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218 Best Ketamine Therapy Clinics in California

Compare clinic listings by treatment and location. A listing is not a medical endorsement. Organic rank is never for sale; Featured placements are labeled and separate from organic results.

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Read the Ketamine Therapy guide: evidence, costs and questions to ask

California

Ketamine Therapy clinics in California

Searching for a ketamine clinic in California turns up supply concentrated in a few metro regions rather than spread evenly across the state. The Los Angeles area and the greater Bay Area carry most of California's ketamine therapy capacity, with San Diego and Sacramento adding further options. The Central Valley, the far north, and much of the Inland Empire have comparatively little, so someone outside these population centers should expect to travel, sometimes considerably, to reach an established provider.

California has no ketamine-specific licensing statute beyond the general rules already governing controlled substances. A physician or a supervised physician assistant typically orders and oversees treatment, and a registered nurse or nurse practitioner may administer it as part of that medical team. Treatment is usually delivered in a physician's office or a dedicated infusion suite with monitoring equipment, rather than a purely wellness setting, though wellness-branded locations do exist. Scope of practice for nurse practitioners varies with their supervision agreement, so confirm who is actually present during your session.

To verify a provider, check physicians and physician assistants through the Medical Board of California or, for osteopathic physicians, the Osteopathic Medical Board of California. Check nurses and nurse practitioners through the California Board of Registered Nursing. A clean license record shows someone is permitted to practice; it does not establish ketamine-specific experience or predict how you will respond to treatment.

Before booking, ask who evaluates you, who is present and supervising during the infusion, what is being administered and where it is sourced, and how risks are disclosed in writing. Ask what happens if treatment does not help, and request an itemized quote covering evaluation, medication, monitoring, and any included therapy or follow-up.

This listing's order is not for sale. Featured slots are labeled and limited in number, Verified means a clinic has completed credential checks rather than paid for placement, and browsing Regenerated.com costs patients nothing. Appearing in this directory is not an endorsement of any listed clinic.

The national ketamine therapy hub covers the mechanism and the evidence behind IV ketamine and nasal esketamine in more depth. For more on how to read a listing like this one, see How to read a Regenerated city hub and Featured vs Verified vs organic.

218 Clinics, showing page 8 of 15

Ketamine Clinics
Physician reported in record

Ketamine Clinics

Westchester, CA

Ketamine Clinics Los Angeles, in Los Angeles, specializes in ketamine infusion therapy and Spravato (esketamine) for treatment-resistant depression, anxiety, and PTSD, alongside transcranial magnetic…

  • PRP Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Peptide Therapy
  • Testosterone Replacement Therapy (TRT)
Source Healthcare
(151)
Physician status unknown

Source Healthcare

Santa Monica, CA

Source Healthcare, a regenerative-medicine clinic in Santa Monica, specializes in pain management using ketamine infusion therapy and platelet-rich plasma injections alongside conventional interventi…

  • PRP Therapy
  • Ketamine Therapy
  • Arthritis Treatment
Dr. Simone Ravicz, Ph.D.
(2)
Physician status unknown

Dr. Simone Ravicz, Ph.D.

Palm Springs, CA

Simone Ravicz, Ph.D., a licensed psychologist in Palm Springs, offers ketamine-assisted psychotherapy for treatment-resistant depression, anxiety, trauma, and PTSD, alongside hormone replacement ther…

  • Ketamine Therapy
  • Hormone Replacement Therapy (HRT)
The Cure IV
(119)
Physician reported in record

The Cure IV

Beverly Hills, CA

The Cure IV, an IV Therapy Clinic in Beverly Hills, offers customized intravenous nutrient protocols addressing energy, recovery, immune function, and wellness optimization. The clinic provides Myers…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • IV Therapy
  • IV Hydration
  • Ketamine Therapy
Valley Country Market
(6)
Physician status unknown

Valley Country Market

Woodland Hills, CA

Serenity Ketamine Center, located in Woodland Hills, offers ketamine infusion therapy for treatment-resistant depression, chronic pain, and substance-use disorder. The practice brings 23 years of cli…

  • IV Therapy
  • Ketamine Therapy
  • Migraine Treatment
  • Hormone Replacement Therapy (HRT)
Anew Era TMS & Psychiatry
(72)
Physician reported in record

