. Ask your insurer directly about authorization and network status, and ask any clinic for an itemized quote covering evaluation, medication, monitoring, and follow-up. This page does not publish average costs because arrangements vary too widely across providers to represent fairly.

This page covers supply and rules across the whole state rather than one metro's neighborhoods, while a city page addresses local geography in more detail and the national hub covers the treatment's mechanism and evidence generally. Unlike an open web search, listing order here is not sold, Featured placement is labeled and capped, and Verified reflects credential checks rather than advertising spend.

Filters

Rating

Treatments

Advanced Therapies 1
Chronic, Immune & Hormonal
Digestive & Respiratory
IV & Infusion
Pain & Musculoskeletal
Skin & Aesthetics
Mental Health & Neurology