Anew Era TMS & Psychiatry

Torrance, CA

Anew Era TMS & Psychiatry, a ketamine-therapy and psychiatric-care clinic in Torrance, specializes in esketamine (Spravato) and ketamine infusions for treatment-resistant depression and anxiety, alon…

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
KIT Wellness
(1)
Physician reported in record

KIT Wellness

San Diego, CA

KIT Wellness, a ketamine-therapy clinic in San Diego, specializes in ketamine infusion for treatment-resistant depression, anxiety, and PTSD. The clinic offers individualized ketamine protocols admin…

  • Ketamine Therapy
Horizon Pain, Metabolic and stem cell center
(33)
Physician status unknown

Horizon Pain, Metabolic and stem cell center

San Diego, CA

Horizon Pain, Metabolic and Stem Cell Center, a regenerative medicine clinic in San Diego, specializes in stem-cell therapy and platelet-rich plasma injections for chronic pain and musculoskeletal co…

  • PRP Therapy
  • IV Therapy
  • Ketamine Therapy
  • Arthritis Treatment
  • Stem Cell Therapy
True Health
(16)
Physician status unknown

True Health

Glendale, CA

True Health, located in Los Angeles, is an integrative clinic offering ketamine therapy alongside intravenous nutrient protocols including NAD+ and vitamin infusions. The practice also provides plate…

  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • IV Therapy
  • IV Hydration
Southern California TMS Center
Physician reported in record

Southern California TMS Center

West Los Angeles, CA

Southern California TMS Center, in West Los Angeles, specializes in transcranial magnetic stimulation (TMS) and deep TMS therapy for treatment-resistant depression, anxiety, and post-traumatic stress…

  • PRP Therapy
  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Arthritis Treatment
  • Red Light Therapy
San Diego Center for Restorative Medicine
Physician reported in record

San Diego Center for Restorative Medicine

La Jolla, CA

San Diego Center for Restorative Medicine, a regenerative-medicine clinic in La Jolla, specializes in cell-based and energy therapies including stem-cell injections, platelet-rich plasma, exosome the…

  • Stem Cell Therapy
  • NAD IV Therapy
  • Vitamin IV Therapy
  • PRP Therapy
  • Shockwave Therapy
Evolve Healthcare
(71)
Physician reported in record

Evolve Healthcare

Woodland Hills, CA

Evolve Healthcare Woodland Hills, an integrative medicine clinic in Woodland Hills, California, specializes in hormone optimization and peptide therapy for anti-aging and longevity goals. The practic…

  • IV Therapy
  • Ketamine Therapy
  • Peptide Therapy
  • Testosterone Replacement Therapy (TRT)
  • NAD IV Therapy
Kadima Neuropsychiatry Institute
(60)
Physician reported in record

Kadima Neuropsychiatry Institute

La Jolla, CA

Kadima Neuropsychiatry Institute in La Jolla offers ketamine therapy for treatment-resistant depression, anxiety, PTSD, and obsessive-compulsive disorder. The clinic specializes in ketamine-assisted …

  • Transcranial Magnetic Stimulation (TMS)
  • Ketamine Therapy
  • Psychedelic Therapy
LifeSpan medicine
(12)
Physician reported in record

LifeSpan medicine

Santa Monica, CA

LifeSpan Medicine, an integrative longevity clinic in Santa Monica, offers regenerative medicine alongside supportive therapies including IV nutrient infusions, peptide protocols, and hormone optimiz…

  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy
  • Ketamine Therapy
Global Hyperbaric Oxygen Therapy
Physician reported in record

Global Hyperbaric Oxygen Therapy

Los Angeles, CA

Global Hyperbaric Oxygen Therapy Los Angeles, a regenerative-medicine clinic in Los Angeles, offers hyperbaric oxygen therapy (HBOT) alongside a comprehensive range of cellular and supportive therapi…

  • PRP Therapy
  • Ozone Therapy
  • IV Therapy
  • Hyperbaric Oxygen Therapy (HBOT)
  • Oxygen Therapy
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Regulatory context

A note on California's ketamine therapy rules.

Ketamine is a DEA Schedule III controlled substance, FDA-approved as a dissociative anesthetic and used off-label for treatment-resistant depression, PTSD, and chronic pain. The FDA approved esketamine (Spravato) in 2019 for treatment-resistant depression under a Risk Evaluation and Mitigation Strategy (REMS) program that requires in-office administration at certified sites. MDMA-assisted therapy remains Schedule I; the FDA issued a Complete Response Letter in August 2024 to Lykos Therapeutics on its MDMA new drug application. Psilocybin is Schedule I and holds FDA Breakthrough Therapy designation through sponsors such as Compass Pathways and Usona, but has not received FDA approval. Oregon Measure 109 (passed 2020, operational 2023) created a state psilocybin service center framework, and Colorado Proposition 122 (2022) authorized regulated healing centers.

  • SB 803 (2023, vetoed) and SB 1012 (2024, stalled)
    Proposed regulated therapeutic access to psilocybin, MDMA, mescaline, and DMT; Governor Newsom vetoed SB 58 (2023) citing lack of treatment guidelines.
  • Local decriminalization resolutions
    Oakland (2019), Santa Cruz (2020), Arcata, San Francisco, and Berkeley have passed non-binding resolutions deprioritizing enforcement of natural psychedelics; no legal therapeutic framework.

California enforces federal DEA scheduling. The Medical Board of California investigates prescriber misconduct, including ketamine diversion and inadequate patient monitoring. Several high-profile California ketamine-related deaths (including Matthew Perry's 2023 overdose) have intensified board scrutiny of clinic practices. DEA enforcement targets compounding, diversion, and Ryan Haight Act telehealth compliance.

Ketamine Therapy in , answered.

Most ketamine therapy clinics in California cluster around Los Angeles and the greater Bay Area, with additional options in San Diego and Sacramento. Coverage thins out considerably in the Central Valley, the far north, and many inland counties. If you live outside a major metro, call ahead about evaluation requirements, session length, and recovery arrangements, since you may need to plan a longer trip and a ride home than you would closer to one of these hubs.

Ketamine therapy generally refers to administering ketamine, by IV infusion, intramuscular injection, or as nasal esketamine, at sub-anesthetic doses to treat depression and, less commonly, other conditions. It appears to act on different brain pathways than standard antidepressants, which is why it is sometimes considered when other treatments have not helped. The formulation, dosing schedule, and whether psychotherapy is included vary by provider, so ask what is actually planned for you.

Short-term effects can include dissociation, elevated blood pressure, nausea, and disorientation during and shortly after a session, which is why monitored recovery time and a driver are standard parts of care. Risk is generally managed through screening, dosing, and supervision rather than eliminated. Ask your provider how they monitor vital signs during treatment, who is present, and what their plan is if you have an unexpected reaction.

Candidacy depends on diagnosis, treatment history, and medical factors such as cardiovascular health, substance use history, and certain psychiatric conditions that a prescriber needs to screen for directly. People with uncontrolled high blood pressure, certain heart conditions, or active psychosis are often told to wait or pursue other options. A thorough evaluation, not a general statewide rule, is what actually determines whether ketamine therapy is appropriate for you.

Ketamine itself is a controlled substance, and licensed physicians and physician assistants working under physician supervision may prescribe and oversee its use, with nurses or nurse practitioners often administering it as part of that team. California does not add a ketamine-specific rule on top of these general professional and controlled-substance requirements. Confirm who is supervising your specific treatment rather than assuming any one setting automatically meets this standard.

Physicians and physician assistants can be checked through the Medical Board of California or the Osteopathic Medical Board of California, and nurses or nurse practitioners through the California Board of Registered Nursing. These lookups confirm license status and show public disciplinary history. They will not tell you how experienced someone is with ketamine specifically, so pair that check with direct questions about training and supervision.

Coverage depends heavily on the formulation: IV ketamine for depression is commonly billed as cash pay, while nasal esketamine may be covered when a plan's specific criteria are met. Ask your insurer directly about authorization and network status, and ask any clinic for an itemized quote covering evaluation, medication, monitoring, and follow-up. This page does not publish average costs because arrangements vary too widely across providers to represent fairly.

This page covers supply and rules across the whole state rather than one metro's neighborhoods, while a city page addresses local geography in more detail and the national hub covers the treatment's mechanism and evidence generally. Unlike an open web search, listing order here is not sold, Featured placement is labeled and capped, and Verified reflects credential checks rather than advertising spend.

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